Cas no 5989-81-1 (Lactose monohydrate)
Lactose monohydrate is a crystalline disaccharide carbohydrate derived from milk, consisting of one molecule of glucose and one of galactose, with a single water molecule of hydration. It is widely used as an excipient in pharmaceutical formulations due to its excellent compressibility, flowability, and compatibility with active ingredients. Its inert nature and predictable physicochemical properties make it a preferred filler and binder in tablet and capsule manufacturing. Lactose monohydrate also serves as a carrier in dry powder inhalers and a diluent in food applications. Its consistent particle size distribution and high purity ensure reliable performance in industrial and laboratory settings.
Lactose monohydrate structure
Product Name:Lactose monohydrate
CAS No:5989-81-1
MF:C12H24O12
MW:360.3118
MDL:MFCD00150747
CID:85508
PubChem ID:104938
Update Time:2025-10-23
Lactose monohydrate Chemical and Physical Properties
Names and Identifiers
-
- Lactose Monohydrate
- α-Lactose monohydrate
- LACTOSE MONOHYDRATE, a-(RG) PrintBack
- α-Lactose
- alpha-D-Lactose Monohydrate
- α-D(+)-Lactose monohydrate
- β-D-Gal-(1→4)-α-D-Glc
- Lactose,monohydrate, a-(8CI)
- a-D-Glucopyranose, 4-O-b-D-galactopyranosyl-, monohydrate(9CI)
- 4-O-b-D-Galactopyranosyl-a-D-glucopyranose monohydrate
- Aeroflo 20
- Aeroflo 65
- Aeroflo 95
- GranuLac 200
- Granulac 230
- Inhalac 120
- Inhalac 230
- Lactose 100M
- Lactose D 80
- Pharmatose 150M
- Pharmatose 325
- Pharmatose 50M
- Pharmatose 90M
- Pharmatose DCL 11
- Zeparox
- a-D-Lactose monohydrate
- a-Lactose monohydrate
- ludipress
- Lactose
- α-D-Lactose monohydrate
- alpha-Lactose monohydrate
- Lactose, monohydrate
- alpha-lactose hydrate
- Lactose monohydrate [NF]
- D-Lactose monohydrate
- EWQ57Q8I5X
- alpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-, monohydrate
- Lactose monohydrate (NF)
- Lactose Monohydrate (Alpha-Form)
- Pharmaose
- Respitose
- Microtose
- (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5
- ALPHA-D-LACTOSE
- DTXSID1052828
- LACTOSE MONOHYDRATE [EP MONOGRAPH]
- NS00099491
- Lactohale
- LACTOSE,MONOHYDRATE
- (2S,3R,4R,5S,6R)-6-(Hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol hydrate
- -D-Glucopyranose, 4-O-BATE-D-galactopyranosyl-, hydrate(1:1)
- A-D-galactopyranosyl-, hydrate(1:1)
- alpha-Lactose monohydrate, BioXtra, >=99% total lactose basis (GC)
- CS-0128727
- lactose hydrate
- Lactose (TN)
- PHARMATOSE DCL II [II]
- 64044-51-5
- D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate
- Supertab 14sd
- alpha-Lactose, analytical standard
- alpha-4-O-(beta-D-galactopyranosido)-D-glucopyranose
- Wyndale
- SCHEMBL16787
- Pharmatose dcl ii
- Lactose fastflo 316
- A-Lactose (hydrate)
- HY-W087904
- .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate
- Lactochem
- Spherolac 100
- Lactopress spray dried
- alpha -lactose monohydrate
- Lactose hydrous
- Pharmatose DCL 14
- 4-O-A-D-Galactopyranosyl-D-glucose
- 10039-26-6
- Pharmatose
- LACTOSE MONOHYDRATE [USP-RS]
- D03226
- AKOS015896871
- LACTOSUM, MONOHYDRATE [WHO-IP LATIN]
- LACTOSE, HYDROUS [II]
- A-D-Glucopyranose, 4-O-
- NSC 760401
- alpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-, hydrate
- Supertab 50 odt
- alpha-Lactose monohydrate, suitable for cell culture, BioReagent
- Supertab 11sd
- D-Glucose, 4-O-beta-D-galactopyranosyl-, monohydrate
- FS-3862
- 5989-81-1
- (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate
- alpha-Lactose monohydrate, >=99% total lactose basis (GC)
- CHEBI:189432
- NSC-760401
- a-D-Glucopyranose, 4-O-b-D-galactopyranosyl-, monohydrate
- Lactose (JP17)
- LACTOSE HYDRATE [JAN]
- Inhalac 120 (contains b anomer)
- alpha-Lactose (hydrate)
- EN300-1608278
- 66857-12-3
- Wynhale
- .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1)
- E80712
- LACTOSE MONOHYDRATE [II]
- UNII-EWQ57Q8I5X
- Lactopress
- 4-O-beta-D-Galactopyranosyl-alpha-D-glucose
- /b-D-galactopyranosyl-(1,4)-D-glucose monhydrate
- Lactose(Monohydrate)
- Q27277391
- Supertab 11sd nz
- (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol hydrate
- Supertab 30gr
- Lactose, hydrous
- LACTOSE MONOHYDRATE [WHO-IP]
- Lactose monohydrate
-
- MDL： MFCD00150747
- Inchi： 1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
- InChI Key： WSVLPVUVIUVCRA-KPKNDVKVSA-N
- SMILES： O([C@@]1([H])[C@@]([H])([C@]([H])([C@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])O[H])O[H])[C@]1([H])[C@@]([H])(C([H])([H])O[H])O[C@@]([H])([C@@]([H])([C@@]1([H])O[H])O[H])O[H].O([H])[H]
Computed Properties
- Exact Mass: 360.12700
- Monoisotopic Mass: 360.127
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 9
- Hydrogen Bond Acceptor Count: 12
- Heavy Atom Count: 24
- Rotatable Bond Count: 4
- Complexity: 382
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 10
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- XLogP3: -4.7
- Topological Polar Surface Area: 191
Experimental Properties
- Color/Form: White crystals.
- Density: 1,53 g/cm3
- Melting Point: 211.8 oC
- Boiling Point: 412.35°C (rough estimate)
- Flash Point: 357.8 °C
- Refractive Index: 1.6480 (estimate)
- Solubility: H2O: soluble1M, clear, colorless
- Water Partition Coefficient: Soluble in water.
- PSA: 198.76000
- LogP: -5.46150
- Solubility: Soluble in water, slightly soluble in glacial acetic acid, insoluble in alcohol and ether.
Lactose monohydrate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： R34: can cause burns.
- Safety Instruction： S24/25; S36; S26
- RTECS：OD9625000
-
Hazardous Material Identification：
- TSCA：Yes
- Storage Condition：room temp
- Safety Term：S24/25
- Risk Phrases：R40
Lactose monohydrate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 47287-U |
Lactose monohydrate |
5989-81-1 | analytical standard | 1KIT |
242.46 | 2021-05-13 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-GN056-500g |
Lactose monohydrate |
5989-81-1 | 98% | 500g |
￥102.0 | 2022-03-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-GN056-100g |
Lactose monohydrate |
5989-81-1 | 98% | 100g |
￥50.0 | 2022-03-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-CS360-50mg |
Lactose monohydrate |
5989-81-1 | 50mg |
￥91.0 | 2022-07-28 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-MK032-100g |
Lactose monohydrate |
5989-81-1 | ，≥99.5% (HPLC) | 100g |
￥113.0 | 2022-07-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-NJ567-100g |
Lactose monohydrate |
5989-81-1 | USP | 100g |
￥50.0 | 2022-03-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-MK032-25g |
Lactose monohydrate |
5989-81-1 | ，≥99.5% (HPLC) | 25g |
￥50.0 | 2022-07-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-JX549-100g |
Lactose monohydrate |
5989-81-1 | ,≥98% | 100g |
￥63.0 | 2022-07-28 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | L2643-500G |
Lactose monohydrate |
5989-81-1 | 500g |
￥289.07 | 2023-09-23 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | L2643-5KG |
Lactose monohydrate |
5989-81-1 | 5kg |
￥1733.18 | 2023-09-23 |
Lactose monohydrate Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:5989-81-1)Alpha-D-Lactose monohydrate
Order Number:sfd448
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
Price ($):discuss personally
Email:[email protected]
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:5989-81-1)Lactose monohydrate
Order Number:A1203173
Stock Status:in Stock
Quantity:25kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 02:49
Price ($):280.0
Email:[email protected]
Lactose monohydrate Related Literature
-
Sergey Mitryukovskiy,Danny E. P. Vanpoucke,Yue Bai,Théo Hannotte,Mélanie Lavancier,Djamila Hourlier,Goedele Roos,Romain Peretti Phys. Chem. Chem. Phys. 2022 24 6107
-
K. Vinodhini,K. Srinivasan CrystEngComm 2015 17 6376
-
P. Parimaladevi,K. Srinivasan CrystEngComm 2016 18 2312
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4. Radiation chemistry of carbohydrates. Part XVIII. The extreme and variable susceptibility of crystalline lactose to ionising radiationsN. U. Ahmed,P. J. Baugh,G. O. Phillips J. Chem. Soc. Perkin Trans. 2 1972 1305
-
Vishal Raval,Humera Siddique,Cameron J. Brown,Alastair J. Florence CrystEngComm 2020 22 2288
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