• 1. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 2. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 3. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 4. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 5. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzopyrazoles Indazoles

Comprehensive Overview of 5,6-Dinitroindazole (CAS No. 59601-91-1): Properties, Applications, and Research Insights

5,6-Dinitroindazole (CAS No. 59601-91-1) is a specialized nitro-substituted indazole derivative that has garnered significant attention in organic chemistry and materials science. With its unique molecular structure featuring two nitro groups at the 5- and 6-positions of the indazole ring, this compound exhibits distinct chemical reactivity and potential applications. Researchers and industry professionals often search for terms like "5,6-Dinitroindazole synthesis", "CAS 59601-91-1 applications", or "nitroindazole derivatives", reflecting growing interest in its properties and uses.

The compound's molecular formula, C₇H₄N₄O₄, and molecular weight of 208.13 g/mol make it a subject of study in heterocyclic chemistry. Recent trends show increased searches for "green chemistry approaches for nitroindazoles" and "5,6-Dinitroindazole solubility data", indicating demand for environmentally friendly synthesis methods and physicochemical characterization. The compound's crystalline nature and moderate stability under standard conditions contribute to its research utility.

In pharmaceutical research, 5,6-Dinitroindazole serves as a valuable intermediate for developing novel bioactive compounds. While not itself therapeutic, its structural features make it a key building block in medicinal chemistry explorations. Search analytics reveal frequent queries about "indazole derivatives in drug discovery" and "nitro group reactivity in heterocycles", highlighting its relevance to modern drug development strategies. The compound's electron-deficient aromatic system enables diverse substitution reactions valuable for structure-activity relationship studies.

Materials science applications of CAS 59601-91-1 include its potential use in advanced functional materials. Researchers investigating "nitroaromatic compounds for electronic materials" or "indazole-based coordination complexes" often encounter this compound. Its ability to participate in charge-transfer interactions and coordinate with metal ions makes it interesting for designing novel materials with tailored electronic properties. Recent publications have explored its derivatives in contexts ranging from organic semiconductors to metal-organic frameworks.

Analytical characterization of 5,6-Dinitroindazole typically involves techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography. Laboratory professionals frequently search for "59601-91-1 spectroscopic data" and "Dinitroindazole HPLC methods", underscoring the need for reliable analytical protocols. The compound shows characteristic UV-Vis absorption maxima around 260-280 nm and 350-370 nm, valuable for detection and quantification in complex matrices.

Safety considerations for handling 5,6-Dinitroindazole follow standard laboratory practices for nitroaromatic compounds. While not classified as highly hazardous, proper personal protective equipment and ventilation are recommended during manipulation. The scientific community shows growing interest in "sustainable handling of nitro compounds" and "biodegradation of nitrated heterocycles", reflecting broader environmental consciousness in chemical research.

Future research directions for CAS 59601-91-1 may explore its catalytic applications or further modifications to enhance specific properties. Emerging search terms like "catalytic applications of nitroindazoles" and "59601-91-1 derivative libraries" suggest expanding investigation areas. The compound's versatility continues to make it a valuable tool for synthetic chemists developing new methodologies in heterocyclic chemistry.

Commercial availability of 5,6-Dinitroindazole varies by region, with specialty chemical suppliers typically offering it for research purposes. Procurement-related searches often include "59601-91-1 suppliers" and "Dinitroindazole pricing", indicating practical considerations for researchers. Proper storage in cool, dry conditions away from strong oxidizers helps maintain its stability over extended periods.

In summary, 5,6-Dinitroindazole (CAS No. 59601-91-1) represents an important nitro-substituted heterocycle with diverse research applications. Its unique chemical properties and synthetic versatility continue to inspire investigations across multiple disciplines, from fundamental organic chemistry to applied materials science. The compound's ongoing relevance is evidenced by persistent search interest and frequent appearance in recent scientific literature.

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