• 1. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
• 2. An Assessment of the Laminar Hypersonic Double-Cone Experiments in the LENS-XX Tunnel
  JaideepRay,PatrickBlonigan,EricT.Phipps,KathrynMaupin
• 3. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
  M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
• 4. An atmosphere and light tuned highly diastereoselective synthesis of cyclobuta/penta[b]indoles from aniline-tethered alkylidenecyclopropanes with alkynes?
  Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
• 5. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699

Introduction to [1,1'-Biphenyl]-4-ol,3,4'-dibromo (CAS No. 59452-49-2)

[1,1'-Biphenyl]-4-ol,3,4'-dibromo is a specialized organic compound that has garnered significant attention in the field of pharmaceutical and chemical research due to its unique structural properties and potential applications. This compound, identified by its CAS number 59452-49-2, belongs to the biphenyl family, which is known for its diverse chemical reactivity and utility in various industrial and scientific applications.

The molecular structure of [1,1'-Biphenyl]-4-ol,3,4'-dibromo consists of two benzene rings connected by a central bridge, with bromine atoms attached at the 3 and 4' positions and a hydroxyl group at the 4 position. This specific arrangement imparts distinct electronic and steric properties to the molecule, making it a valuable candidate for further study and development.

In recent years, there has been a growing interest in biphenyl derivatives due to their role as intermediates in the synthesis of more complex molecules. The presence of bromine atoms in [1,1'-Biphenyl]-4-ol,3,4'-dibromo enhances its reactivity, allowing for various functionalization strategies that can be exploited in drug design and material science.

One of the most compelling aspects of [1,1'-Biphenyl]-4-ol,3,4'-dibromo is its potential application in pharmaceutical research. The biphenyl core is a common motif in many bioactive compounds, and modifications to this core can lead to novel therapeutic agents. The hydroxyl group and bromine substituents provide multiple sites for chemical modification, enabling researchers to tailor the properties of the molecule for specific biological targets.

Recent studies have explored the use of biphenyl derivatives as building blocks for antifungal and anti-inflammatory agents. The structural features of [1,1'-Biphenyl]-4-ol,3,4'-dibromo make it a promising candidate for these applications. Researchers have demonstrated that the bromine atoms can participate in various chemical reactions, such as cross-coupling reactions, which are widely used in the synthesis of complex organic molecules.

The hydroxyl group at the 4 position also plays a crucial role in the reactivity of [1,1'-Biphenyl]-4-ol,3,4'-dibromo. This functional group can engage in hydrogen bonding interactions with biological targets, enhancing the binding affinity of the molecule. Additionally, it can be used as a site for further derivatization, allowing for the creation of more sophisticated pharmacophores.

In material science, biphenyl derivatives like [1,1'-Biphenyl]-4-ol,3,4'-dibromo have been investigated for their potential use in organic electronics. The rigid structure of biphenyl-based compounds makes them suitable candidates for use as semiconductors and light-emitting diodes (LEDs). The bromine substituents can be used to fine-tune the electronic properties of these materials, leading to improved performance in electronic devices.

The synthesis of [1,1'-Biphenyl]-4-ol，3，4' - dibromo involves multi-step organic reactions that require careful control of reaction conditions. The introduction of bromine atoms into the biphenyl core typically involves halogenation reactions， which can be performed using various halogenating agents. The hydroxyl group is often introduced through hydroxylation or oxidation reactions， depending on the synthetic route chosen.

One of the key challenges in synthesizing this compound is maintaining regioselectivity during bromination. The presence of multiple reactive sites on the biphenyl ring means that unwanted side reactions can occur if conditions are not carefully controlled. Advanced techniques such as transition metal catalysis have been employed to improve selectivity and yield.

Once synthesized， [1，1' - Biphenyl] - 4 - ol，3，4' - dibromo can be further functionalized to create more complex molecules. For example， it can undergo cross-coupling reactions with other organic substrates to introduce additional functional groups or alter the connectivity between rings. These modifications can significantly impact the biological activity and material properties of the resulting compounds.

The growing body of research on biphenyl derivatives underscores their importance as versatile building blocks in pharmaceutical and materials science. [1，1' - Biphenyl] - 4 - ol，3，4' - dibromo represents just one example of how these compounds can be harnessed for innovative applications. As research continues to uncover new uses for biphenyl-based molecules， their significance is likely to grow even further.

• 87682-04-0([1,1'-Biphenyl]-2,2'-diol, 3,3'-dibromo-5,5'-dimethyl-)
• 189039-64-3(3,3'-Dibromo-4,4'-biphenol)
• 92-03-5(3-bromo-1,1'-biphenyl-4-ol)
• 29558-77-8(4-Bromo-4'-hydroxybiphenyl)
• 4544-71-2(2,6-dibromo-4-(4-bromophenyl)phenol)
• 1261929-64-9(3-Bromo-5-(3-methylphenyl)phenol)
• 1261952-04-8(3-Bromo-5-(3-hydroxyphenyl)phenol)
• 6627-55-0(2-Bromo-4-methylphenol)
• 149950-41-4(4'-BROMO-BIPHENYL-3-OL)
• 1261925-01-2(3-Bromo-5-(3,5-dimethylphenyl)phenol)