Cas no 58812-37-6 (Toosendanin)
Toosendanin is a bioactive triterpenoid compound primarily extracted from the bark or seeds of Melia toosendan, a plant belonging to the Meliaceae family. It exhibits notable insecticidal, anthelmintic, and neurotoxic properties, making it a subject of interest in agricultural and pharmacological research. Toosendanin acts as a selective blocker of neurotransmitter release, particularly at neuromuscular junctions, which contributes to its efficacy against certain pests and parasites. Its mechanism involves disrupting calcium ion channels, leading to paralysis in target organisms. The compound is also studied for potential anti-tumor and anti-inflammatory applications. Its natural origin and specific activity profile offer advantages in integrated pest management and biomedical research.
Toosendanin structure
Product Name:Toosendanin
CAS No:58812-37-6
MF:C30H38O11
MW:574.61613035202
MDL:MFCD00210564
CID:57331
PubChem ID:9851101
Update Time:2025-12-17
Toosendanin Chemical and Physical Properties
Names and Identifiers
-
- Toosendanin
- 24-Norchola-20,22-diene-4-carboxaldehyde,3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-,cyclic4,19-hemiacetal, [C(R),1α,3α,4β, 5α,7α,12α,13α,14β,15β,17α]-
- Chuanliansu
- 28-Deacetylsendanin
- 12-AcetoxyaMoorastatin
- Trichilinin
- N1864
- [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16S,19R,21S)-4-Acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-
- Q-100679
- MFCD00210564
- CHEBI:192461
- 58812-37-6
- AS-56295
- [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16R,19S,21R)-4-Acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate
- CHEMBL503044
- HY-N0263
- AKOS025311566
- CS-0008285
- [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16R,19S,21R)-4-acetyloxy-6-(uran-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate
- [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15S,16R,19S,21R)-4-Acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate
- SCHEMBL15942911
- NS00067872
- FT-0689315
- B0005-464304
- [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16R,19S,21R)-4-acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.0^{1,14.0^{2,11.0^{5,10.0^{8,10]henicosan-21-yl] acetate
- [4-Acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate
-
- MDL： MFCD00210564
- Inchi： 1S/C30H38O11/c1-13(31)39-20-10-19(34)29-12-38-25(36)26(20,3)17(29)9-18(33)28(5)23(29)22(35)24(40-14(2)32)27(4)16(15-6-7-37-11-15)8-21-30(27,28)41-21/h6-7,11,16-21,23-25,33-34,36H,8-10,12H2,1-5H3/t16-,17-,18+,19-,20+,21+,23-,24-,25+,26+,27+,28+,29+,30+/m0/s1
- InChI Key： NAHTXVIXCMUDLF-RFNFAWMESA-N
- SMILES： O1[C@@H]2C[C@@H](C3=COC=C3)[C@]3(C)[C@H](C([C@@H]4[C@@]56CO[C@H]([C@@](C)([C@@H](C[C@@H]5O)OC(C)=O)[C@@H]6C[C@H]([C@@]4(C)[C@]132)O)O)=O)OC(C)=O
Computed Properties
- Exact Mass: 574.24100
- Monoisotopic Mass: 574.24141202 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 11
- Heavy Atom Count: 41
- Rotatable Bond Count: 5
- Complexity: 1190
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 12
- Undefined Atom Stereocenter Count : 2
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 574.6
- XLogP3: 0.7
- Topological Polar Surface Area: 165
Experimental Properties
- Color/Form: Powder
- Density: 1.2084 (rough estimate)
- Melting Point: 244-245°C
- Boiling Point: 714℃ at 760 mmHg
- Refractive Index: 1.5970 (estimate)
- PSA: 165.26000
- LogP: 1.46610
Toosendanin Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： 24/25
- Storage Condition：Store at 4°C,-4At ℃Store…Better
Toosendanin Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-N0263-10mM*1mLinDMSO |
Toosendanin |
58812-37-6 | ≥98.0% | 10mM*1mLinDMSO |
￥632 | 2023-07-25 | |
| MedChemExpress | HY-N0263-5mg |
Toosendanin |
58812-37-6 | 98.77% | 5mg |
￥500 | 2025-04-16 | |
| MedChemExpress | HY-N0263-10mg |
Toosendanin |
58812-37-6 | 98.77% | 10mg |
￥650 | 2025-04-16 | |
| MedChemExpress | HY-N0263-20mg |
Toosendanin |
58812-37-6 | ≥98.0% | 20mg |
￥1800 | 2022-10-09 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T102728-50mg |
Toosendanin |
58812-37-6 | ,≥98% | 50mg |
￥3024.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T102728-10mg |
Toosendanin |
58812-37-6 | ,≥98% | 10mg |
￥795.90 | 2023-09-01 | |
| ChemFaces | CFN99908-20mg |
Toosendanin |
58812-37-6 | >=98% | 20mg |
$100 | 2021-07-22 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BZP0187-20mg |
Toosendanin |
58812-37-6 | HPLC≥98% | 20mg |
￥600元 | 2023-09-15 | |
| DC Chemicals | DCC-016-20 mg |
Toosendanin |
58812-37-6 | >98%, Standard References Grade | 20mg |
$280.0 | 2022-02-28 | |
| ChemFaces | CFN99908-20mg |
Toosendanin |
58812-37-6 | >=98% | 20mg |
$100 | 2023-09-19 |
Toosendanin Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:58812-37-6)Toosendanin
Order Number:LE10382;LE26658179
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:03
Price ($):discuss personally
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:58812-37-6)Toosendanin
Order Number:sfd472
Stock Status:in Stock
Quantity:200kg
Purity:99%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
Price ($):discuss personally
Email:[email protected]
Toosendanin Related Literature
-
Yong Guo,Xiaoguang Wang,Lailiang Qu,Shengnan Xu,Yi Zhao,Ruoqian Xie,Mengxing Huang,Yanbing Zhang RSC Adv. 2017 7 11796
-
Yong Guo,Lailiang Qu,Xiaoguang Wang,Mengxing Huang,Lu Jia,Yanbing Zhang RSC Adv. 2016 6 93505
-
Jiu-Lin Huang,Min Lv,Hui Xu RSC Adv. 2017 7 15997
-
Xiang Yu,Danfeng Shi,Xiaoyan Zhi,Qin Li,Xiaojun Yao,Hui Xu RSC Adv. 2015 5 31700
-
Xiang Yu,Gang Feng,Jiulin Huang,Hui Xu RSC Adv. 2016 6 30405
Related Categories
- Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Limonoids
- Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Triterpenoids Limonoids
- Triterpenoids
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
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