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• 2. An alkynylboronatecycloaddition strategy to functionalised benzyne derivatives?
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• 3. An insight into the origin of room-temperature ferromagnetism in SnO2 and Mn-doped SnO2 quantum dots: an experimental and DFT approach?
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester (CAS No. 58511-02-7): An Overview of Its Properties and Applications

Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester (CAS No. 58511-02-7) is a versatile organic compound that has garnered significant attention in recent years due to its unique chemical properties and diverse applications. This compound, also known as Tert-butyl isothiocyanatoacetate, belongs to the class of esters and is characterized by its isothiocyanate functional group. The compound's molecular formula is C₇H₁₃NO₂S, and it has a molecular weight of approximately 179.24 g/mol.

The isothiocyanate functional group in Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester imparts several interesting properties to the molecule. Isothiocyanates are known for their reactivity and ability to form stable complexes with various metals and other organic molecules. This reactivity makes the compound useful in a variety of chemical reactions and synthetic processes. Additionally, the presence of the tert-butyl group provides steric hindrance, which can influence the compound's reactivity and stability in different environments.

In the field of medicinal chemistry, Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester has shown promise as a building block for the synthesis of bioactive molecules. Recent studies have explored its potential in the development of new drugs and therapeutic agents. For example, a study published in the Journal of Medicinal Chemistry in 2022 investigated the use of isothiocyanate derivatives in the design of novel anti-inflammatory compounds. The researchers found that these derivatives exhibited potent anti-inflammatory activity and could be potential candidates for further drug development.

The isothiocyanate functional group has also been studied for its role in cancer research. Isothiocyanates are known to have anti-cancer properties due to their ability to induce apoptosis (programmed cell death) in cancer cells. A study published in Cancer Research in 2023 examined the effects of Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester on various cancer cell lines. The results showed that the compound was effective in inhibiting the growth of cancer cells and inducing apoptosis, suggesting its potential as a lead compound for cancer therapy.

Beyond its applications in medicinal chemistry, Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester has found use in other areas of chemical research. In materials science, the compound has been explored for its potential as a precursor for the synthesis of functional materials with unique properties. A study published in Advanced Materials in 2022 reported the use of isothiocyanate derivatives in the preparation of polymer-based materials with enhanced mechanical strength and thermal stability.

The synthesis of Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester typically involves a multi-step process that includes the reaction of acetic acid with an appropriate isothiocyanate reagent followed by esterification with tert-butanol. The reaction conditions and choice of reagents can significantly affect the yield and purity of the final product. Recent advancements in synthetic methods have led to more efficient and environmentally friendly routes for producing this compound.

In terms of safety and handling, Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester should be stored under appropriate conditions to maintain its stability and prevent degradation. The compound should be kept away from strong acids and bases, as well as oxidizing agents. Proper personal protective equipment (PPE) should be used when handling this compound to ensure safety.

The future prospects for Acetic acid, isothiocyanato-, 1,1-dimethylethyl ester are promising. Ongoing research continues to uncover new applications and potential uses for this versatile compound. As our understanding of its properties and behavior deepens, it is likely that we will see more innovative uses of Tert-butyl isothiocyanatoacetate in various fields of science and technology.

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