Cas no 58480-54-9 (Lehmannine)

Lehmannine structure
Lehmannine structure
Product Name:Lehmannine
CAS No:58480-54-9
MF:C15H22N2O
MW:246.347983837128
CID:1610505
PubChem ID:3041752
Update Time:2025-07-16

Lehmannine Chemical and Physical Properties

Names and Identifiers

    • 12,13-didehydromatridin-15-one
    • 1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,11,13a,13b,13c-decahydro-, (7aS,13aR,13bS,13cS)-
    • Lemannine
    • Lehmannine
    • Lehmanine
    • Matridin-15-one,12,13-didehydro
    • (7aS,13aR,13bS,13cS)-2,3,6,7,7a,8,11,13a,13b,13c-Decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
    • (41S,7AS,13aR,13bS)-2,3,41,6,7,7a,8,11,13a,13b-decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
    • BRN 0885357
    • (+)-lehmannine
    • DTXSID60207179
    • AKOS040761978
    • (1S,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadec-3-en-6-one
    • CS-0139938
    • 58480-54-9
    • 12-Dehydromatrine
    • HY-N8091
    • starbld0008190
    • MS-23498
    • Matridin-15-one, 12,13-didehydro-
    • CHEMBL205311
    • (1S,2R,9S,17S)-7,13-DIAZATETRACYCLO[7.7.1.0(2),?.0(1)(3),(1)?]HEPTADEC-3-EN-6-ONE
    • 12,13-Didehydro-matridin-15-one; (+)-Lehmannine; (+)-Lemannine; 12-Dehydromatrine; 2,3,6,7,7a,8,11,13a,13b,13c-Decahydro-[7aS-(7aa,13ass,13ba,13ca)]-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one; Lemannine
    • G13040
    • DA-64911
    • Inchi: 1S/C15H22N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h1,6,11-13,15H,2-5,7-10H2/t11-,12+,13+,15-/m0/s1
    • InChI Key: WUVYENIUARJBNM-JLNYLFASSA-N
    • SMILES: O=C1CC=C[C@@H]2[C@H]3CCCN4CCC[C@@H](CN21)[C@H]43

Computed Properties

  • Exact Mass: 246.17300
  • Monoisotopic Mass: 246.173213330g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 0
  • Complexity: 392
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.5
  • Topological Polar Surface Area: 23.6?2

Experimental Properties

  • Color/Form: Cryst.
  • PSA: 23.55000
  • LogP: 1.52350

Lehmannine Pricemore >>

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Additional information on Lehmannine

Comprehensive Overview of Lehmannine (CAS No. 58480-54-9): Properties, Applications, and Research Insights

Lehmannine (CAS No. 58480-54-9) is a naturally occurring alkaloid compound that has garnered significant attention in recent years due to its potential applications in pharmacology and biochemistry. This compound, often referred to by its chemical name Lehmannine, belongs to a class of bioactive molecules known for their diverse biological activities. Researchers and industry professionals are increasingly interested in Lehmannine uses and Lehmannine benefits, particularly in the context of drug discovery and natural product development.

The molecular structure of Lehmannine features a unique alkaloid backbone, which contributes to its interaction with biological systems. Studies have explored its potential as a Lehmannine bioactive compound, with preliminary findings suggesting possible applications in modulating cellular pathways. The compound's CAS No. 58480-54-9 serves as a crucial identifier in chemical databases and research literature, ensuring accurate referencing across scientific publications.

Recent trends in natural product research have placed Lehmannine extraction methods and Lehmannine synthesis among the top searched topics in this field. Scientists are particularly interested in optimizing extraction protocols from natural sources, as well as developing efficient synthetic routes for large-scale production. The growing demand for sustainable bioactive compounds aligns perfectly with research into Lehmannine natural sources, making it a relevant subject in green chemistry initiatives.

From a pharmacological perspective, investigations into Lehmannine mechanism of action have revealed interesting interactions with various biological targets. While detailed clinical studies are still ongoing, the compound's Lehmannine biological activity profile shows promise for potential therapeutic applications. Researchers are particularly focused on understanding its structure-activity relationship, which could lead to the development of more potent analogs.

The analytical characterization of Lehmannine involves advanced techniques such as HPLC, mass spectrometry, and NMR spectroscopy. These methods are essential for quality control in Lehmannine production and for verifying the compound's purity in research settings. The CAS No. 58480-54-9 serves as a critical reference point in these analytical procedures, ensuring consistency across different research groups and commercial suppliers.

In the context of current scientific trends, Lehmannine research updates frequently appear in discussions about novel bioactive compounds from natural sources. The compound's potential as a lead molecule in drug discovery has sparked interest among pharmaceutical researchers, particularly in the era of increasing antibiotic resistance and the search for new therapeutic agents. This aligns with broader searches for alternative medicine compounds and plant-derived bioactive molecules.

From a commercial standpoint, the market for specialized alkaloids like Lehmannine has been growing steadily. Suppliers and manufacturers often list Lehmannine CAS 58480-54-9 in their catalogs, catering to research institutions and pharmaceutical developers. The compound's stability profile and solubility characteristics are frequently queried by potential users, highlighting the practical considerations in its application.

Future directions in Lehmannine studies may focus on its potential synergistic effects with other compounds, an area of growing interest in phytochemical research. The scientific community is also keen to explore Lehmannine derivatives that might offer improved bioavailability or target specificity. These developments align with current trends in precision medicine and personalized therapeutics, making Lehmannine a compound worth watching in coming years.

For researchers entering this field, understanding the physicochemical properties of Lehmannine (CAS No. 58480-54-9) is essential. Key parameters such as melting point, optical rotation, and spectral characteristics form the foundation for further investigations. These properties are particularly important when comparing natural Lehmannine with synthetic Lehmannine variants or when developing analytical methods for its detection in complex matrices.

The ecological aspects of Lehmannine-containing plants have also attracted attention, as scientists study the ecological roles of such alkaloids in their native environments. This connects to broader searches about plant defense mechanisms and ecological biochemistry, demonstrating how Lehmannine research intersects with multiple scientific disciplines. The compound's presence in specific plant species and its variation under different growth conditions remain active areas of investigation.

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