Cas no 58470-85-2 (2,6-Diamino-4-hydroxypyrimidine Sulfate)
2,6-Diamino-4-hydroxypyrimidine Sulfate Chemical and Physical Properties
Names and Identifiers
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- 2,6-Diamino-4-hydroxypyrimidine Sulfate
- 2,4-DIAMINO-6-HYDROXYPYRIMIDINE SULFATE
- 2,4-Diaminohypoxanthine
- 2,6-Diamino-4(1H)-pyrimidinone sulfate
- 58470-85-2
- NSC-618283
- SCHEMBL11468643
- EINECS 275-509-6
- AKOS032947378
- 2,4-diamino-1H-pyrimidin-6-one;sulfuric acid
- 2,6-diaminopyrimidin-4-ol sulfate
- 71477-19-5
- 4(1h)-pyrimidinone, 2,6-diamino-, sulfate(1:1)
- 2,6-Diaminopyrimidin-4(3H)-one sulfate(1:x)
- 4-Oxo-1H-pyrimidin-2,6-diamino-4(1H)-pyrimidinone
- 2,6-Diaminopyrimidin-4(3H)-one sulfate
- 2,6-Diaminopyrimidin-4(3H)-onesulfate(1:x)
- 2,6-Diamino-4(1H)-pyrimidinone sulfate (1:1)
- FT-0666373
- NSC618283
- 2,6-Diamino-1H-pyrimidin-4-one;sulfuric acid
- DTXSID0069254
-
- MDL: MFCD00127860
- Inchi: 1S/C4H6N4O.H2O4S/c5-2-1-3(9)8-4(6)7-2;1-5(2,3)4/h1H,(H5,5,6,7,8,9);(H2,1,2,3,4)
- InChI Key: SLSWVEQLCOSOTJ-UHFFFAOYSA-N
- SMILES: S(=O)(=O)(O)O.O=C1C=C(N)N=C(N)N1
Computed Properties
- Exact Mass: 224.02200
- Monoisotopic Mass: 224.022
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 5
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 14
- Rotatable Bond Count: 0
- Complexity: 286
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 177A^2
Experimental Properties
- Color/Form: Yellow solid
- Density: 1.84g/cm3
- Melting Point: 305-312°C
- Boiling Point: 288.5oC at 760 mmHg
- Flash Point: 128.3oC
- Solubility: Hot Water
- PSA: 181.03000
- LogP: 0.93700
- Vapor Pressure: 0.0±1.4 mmHg at 25°C
2,6-Diamino-4-hydroxypyrimidine Sulfate Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement:
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
2,6-Diamino-4-hydroxypyrimidine Sulfate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D416355-2g |
2,6-Diamino-4-hydroxypyrimidine Sulfate |
58470-85-2 | 2g |
$104.00 | 2023-05-18 | ||
| TRC | D416355-5g |
2,6-Diamino-4-hydroxypyrimidine Sulfate |
58470-85-2 | 5g |
$173.00 | 2023-05-18 | ||
| TRC | D416355-10g |
2,6-Diamino-4-hydroxypyrimidine Sulfate |
58470-85-2 | 10g |
$305.00 | 2023-05-18 | ||
| TRC | D416355-25g |
2,6-Diamino-4-hydroxypyrimidine Sulfate |
58470-85-2 | 25g |
$ 595.00 | 2022-06-05 | ||
| TRC | D416355-50g |
2,6-Diamino-4-hydroxypyrimidine Sulfate |
58470-85-2 | 50g |
$1326.00 | 2023-05-18 | ||
| TRC | D416355-25000mg |
2,6-Diamino-4-hydroxypyrimidine Sulfate |
58470-85-2 | 25g |
$718.00 | 2023-05-18 | ||
| eNovation Chemicals LLC | Y0976862-5g |
4,6-diaminopyrimidin-2-ol |
58470-85-2 | 95% | 5g |
$625 | 2024-08-03 | |
| eNovation Chemicals LLC | Y0976862-5g |
4,6-diaminopyrimidin-2-ol |
58470-85-2 | 95% | 5g |
$625 | 2025-02-25 | |
| eNovation Chemicals LLC | Y0976862-5g |
4,6-diaminopyrimidin-2-ol |
58470-85-2 | 95% | 5g |
$625 | 2025-02-28 |
2,6-Diamino-4-hydroxypyrimidine Sulfate Related Literature
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J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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5. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
Additional information on 2,6-Diamino-4-hydroxypyrimidine Sulfate
Introduction to 2,6-Diamino-4-hydroxypyrimidine Sulfate (CAS No: 58470-85-2)
2,6-Diamino-4-hydroxypyrimidine Sulfate is a significant compound in the field of pharmaceutical chemistry and biochemistry, widely recognized for its versatile applications in drug development and research. With the CAS number 58470-85-2, this chemical has garnered attention due to its structural properties and potential biological activities. This introduction aims to provide a comprehensive overview of the compound, its chemical characteristics, and its relevance in contemporary scientific research.
The molecular structure of 2,6-Diamino-4-hydroxypyrimidine Sulfate consists of a pyrimidine core substituted with amino and hydroxyl groups, making it a valuable intermediate in synthesizing various pharmacologically active molecules. The sulfate salt form enhances its solubility in aqueous solutions, which is a critical factor for its use in biochemical assays and drug formulations.
In recent years, 2,6-Diamino-4-hydroxypyrimidine Sulfate has been extensively studied for its role in the development of antiviral and anticancer agents. Its ability to interact with nucleic acids and enzymes has opened new avenues in medicinal chemistry. For instance, researchers have explored its derivatives as potential inhibitors of viral polymerases and as components in targeted cancer therapies.
One of the most compelling aspects of 2,6-Diamino-4-hydroxypyrimidine Sulfate is its participation in the synthesis of nucleoside analogs. These analogs are crucial in antiviral drugs, where they mimic natural nucleosides but are structurally modified to inhibit viral replication. The compound’s dual amino and hydroxyl functionalities allow for diverse chemical modifications, enabling the creation of novel molecules with enhanced therapeutic profiles.
Current research highlights the compound’s potential in developing treatments for genetic disorders. By serving as a precursor for nucleotide-based therapies, 2,6-Diamino-4-hydroxypyrimidine Sulfate contributes to advancements in gene editing and repair technologies. Its stability under various pH conditions makes it an ideal candidate for formulations intended for oral or intravenous administration.
The industrial significance of 2,6-Diamino-4-hydroxypyrimidine Sulfate extends beyond pharmaceuticals. It is also utilized in agrochemicals as a building block for herbicides and fungicides. The compound’s ability to disrupt metabolic pathways in pests and weeds underscores its versatility in chemical applications.
From a synthetic chemistry perspective, 2,6-Diamino-4-hydroxypyrimidine Sulfate offers a scaffold that can be modified through various reactions such as condensation, alkylation, and acylation. These modifications lead to a wide array of derivatives with distinct biological activities. For example, certain derivatives have shown promise as kinase inhibitors, which are pivotal in treating cancers and inflammatory diseases.
The compound’s role in diagnostic imaging cannot be overlooked either. Researchers have incorporated derivatives of 2,6-Diamino-4-hydroxypyrimidine Sulfate into contrast agents used in magnetic resonance imaging (MRI). These agents enhance the visibility of tumors and other pathological conditions, aiding in early detection and more accurate diagnosis.
Eco-friendly considerations have also driven interest in 2,6-Diamino-4-hydroxypyrimidine Sulfate. Efforts are underway to develop sustainable synthetic routes that minimize waste and reduce environmental impact. Green chemistry principles are being applied to optimize production processes, ensuring that the compound remains accessible for research without compromising ecological standards.
The future prospects of 2,6-Diamino-4-hydroxypyrimidine Sulfate are promising, with ongoing studies exploring its applications in nanotechnology and materials science. Its unique chemical properties make it suitable for developing novel materials with applications ranging from electronics to biodegradable polymers.
In conclusion, 2,6-Diamino-4-hydroxypyrimidine Sulfate (CAS No: 58470-85-2) stands as a cornerstone compound in modern chemistry. Its broad utility spans pharmaceuticals, diagnostics, agriculture, and materials science. As research continues to uncover new applications and refine synthetic methodologies, this compound will undoubtedly remain at the forefront of scientific innovation.
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