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• 2. An integrated system for field analysis of Cd(ii) and Pb(ii) via preconcentration using nano-TiO2/cellulose paper composite and subsequent detection with a portable X-ray fluorescence spectrometer?
  Xiaofeng Lin RSC Adv., 2016,6, 9002-9006
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Comprehensive Overview of 1-(5-chlorothiophen-3-yl)ethan-1-one (CAS No. 58119-67-8): Properties, Applications, and Industry Insights

1-(5-chlorothiophen-3-yl)ethan-1-one (CAS 58119-67-8), a specialized organic compound featuring a chlorothiophene backbone, has garnered significant attention in pharmaceutical and agrochemical research. This ketone derivative exhibits unique electronic properties due to the synergistic effect of the chloro-substituent and thiophene ring, making it valuable for designing advanced materials. Recent studies highlight its role as a precursor in synthesizing heterocyclic compounds, particularly in developing crop protection agents and pharmaceutical intermediates.

The compound's molecular structure (C6H5ClOS) combines a 5-chlorothiophene-3-yl group with an acetyl moiety, creating a versatile scaffold for cross-coupling reactions. Industry reports indicate growing demand for such halogenated thiophene derivatives in organic electronics, where they contribute to improved charge transport in OLED materials. Analytical techniques like HPLC and GC-MS confirm its high purity (>98%), a critical parameter for researchers investigating structure-activity relationships in medicinal chemistry.

Environmental considerations surrounding chlorinated compounds have led to innovations in sustainable synthesis methods for 58119-67-8. A 2023 study demonstrated a catalyst-free approach using green solvents, aligning with the pharmaceutical industry's push toward green chemistry principles. This development addresses frequent search queries about "eco-friendly synthesis of thiophene derivatives" and "biodegradable intermediates," reflecting market trends toward sustainable production.

In material science applications, the electron-withdrawing character of the chloro group in 1-(5-chlorothiophen-3-yl)ethan-1-one enhances its utility in designing conductive polymers. Patent analyses reveal its incorporation in organic semiconductors for flexible electronics, responding to industry demands for wearable technology materials. These applications correlate with trending searches for "thiophene-based electronic materials" and "small molecule organic semiconductors."

Quality control protocols for CAS 58119-67-8 emphasize rigorous spectroscopic characterization, including 1H/13C NMR and FTIR analysis. Recent advancements in process analytical technology (PAT) enable real-time monitoring during production, ensuring batch-to-batch consistency—a key concern for manufacturers addressing queries about "purity standards for research chemicals." The compound's stability profile under various storage conditions (2-8°C in amber glass) makes it suitable for global distribution networks.

Emerging research explores the compound's potential in photocatalysis and energy storage systems, with particular interest in its redox-active properties. A 2024 publication highlighted its modified derivatives as components in next-generation battery materials, coinciding with increased searches for "organic electrode materials." This interdisciplinary applicability positions 1-(5-chlorothiophen-3-yl)ethan-1-one as a compound of interest across multiple high-growth sectors.

Regulatory compliance remains paramount when handling this compound. While not classified as hazardous under current GHS standards, proper laboratory safety protocols should be followed. Industry best practices recommend engineering controls and personal protective equipment (PPE) during handling, addressing common workplace safety queries related to specialty chemical handling.

The global market for chlorothiophene derivatives like 58119-67-8 is projected to grow at 6.2% CAGR through 2030, driven by demand from Asia-Pacific pharmaceutical hubs. Supply chain analytics indicate increasing preference for just-in-time manufacturing of such intermediates, reflecting industry responses to searches about "reliable specialty chemical suppliers." Technical specifications typically require residual solvent levels below 0.1% and heavy metal content under 10 ppm.

Future research directions focus on expanding the compound's utility through click chemistry modifications and bioconjugation techniques. Recent conferences have highlighted its potential in developing theranostic agents, merging diagnostic and therapeutic functions—a hot topic in searches for "multifunctional pharmaceutical building blocks." These developments underscore the compound's evolving role in cutting-edge chemical innovation.

• 57248-15-4(Methanone, bis(2,5-dichloro-3-thienyl)-)
• 36155-85-8(5-Chlorothiophene-3-carbaldehyde)
• 32427-80-8(1-(5-chlorothiophen-3-yl)propan-1-one)
• 36157-40-1(1-(2,5-dichlorothiophen-3-yl)ethan-1-one)
• 33527-28-5(4H,8H-Benzo[1,2-c:4,5-c']dithiophene-4,8-dione,1,3-dichloro-)
• 204844-98-4(Methanone, (2,5-dichloro-3-thienyl)(4-methylphenyl)-)
• 113399-19-2(Ethanone, 2-amino-1-(5-chloro-3-thienyl)-, hydrochloride)
• 99971-87-6((2,5-Dichlorothiophen-3-yl)(phenyl)methanone)
• 69213-95-2(ETHANONE, 1-(2,5-DICHLORO-4-METHYL-3-THIENYL)-)
• 81557-66-6(1-(2-Chlorothiophen-3-yl)ethanone)