Cas no 580-15-4 (6-Aminoquinoline)

6-Aminoquinoline is a heterocyclic organic compound featuring an amino group at the 6-position of the quinoline ring. This structural motif imparts significant utility in pharmaceutical and materials chemistry, serving as a versatile intermediate in the synthesis of bioactive molecules, including antimalarial and anticancer agents. Its electron-rich aromatic system and nucleophilic amino group enable diverse functionalization, making it valuable for constructing complex molecular architectures. The compound exhibits favorable solubility in common organic solvents, facilitating its use in synthetic applications. Additionally, its stability under standard conditions ensures reliable handling and storage. 6-Aminoquinoline is widely employed in research and industrial settings for developing novel therapeutic and functional materials.
6-Aminoquinoline structure
6-Aminoquinoline structure
Product Name:6-Aminoquinoline
CAS No:580-15-4
MF:C9H8N2
MW:144.173221588135
MDL:MFCD00006803
CID:38466
PubChem ID:24856657
Update Time:2025-05-21

6-Aminoquinoline Chemical and Physical Properties

Names and Identifiers

    • 6-Aminoquinoline
    • 6-Aminoquinoline,(6-Quinolinamine)
    • Quinolin-6-amine
    • 6-Amine-quinoline
    • 6-Quinolinamine
    • FT-0620944
    • XN7T264NL4
    • SY021131
    • Z255114686
    • DTXSID80206725
    • BDBM32026
    • EINECS 209-453-0
    • ES5
    • BB 0221206
    • quinolin-6-yl amine
    • NSC-58388
    • quinoline-6-amine
    • BIDD:GT0636
    • NSC 58388
    • AC-907/25014243
    • CHEMBL99408
    • MFCD00006803
    • NS00033833
    • MLS000080747
    • 6-amino quinoline
    • J-015670
    • W-105419
    • A18930
    • HY-W007404
    • Q27460051
    • NSC58388
    • SMR000036663
    • Quinolin-6-ylamine
    • (Ziprasidone Impurity B)
    • CS-W007404
    • 6-quinolylamine
    • 580-15-4
    • F2190-0533
    • SB67524
    • CCRIS 1681
    • US8546389, 98
    • HMS2451C16
    • PS-4529
    • 6-Amino-quinoline
    • SCHEMBL12280915
    • EN300-41836
    • Quinoline, 6-amino-
    • cid_11373
    • AC-4708
    • 3kqp
    • AKOS000131287
    • A1370
    • AM20061341
    • 6-Aminoquinoline, 98%
    • SCHEMBL160217
    • 6-Aminoquinoline,97%
    • Quinoline, 6-amino-(8CI)
    • DTXCID10129216
    • ALBB-014510
    • STK328120
    • DB-031615
    • FA00884
    • MDL: MFCD00006803
    • Inchi: 1S/C9H8N2/c10-8-3-4-9-7(6-8)2-1-5-11-9/h1-6H,10H2
    • InChI Key: RJSRSRITMWVIQT-UHFFFAOYSA-N
    • SMILES: N1C=CC=C2C=C(C=CC=12)N
    • BRN: 113320

Computed Properties

  • Exact Mass: 144.06900
  • Monoisotopic Mass: 144.068748
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 136
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 38.9

Experimental Properties

  • Color/Form: Powder
  • Density: 1.1148 (estimate)
  • Melting Point: 114.0 to 118.0 deg-C
  • Boiling Point: 187°C/11mmHg(lit.)
  • Flash Point: 146°C/0.3mm
  • Refractive Index: 1.7080 (estimate)
  • Water Partition Coefficient: Soluble in methanol, chloroform, ethanol, and benzene. Insoluble in water.
  • PSA: 38.91000
  • LogP: 2.39820
  • Sensitiveness: Air Sensitive
  • FEMA: 2132
  • Solubility: Soluble in ethanol, ether and ammonia, slightly soluble in water and petroleum.

6-Aminoquinoline Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H315,H319
  • Warning Statement: P305+P351+P338
  • Hazardous Material transportation number:2811
  • WGK Germany:3
  • Hazard Category Code: 36/38
  • Safety Instruction: S26-S36-S36/37/39
  • FLUKA BRAND F CODES:2-10
  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT, AIR SENSITIVE
  • PackingGroup:III
  • Storage Condition:Keep in dark place,Inert atmosphere,Room temperature
  • Safety Term:S26;S36/37/39
  • Packing Group:III
  • Packing Group:III
  • Risk Phrases:R20/21/22; R36/37/38

6-Aminoquinoline Customs Data

  • HS CODE:2933499090
  • Customs Data:

    China Customs Code:

    2933499090

    Overview:

    2933499090. Other compounds containing quinoline or isoquinoline ring system [but not further fused]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

6-Aminoquinoline Pricemore >>

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6-Aminoquinoline Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:580-15-4)6-Aminoquinoline
Order Number:A18930
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:01
Price ($):489.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:580-15-4)6-氨基喹啉
Order Number:LE1712500
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:35
Price ($):discuss personally

6-Aminoquinoline Related Literature

  • 1. The synthesis of a dinuclear anionic carbonyl derivative of manganese, [N(PPh3)2][Mn2(μ-PPh2)(CO)8], and its reactions with complexes of Group 1B and Group 8A metals to give mixed-metal clusters: comparative study of the X-ray crystal structures of [N(PPh3)2][Mn2(μ-PPh2)(CO)8], [Mn2{μ-Au(PMe2Ph)}(μ-PPh2)(CO)8], and [Mn2(μ-H)(μ-PPh2)(CO)8]
    Jonathan A. Iggo,Martin J. Mays,Paul R. Raithby,Kim Henrick J. Chem. Soc. Dalton Trans. 1984 633
  • 2. Quadridentate versus quinquedentate co-ordination of some N5 and N3O2 macrocyclic ligands and an unusual thermally controlled quintet ? singlet spin transition in an iron(II) complex
    S. Martin Nelson,Paul D. A. McIlroy,Clarke S. Stevenson,Edgar K?nig,Gerhard Ritter,Joachim Waigel J. Chem. Soc. Dalton Trans. 1986 991

Additional information on 6-Aminoquinoline

6-Aminoquinoline: A Comprehensive Overview

6-Aminoquinoline, also known by its CAS number CAS No. 580-15-4, is a heterocyclic organic compound that has garnered significant attention in various scientific and industrial fields. This compound, with the molecular formula C9H7N3, belongs to the quinoline family and is characterized by its unique chemical structure and versatile applications.

The structure of 6-Aminoquinoline consists of a quinoline ring with an amino group (-NH2) attached at the sixth position. This positioning imparts distinct chemical properties, making it a valuable intermediate in organic synthesis. The compound is widely used in the pharmaceutical industry, particularly in the development of antimalarial drugs, due to its ability to interact with specific biological targets.

Recent advancements in synthetic chemistry have led to innovative methods for the production of 6-Aminoquinoline. Researchers have explored various catalysts and reaction conditions to optimize its synthesis, ensuring higher yields and improved purity. These developments have not only enhanced the efficiency of production but also opened new avenues for its application in advanced materials science.

In the field of materials science, 6-Aminoquinoline has been utilized as a precursor for the synthesis of conductive polymers and metal-organic frameworks (MOFs). Its ability to coordinate with metal ions makes it an ideal candidate for constructing porous materials with applications in gas storage and catalysis. Furthermore, studies have shown that 6-Aminoquinoline-based MOFs exhibit exceptional stability under harsh conditions, making them suitable for industrial applications.

The biological activity of 6-Aminoquinoline has also been a focal point of recent research. Scientists have investigated its potential as an antimicrobial agent, particularly against drug-resistant bacterial strains. Experimental results indicate that 6-Aminoquinoline derivatives can inhibit bacterial growth by disrupting cellular membranes, offering a promising solution to the global challenge of antibiotic resistance.

In addition to its pharmacological applications, 6-Aminoquinoline has found utility in analytical chemistry as a fluorescent probe for detecting metal ions in aqueous solutions. Its fluorescence properties are highly sensitive to environmental changes, enabling precise detection of contaminants such as heavy metals in water samples.

The demand for CAS No. 580-15-4-based compounds continues to grow across multiple industries due to their versatility and adaptability. As researchers delve deeper into understanding the compound's properties, new applications are expected to emerge, further solidifying its role in modern science and technology.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:580-15-4)6-Aminoquinoline
A18930
Purity:99%
Quantity:500g
Price ($):489.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:580-15-4)6-氨基喹啉
LE1712500
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email