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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

Introduction to L(+)-Asparagine Monohydrate (CAS No. 5794-13-8)

L(+)-Asparagine monohydrate, with the chemical formula C?H?NO?·H?O, is a widely recognized compound in the field of pharmaceuticals, biotechnology, and food science. This zwitterionic amino acid, specifically the L-form, is the enantiomer that is naturally occurring and biologically active in humans and many other organisms. The presence of a monohydrate form indicates that each molecule of asparagine is associated with one water molecule, which can influence its solubility, stability, and reactivity. As a result of its significance in biological processes and industrial applications, L(+)-Asparagine monohydrate has garnered considerable attention in recent years.

The compound is primarily utilized as a building block in the synthesis of peptides and proteins due to its role as a non-essential amino acid. It is also employed in various research applications, including enzyme kinetics studies, metabolic pathways analysis, and as a supplement in cell culture media. The hydrate form enhances the compound's solubility in aqueous solutions, making it particularly useful for laboratory experiments and large-scale industrial processes.

In recent years, L(+)-Asparagine monohydrate has been the subject of numerous studies aimed at exploring its potential therapeutic applications. One of the most promising areas of research is its role in cancer therapy. Studies have shown that asparagine deprivation can selectively starve tumor cells, which rely heavily on this amino acid for growth and proliferation. This concept has led to the development of novel therapeutic strategies that target asparaginase enzymes, which catalyze the hydrolysis of asparagine into aspartic acid and ammonia.

Moreover, L(+)-Asparagine monohydrate has been investigated for its potential benefits in the field of regenerative medicine. Research indicates that it can support tissue repair and wound healing by providing essential nutrients to cells and promoting the synthesis of extracellular matrix components. This has opened up new avenues for developing advanced wound care products and tissue engineering scaffolds.

The food industry also benefits from L(+)-Asparagine monohydrate due to its role as a flavor enhancer and nutrient supplement. It is commonly added to infant formulas, sports supplements, and other specialized dietary products to improve nutritional value and taste profile. Its stability under various processing conditions makes it an ideal candidate for use in food formulations where consistency and purity are paramount.

Recent advancements in analytical chemistry have further highlighted the importance of L(+)-Asparagine monohydrate in quality control processes. High-performance liquid chromatography (HPLC) and mass spectrometry (MS) techniques have enabled researchers to accurately determine the purity and concentration of this compound in complex mixtures. These methods are crucial for ensuring that pharmaceutical products meet stringent regulatory standards before they reach the market.

The synthesis of L(+)-Asparagine monohydrate has also seen significant improvements over the years. Traditional methods often relied on enzymatic hydrolysis or chemical synthesis from precursor molecules like aspartic acid or mesaconic acid. However, newer approaches have focused on more sustainable and cost-effective production techniques. For instance, fermentation processes using genetically modified microorganisms have been developed to produce high-purity L(+)-Asparagine monohydrate on an industrial scale.

The impact of L(+)-Asparagine monohydrate extends beyond its direct applications into broader scientific fields such as bioinformatics and systems biology. By understanding how this amino acid interacts with other molecules within cellular environments, researchers can gain insights into complex biological pathways and disease mechanisms. This knowledge is invaluable for developing targeted therapies and personalized medicine approaches.

In conclusion, L(+)-Asparagine monohydrate (CAS No. 5794-13-8) is a multifaceted compound with diverse applications across multiple industries. Its role in pharmaceuticals, biotechnology, food science, and research underscores its importance as a key component in modern science and industry. As research continues to uncover new uses for this compound, its significance is likely to grow even further.

• 2058-58-4(D-Asparagine)
• 70-47-3(L-Asparagine)
• 28088-48-4(L-Asparagine,homopolymer)
• 287484-30-4(L-Asparagine-N2-15N,monohydrate (9CI))
• 3130-87-8(DL-2-Aminosuccinamic acid)
• 5794-24-1(D-(-)-Asparagine Monohydrate)
• 69833-18-7(DL-Asparagine Monohydrate)
• 287484-32-6(L-Asparagine-15N2 Hydrate)
• 204451-47-8(L-Asparagine-(amide-15N) monohydrate)
• 51546-95-3(Palladium,bis(L-asparaginato-N2,O1)- (9CI))