Cas no 57757-66-1 (N-[3-(Trimethoxysilyl)propyl]acetamide)

N-[3-(Trimethoxysilyl)propyl]acetamide is a silane coupling agent with a reactive trimethoxysilyl group and an acetamide functional group. This compound is particularly useful in surface modification and adhesion promotion, offering strong bonding between organic polymers and inorganic substrates. Its hydrolyzable methoxy groups enable covalent bonding to hydroxylated surfaces, while the acetamide moiety provides compatibility with organic matrices. The product is valued for its stability, moisture resistance, and ability to enhance interfacial adhesion in composites, coatings, and sealants. Its bifunctional nature makes it suitable for applications requiring durable surface treatment and improved mechanical properties in hybrid material systems.
N-[3-(Trimethoxysilyl)propyl]acetamide structure
57757-66-1 structure
Product Name:N-[3-(Trimethoxysilyl)propyl]acetamide
CAS No:57757-66-1
MF:C8H19NO4Si
MW:221.3263
MDL:MFCD09910164
CID:947502
PubChem ID:21242003
Update Time:2025-05-25

N-[3-(Trimethoxysilyl)propyl]acetamide Chemical and Physical Properties

Names and Identifiers

    • ACETAMIDOPROPYLTRIMETHOXYSILANE
    • 3-Acetamidopropyl Trimethoxysilane
    • (3-ACETAMIDOPROPYL)TRIMETHOXYSILANE
    • N-(3-trimethoxysilylpropyl)acetamide
    • N-((dimethoxy(propyl)silyloxy)methyl)acetamide
    • N-[3-(Trimethoxysilyl)propyl]acetamide
    • N-(3-(trimethoxysilyl)propyl)acetamide
    • SCHEMBL960689
    • 57757-66-1
    • DB-318525
    • CS-0453746
    • DTXSID30611562
    • MFCD09910164
    • G70192
    • MDL: MFCD09910164
    • Inchi: 1S/C8H19NO4Si/c1-8(10)9-6-5-7-14(11-2,12-3)13-4/h5-7H2,1-4H3,(H,9,10)
    • InChI Key: JXLQREJGIDQFJP-UHFFFAOYSA-N
    • SMILES: [Si](C([H])([H])C([H])([H])C([H])([H])N([H])C(C([H])([H])[H])=O)(OC([H])([H])[H])(OC([H])([H])[H])OC([H])([H])[H]

Computed Properties

  • Exact Mass: 221.10800
  • Monoisotopic Mass: 221.108335g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 7
  • Complexity: 165
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 56.8
  • Molecular Weight: 221.33g/mol

Experimental Properties

  • Color/Form: No data avaiable
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 162-5°C/2-3mmHg
  • Flash Point: 126.8±22.6 °C
  • Refractive Index: 1.441
  • PSA: 56.79000
  • LogP: 0.78160
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

N-[3-(Trimethoxysilyl)propyl]acetamide Security Information

N-[3-(Trimethoxysilyl)propyl]acetamide Pricemore >>

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Additional information on N-[3-(Trimethoxysilyl)propyl]acetamide

N-[3-(Trimethoxysilyl)propyl]acetamide: A Comprehensive Overview

N-[3-(Trimethoxysilyl)propyl]acetamide, also known by its CAS number 57757-66-1, is a compound that has garnered significant attention in various scientific and industrial fields. This compound is a derivative of acetamide, with a trimethoxysilyl group attached to the propyl chain. The structure of this compound is characterized by a silyl ether group (-Si(OCH3)3), which plays a crucial role in its chemical reactivity and functional properties.

The synthesis of N-[3-(Trimethoxysilyl)propyl]acetamide involves the reaction of trimethoxysilane with an appropriate propyl chain derivative, followed by acetylation to introduce the acetamide group. This process ensures the formation of a stable and versatile compound that can be tailored for specific applications. Recent studies have highlighted the potential of this compound in material science, particularly in the development of advanced coatings and adhesives.

One of the key features of N-[3-(Trimethoxysilyl)propyl]acetamide is its ability to undergo hydrolysis under certain conditions, leading to the formation of silanol groups (-SiOH). These groups are highly reactive and can participate in various chemical reactions, including condensation reactions, which are essential for forming cross-linked networks. This property makes the compound an ideal candidate for use in silicone-based materials, where cross-linking is critical for achieving desired mechanical and thermal properties.

In addition to its role in material science, N-[3-(Trimethoxysilyl)propyl]acetamide has also found applications in biotechnology and pharmaceuticals. The trimethoxysilyl group imparts unique bioactive properties to the compound, making it suitable for use in drug delivery systems and biomedical implants. Recent research has explored the potential of this compound as a bioactive agent that can enhance cell adhesion and proliferation on implant surfaces, thereby improving the success rate of medical devices.

The versatility of N-[3-(Trimethoxysilyl)propyl]acetamide extends to its use in polymer chemistry. By incorporating this compound into polymer matrices, researchers have been able to develop materials with enhanced mechanical strength, thermal stability, and resistance to environmental factors such as moisture and UV radiation. These properties make it an attractive option for applications in aerospace, automotive industries, and electronic packaging.

From an environmental perspective, N-[3-(Trimethoxysilyl)propyl]acetamide has been studied for its biodegradability and eco-friendly characteristics. Recent advancements have focused on optimizing the synthesis process to minimize waste and energy consumption, aligning with global sustainability goals. The compound's ability to degrade under specific conditions makes it a promising alternative to traditional materials that are less environmentally friendly.

In conclusion, N-[3-(Trimethoxysilyl)propyl]acetamide (CAS No: 57757-66-1) is a multifaceted compound with a wide range of applications across diverse industries. Its unique chemical structure, reactivity, and functional properties continue to drive innovation in material science, biotechnology, and polymer chemistry. As research progresses, this compound is expected to play an increasingly important role in developing advanced materials and technologies that address contemporary challenges.

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