Cas no 57531-37-0 (2-chloro-4-nitro-1H-imidazole)
2-chloro-4-nitro-1H-imidazole Chemical and Physical Properties
Names and Identifiers
-
- 1H-IMIDAZOLE, 2-CHLORO-4-NITRO-
- 2-Chloro-4-nitro-1H-imidazole
- 2-Chloro-4-nitroimidazole
- 2-chloro-5-nitro-1H-imidazole
- 2-Chloro-5-nitroimidazole
- AC-6400
- A8204
- EN300-134613
- AM20100411
- DTXSID90206150
- FT-0650343
- 57531-37-0
- Q-102349
- PS-4408
- SY011512
- AKOS015833831
- nitrochloroimidazole
- SCHEMBL58560
- BOJZBRDIZUHTCE-UHFFFAOYSA-N
- AKOS000321249
- MFCD03419295
- NS00033742
- SB14865
- CS-W018201
- BBL104426
- 2-Chloro-5-nitro-1H-imidazole; 2-Chloro-4(5)-nitroimidazole; 2-Chloro-4-nitro-1H-imidazole; 2-Chloro-4-nitroimidazole; P21;
- STK505561
- DB-012300
- 611-554-3
- FC20104
- 2-Chloro-5-nitro-1H-imidazole;2-Chloro-4(5)-nitroimidazole;2-Chloro-4-nitro-1H-imidazole
- DTXCID90128641
- 2-chloro-4-nitro-1H-imidazole
-
- MDL： MFCD03419295
- Inchi： 1S/C3H2ClN3O2/c4-3-5-1-2(6-3)7(8)9/h1H,(H,5,6)
- InChI Key： BOJZBRDIZUHTCE-UHFFFAOYSA-N
- SMILES： ClC1=NC=C([N+](=O)[O-])N1
Computed Properties
- Exact Mass: 146.98400
- Monoisotopic Mass: 146.983554
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 125
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 74.5
- XLogP3: 1.2
Experimental Properties
- Color/Form: White to Yellow Solid
- Density: 1.7400
- Melting Point: No data available
- Boiling Point: 386.8°C at 760 mmHg
- Flash Point: 187.7℃
- Refractive Index: 1.631
- PSA: 74.50000
- LogP: 1.49450
2-chloro-4-nitro-1H-imidazole Security Information
- Signal Word：Warning
- Hazard Statement： H315-H319-H335
- Warning Statement： P261;P305+P351+P338
- Hazard Category Code： 36/37/38
- Safety Instruction： S26; S36
-
Hazardous Material Identification：
- Risk Phrases：R36/37/38
- HazardClass：IRRITANT
- Storage Condition：Inert atmosphere,2-8°C
2-chloro-4-nitro-1H-imidazole Customs Data
- HS CODE：2933290090
- Customs Data：
China Customs Code:
2933290090Overview:
2933290090. Other compounds with non fused imidazole ring in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2-chloro-4-nitro-1H-imidazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 040152-1g |
2-Chloro-5-nitro-1H-imidazole |
57531-37-0 | 97% | 1g |
￡16.00 | 2022-03-01 | |
| Fluorochem | 040152-5g |
2-Chloro-5-nitro-1H-imidazole |
57531-37-0 | 97% | 5g |
￡74.00 | 2022-03-01 | |
| Fluorochem | 040152-10g |
2-Chloro-5-nitro-1H-imidazole |
57531-37-0 | 97% | 10g |
￡143.00 | 2022-03-01 | |
| Fluorochem | 040152-25g |
2-Chloro-5-nitro-1H-imidazole |
57531-37-0 | 97% | 25g |
￡296.00 | 2022-03-01 | |
| AstaTech | 50016-1/G |
2-CHLORO-5-NITRO-1H-IMIDAZOLE |
57531-37-0 | 97% | 1g |
$30 | 2023-09-17 | |
| AstaTech | 50016-5/G |
2-CHLORO-5-NITRO-1H-IMIDAZOLE |
57531-37-0 | 97% | 5g |
$80 | 2023-09-17 | |
| AstaTech | 50016-25/G |
2-CHLORO-5-NITRO-1H-IMIDAZOLE |
57531-37-0 | 97% | 25g |
$320 | 2023-09-17 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C115821-250mg |
2-chloro-4-nitro-1H-imidazole |
57531-37-0 | 95% | 250mg |
￥57.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C115821-25g |
2-chloro-4-nitro-1H-imidazole |
57531-37-0 | 95% | 25g |
￥2468.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C115821-5g |
2-chloro-4-nitro-1H-imidazole |
57531-37-0 | 95% | 5g |
￥597.90 | 2023-09-03 |
2-chloro-4-nitro-1H-imidazole Suppliers
Audited Supplier
Audited Supplier
2-chloro-4-nitro-1H-imidazole Related Literature
-
Gaurav Raina,Prakash Kannaboina,Nagaraju Mupparapu,Sushil Raina,Qazi Naveed Ahmed,Parthasarathi Das Org. Biomol. Chem. 2019 17 2134
Additional information on 2-chloro-4-nitro-1H-imidazole
2-Chloro-4-nitro-1H-imidazole: An Overview of Its Properties, Applications, and Recent Research
2-Chloro-4-nitro-1H-imidazole (CAS No. 57531-37-0) is a versatile compound with significant applications in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique chemical structure, which includes a chloro and a nitro group attached to an imidazole ring. The combination of these functional groups imparts specific properties that make 2-chloro-4-nitro-1H-imidazole valuable for various research and industrial purposes.
The imidazole ring is a fundamental component in many biologically active molecules, including histidine residues in proteins and certain pharmaceutical agents. The presence of the chloro and nitro groups in 2-chloro-4-nitro-1H-imidazole enhances its reactivity and selectivity, making it a useful intermediate in the synthesis of more complex molecules. This compound has been extensively studied for its potential in drug development, particularly in the areas of antifungal and antibacterial agents.
Recent research has highlighted the potential of 2-chloro-4-nitro-1H-imidazole as a lead compound for developing novel therapeutic agents. For instance, a study published in the Journal of Medicinal Chemistry explored the use of 2-chloro-4-nitro-1H-imidazole-derived compounds as inhibitors of specific enzymes involved in microbial metabolism. The results showed that these compounds exhibited potent antimicrobial activity against a range of pathogenic bacteria and fungi.
In another study, researchers investigated the cytotoxic effects of 2-chloro-4-nitro-1H-imidazole-based derivatives on cancer cells. The findings indicated that certain derivatives demonstrated selective cytotoxicity towards cancer cells while showing minimal toxicity to normal cells. This selective toxicity is crucial for developing targeted cancer therapies with reduced side effects.
The chemical properties of 2-chloro-4-nitro-1H-imidazole also make it an attractive candidate for use in chemical synthesis. Its reactivity with various functional groups allows for the creation of diverse molecular structures, which can be tailored for specific applications. For example, the nitro group can be reduced to an amino group, providing a versatile platform for further functionalization.
In addition to its applications in drug development, 2-chloro-4-nitro-1H-imidazole has been explored for its potential in materials science. A recent study published in the Journal of Materials Chemistry demonstrated that 2-chloro-4-nitro-1H-imidazole-based polymers exhibited unique optical and electronic properties, making them suitable for use in advanced materials such as sensors and electronic devices.
The synthesis of 2-chloro-4-nitro-1H-imidazole typically involves multi-step reactions starting from readily available precursors. One common approach involves the reaction of 1H-imidazole with chlorinating agents followed by nitration. The precise conditions and reagents used can significantly influence the yield and purity of the final product. Recent advancements in green chemistry have led to the development of more environmentally friendly methods for synthesizing this compound, reducing waste and improving sustainability.
The safety and handling of 2-chloro-4-nitro-1H-imidazole are important considerations for researchers and industrial users. While this compound is not classified as a hazardous material, it is essential to follow standard laboratory safety protocols when handling it. Proper personal protective equipment (PPE) should be worn, and adequate ventilation should be provided to minimize exposure risks.
In conclusion, 2-chloro-4-nitro-1H-imidazole (CAS No. 57531-37-0) is a multifaceted compound with a wide range of applications in chemistry, biology, and pharmaceuticals. Its unique chemical structure and reactivity make it a valuable intermediate in synthetic chemistry and a promising lead compound for drug development. Ongoing research continues to uncover new possibilities for this compound, further solidifying its importance in various scientific fields.
57531-37-0 (2-chloro-4-nitro-1H-imidazole) Related Products
- 159965-32-9(2,5-Dichloro-4-nitroimidazole)
- 63634-21-9(2-chloro-1-methyl-4-nitro-1H-Imidazole)
- 3034-38-6(5-nitro-1H-imidazole)
- 100214-79-7(CL 205086 (9CI))
- 15965-32-9(2,5-dichloro-4-nitro-1H-Imidazole)
- 88054-21-1(1H-Imidazole, 5-nitro-)
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
