Cas no 57526-81-5 (Prenalterol)
Prenalterol Chemical and Physical Properties
Names and Identifiers
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- (S)-4-(2-Hydroxy-3-(isopropylamino)propoxy)phenol
- Prenalterol
- 4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenol
- (S)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenol
- (-)-Prenalterol
- (S)-Prenalterol
- CGP 7760B
- Hyprenan
- 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenol
- S-Varbian
- H 133
- DTXSID8023507
- Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)-
- Prenalterolum
- 4-[(2S)-2-hydroxy-3-(isopropylamino)propoxy]phenol
- Prenalterol is known as a beta1 adrenoreceptor agonist.
- CHEMBL1160714
- CS-0043280
- UNII-M4G34404CX
- PRENALTEROL [INN]
- (S)-4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)phenol
- Prenalterol [INN:BAN]
- (-)-(S)-1-(p-Hydroxyphenoxy)-3-(isopropylamino)-2-propanol
- C07533
- PHENOL METABOLITE
- Q7240518
- BRN 5740338
- BDBM50421716
- 57526-81-5
- EINECS 260-791-5
- PRENALTEROL [MI]
- (S)-1-(4-hydroxyphenoxy)-3-(1-methylethyl)amino-2-propanol
- SCHEMBL249753
- ADUKCCWBEDSMEB-NSHDSACASA-N
- DB13777
- PRENALTEROL [WHO-DD]
- CHEBI:8391
- GTPL537
- HY-112071
- Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
- M4G34404CX
- NS00033741
- Prenalterolum [INN-Latin]
- H 133/22
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- MDL： MFCD01707351
- Inchi： 1S/C12H19NO3/c1-9(2)13-7-11(15)8-16-12-5-3-10(14)4-6-12/h3-6,9,11,13-15H,7-8H2,1-2H3/t11-/m0/s1
- InChI Key： ADUKCCWBEDSMEB-NSHDSACASA-N
- SMILES： O(C1C=CC(=CC=1)O)C[C@H](CNC(C)C)O
Computed Properties
- Exact Mass: 225.13600
- Monoisotopic Mass: 225.136493
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 16
- Rotatable Bond Count: 6
- Complexity: 179
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.4
- Topological Polar Surface Area: 61.7
Experimental Properties
- Density: 1.118
- Melting Point: 127-128°
- Boiling Point: 398 oC
- Flash Point: 194 oC
- Refractive Index: 1.538
- Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
- PSA: 61.72000
- LogP: 1.52080
- Specific Rotation: D20 -1 ±1°; 20Hg +2 ±1° (c = 0.940 in methanol)
- Vapor Pressure: 0.0±1.0 mmHg at 25°C
Prenalterol Security Information
- Signal Word：warning
- Hazard Statement： H303+H313+H333
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：Refrigerator
Prenalterol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | P712700-10mg |
Prenalterol |
57526-81-5 | 10mg |
$ 150.00 | 2023-09-06 | ||
| TRC | P712700-25mg |
Prenalterol |
57526-81-5 | 25mg |
$ 230.00 | 2023-09-06 | ||
| TRC | P712700-50mg |
Prenalterol |
57526-81-5 | 50mg |
$ 431.00 | 2023-09-06 | ||
| TRC | P712700-100mg |
Prenalterol |
57526-81-5 | 100mg |
$781.00 | 2023-05-17 | ||
| TRC | P712700-250mg |
Prenalterol |
57526-81-5 | 250mg |
$1774.00 | 2023-05-17 | ||
| eNovation Chemicals LLC | D553686-1g |
(S)-4-(2-Hydroxy-3-(isopropylaMino)propoxy)phenol |
57526-81-5 | 97% | 1g |
$1100 | 2024-05-24 | |
| SHENG KE LU SI SHENG WU JI SHU | sc-476624-2.5 mg |
Prenalterol-d7, |
57526-81-5 | 2.5 mg |
￥2,858.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-280023A-5 mg |
Prenalterol, |
57526-81-5 | ≥95% | 5mg |
￥1,008.00 | 2023-07-10 | |
| SHENG KE LU SI SHENG WU JI SHU | sc-280023-25 mg |
Prenalterol, |
57526-81-5 | ≥95% | 25mg |
￥3,761.00 | 2023-07-10 | |
| SHENG KE LU SI SHENG WU JI SHU | sc-280023A-5mg |
Prenalterol, |
57526-81-5 | ≥95% | 5mg |
￥1008.00 | 2023-09-05 |
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Prenalterol Related Literature
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Abdel-Aziz M. Wahbi,Mohamed E. Mohamed,El Rasheed A. Gad Kariem,Hassan Y. Aboul-Enein Analyst 1983 108 886
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2. Index pages
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3. Back matter
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4. Back matter
Additional information on Prenalterol
Comprehensive Overview of Prenalterol (CAS No. 57526-81-5): Pharmacology, Applications, and Research Insights
Prenalterol (CAS No. 57526-81-5) is a selective β1-adrenergic receptor agonist with significant pharmacological properties. This compound has garnered attention in cardiovascular research due to its ability to stimulate cardiac β1-receptors, leading to positive inotropic effects without significantly affecting heart rate. As a derivative of phenylethanolamine, Prenalterol exhibits unique therapeutic potential, particularly in conditions requiring enhanced myocardial contractility.
In recent years, the demand for cardiac stimulants like Prenalterol has surged, driven by the global rise in heart failure cases and the need for targeted therapies. Researchers and clinicians frequently search for "Prenalterol mechanism of action" or "β1-agonist clinical applications," reflecting growing interest in its precise pharmacological effects. The compound's ability to selectively activate β1-receptors distinguishes it from non-selective agonists, minimizing adverse effects such as tachycardia or hypertension.
The synthesis and characterization of Prenalterol (CAS No. 57526-81-5) involve advanced organic chemistry techniques, including chiral resolution to isolate its active enantiomer. This specificity is critical for optimizing its pharmacokinetic profile, a topic often queried in academic and pharmaceutical forums. Studies highlight its oral bioavailability and metabolic stability, making it a candidate for further drug development in cardiovascular medicine.
Beyond its primary use, Prenalterol has been explored in exercise physiology research, where its inotropic effects may benefit athletes with cardiomyopathy. However, ethical and regulatory discussions around performance-enhancing drugs have limited such applications. Searches like "Prenalterol in sports" or "β1-agonists and athletic performance" underscore this controversial yet scientifically intriguing angle.
From a molecular biology perspective, Prenalterol serves as a tool compound to study G-protein-coupled receptor (GPCR) signaling. Its binding affinity and selectivity for β1-adrenergic receptors are frequently compared to other agonists like dobutamine, a common query in pharmacology research. This comparative analysis aids in designing next-generation cardiotherapeutic agents with improved safety profiles.
Environmental and toxicological studies of Prenalterol (CAS No. 57526-81-5) confirm its low ecotoxicity, aligning with modern green chemistry principles. This aspect is increasingly relevant as the pharmaceutical industry prioritizes sustainable drug design. Queries such as "Prenalterol environmental impact" reflect this shift in consumer and regulatory priorities.
In summary, Prenalterol remains a compound of interest for its cardioselective properties and potential therapeutic applications. Ongoing research into its molecular interactions and clinical efficacy ensures its relevance in both academic and industrial settings. As the scientific community continues to explore precision medicine, compounds like Prenalterol exemplify the intersection of pharmacology and personalized healthcare.
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