• 1. An antimonate pyrochlore (H1.23Sr0.45SbO3.48) for photocatalytic oxidation of benzene: effective oxygen usage and excellent activity?
  Jing Chen,Yu Shao,Danzhen Li J. Mater. Chem. A, 2017,5, 937-941
• 2. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 3. Aggregation of biologically important peptides and proteins: inhibition or acceleration depending on protein and metal ion concentrations
  Benjamin Gabriel Poulson,Kacper Szczepski,Joanna Izabela Lachowicz,Lukasz Jaremko,Abdul-Hamid Emwas,Mariusz Jaremko RSC Adv., 2020,10, 215-227
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Pyrenes Benzopyrenes

Benzo[a]pyrene-9,10-diol: A Comprehensive Overview

Benzo[a]pyrene-9,10-diol, also known by its CAS number 57303-98-7, is a polycyclic aromatic hydrocarbon (PAH) derivative that has garnered significant attention in the scientific community due to its unique properties and potential applications. This compound is a dihydroxy derivative of benzo[a]pyrene, a well-known PAH with a fused aromatic ring system. The presence of the diol group introduces interesting chemical and biological properties, making it a subject of extensive research in various fields such as materials science, environmental chemistry, and pharmacology.

The structure of Benzo[a]pyrene-9,10-diol consists of a rigid planar framework with conjugated double bonds, which contributes to its strong fluorescence properties. This feature has made it a valuable tool in fluorescence-based sensing and imaging applications. Recent studies have explored the use of this compound as a fluorescent probe for detecting specific analytes in complex matrices, leveraging its high sensitivity and selectivity.

In terms of synthesis, researchers have developed various methods to efficiently produce Benzo[a]pyrene-9,10-diol. One notable approach involves the oxidation of benzo[a]pyrene using mild oxidizing agents under controlled conditions. This method ensures high yield and maintains the integrity of the aromatic system, which is crucial for preserving the compound's fluorescence properties.

The biological activity of Benzo[a]pyrene-9,10-diol has also been a focal point of recent investigations. Studies have shown that this compound exhibits potential anti-cancer properties by targeting specific pathways involved in tumor growth and metastasis. Preclinical trials have demonstrated its ability to inhibit the proliferation of cancer cells without significantly affecting normal cells, suggesting its potential as a novel therapeutic agent.

In environmental science, Benzo[a]pyrene-9,10-diol has been studied for its role in pollution monitoring. Due to its high sensitivity to environmental changes, it can serve as an indicator for assessing the presence of harmful pollutants in air and water samples. This application aligns with the growing need for effective environmental monitoring tools in the face of increasing industrialization.

The application of Benzo[a]pyrene-9,10-diol in nanotechnology is another emerging area of research. Its planar structure and strong fluorescence make it an ideal candidate for use in constructing nano-sized sensors and imaging agents. Recent advancements have utilized this compound to develop nanosensors capable of detecting heavy metals and other toxic substances at trace levels.

In conclusion, Benzo[a]pyrene-9,10-diol, with its CAS number 57303-98-7, stands out as a versatile compound with diverse applications across multiple disciplines. Its unique chemical properties and biological activity continue to drive innovative research, positioning it as a key player in advancing scientific knowledge and practical applications.

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