Cas no 5714-80-7 (D-Histidine Methyl Ester Dihydrochloride)

D-Histidine Methyl Ester Dihydrochloride is a chiral derivative of histidine, commonly utilized in peptide synthesis and biochemical research. Its methyl ester and dihydrochloride form enhances solubility and stability, facilitating handling in aqueous and organic solvents. The compound serves as a key intermediate in the preparation of modified peptides and enzyme substrates, offering precise stereochemical control due to its D-configuration. Its high purity and consistent performance make it suitable for applications in medicinal chemistry and proteomics. The dihydrochloride salt further improves reactivity, ensuring efficient coupling in solid-phase and solution-phase synthesis. This reagent is valued for its reliability in producing structurally defined peptides and bioactive molecules.
D-Histidine Methyl Ester Dihydrochloride structure
5714-80-7 structure
Product Name:D-Histidine Methyl Ester Dihydrochloride
CAS No:5714-80-7
MF:C4H10ClNO2S
MW:171.6456990242
MDL:MFCD00173915
CID:373166
PubChem ID:21951
Update Time:2025-06-14

D-Histidine Methyl Ester Dihydrochloride Chemical and Physical Properties

Names and Identifiers

    • Methyl 2-amino-3-mercaptopropionate hydrochloride
    • Cysteine, methyl ester,hydrochloride (1:1)
    • DL-CYSTEINE METHYL ESTER HYDROCHLORIDE
    • methyl 2-amino-3-sulfanylpropanoate,hydrochloride
    • METHYL DL-CYSTEINATE HYDROCHLORIDE
    • Cys-OMe*HCl
    • cysteine methyl ester hydrochloride
    • Cysteine,hydrochloride
    • hydrochloride of cysteine methylester
    • L-CYSTEINE METHYL ESTER
    • L-cysteine methylester hydrochloride
    • Mecystein HCl
    • Mecysteine hydrochloride
    • methionine methyl ester hydrochloride
    • methyl 2-amino-3-mercaptopropanoate hydrochloride
    • Methyl cysteine HCl
    • Methyl cysteine hydrochloride
    • Methyl2-amino-3-mercaptopropanoate,HCl
    • MFCD00672724
    • AM20100664
    • Epecoale hydrochloride
    • SY131689
    • Methyl2-amino-3-mercaptopropionatehydrochloride
    • methyl 2-amino-3-sulfanylpropanoate;hydrochloride
    • NCGC00094821-02
    • 5714-80-7
    • NSC-161611
    • methyl cysteinate hydrochloride
    • L.J. 48
    • DTXSID90972606
    • CHEMBL1490495
    • NSC161611
    • Methyl cysteinate--hydrogen chloride (1/1)
    • SY021999
    • BCP30482
    • Mecysteine hydrochloride pound>>Methyl cysteine hydrochloride ; Mecysteine HCl; NSC 161611; NSC161611; NSC-161611
    • (S)-Cysteine methyl ester hydrochloride; Methyl D-cysteinate hydrochloride
    • Zeotin
    • Methyl 2-amino-3-mercaptopropanoate hydrochloride (H-DL-Cys-OMe.HCl)
    • SY076955
    • methyl 2-amino-3-sulfanylpropanoate hydrochloride
    • D-Cysteine,methyl ester,hydrochloride(1:1)
    • Methyl 2-amino-3-mercaptopropanoate, HCl
    • CS-0150913
    • CCG-39983
    • AKOS008966901
    • NCGC00094821-01
    • Cysteine, methyl ester, hydrochloride (1:1)
    • Chistait
    • NSC757395
    • Cysteine, hydrochloride
    • NSC-757395
    • EINECS 227-208-6
    • H-D-Cys-OMe HCl
    • HMS1921M13
    • FT-0627751
    • MFCD00038985
    • Methyl .alpha.-amino-.beta.-mercaptopropionate hydrochloride
    • FT-0698872
    • SPECTRUM1500636
    • BS-17674
    • EN300-05974
    • SCHEMBL1445530
    • Pharmakon1600-01500636
    • H10905
    • Pectite
    • Methyl cysteine, hydrochloride
    • Cysteine, methyl ester, hydrochloride
    • Methyl .beta.-mercaptoalanine hydrochloride
    • MFCD00173915
    • DA-55384
    • Cysteine, methyl ester, hydrochloride (VAN)
    • DB-360663
    • WHOHXJZQBJXAKL-UHFFFAOYSA-N
    • DB-044575
    • D-Histidine Methyl Ester Dihydrochloride
    • MDL: MFCD00173915
    • Inchi: 1S/C4H9NO2S.ClH/c1-7-4(6)3(5)2-8;/h3,8H,2,5H2,1H3;1H
    • InChI Key: WHOHXJZQBJXAKL-UHFFFAOYSA-N
    • SMILES: Cl.SCC(C(=O)OC)N

Computed Properties

  • Exact Mass: 171.01200
  • Monoisotopic Mass: 171.012077
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 3
  • Complexity: 86.1
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 53.3

Experimental Properties

  • Boiling Point: 197.2°Cat760mmHg
  • Flash Point: 73.1°C
  • PSA: 91.12000
  • LogP: 0.91880

D-Histidine Methyl Ester Dihydrochloride Customs Data

  • HS CODE:2930909090
  • Customs Data:

    China Customs Code:

    2930909090

    Overview:

    2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

D-Histidine Methyl Ester Dihydrochloride Pricemore >>

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Additional information on D-Histidine Methyl Ester Dihydrochloride

Recent Advances in the Study of D-Histidine Methyl Ester Dihydrochloride (CAS: 5714-80-7)

D-Histidine Methyl Ester Dihydrochloride (CAS: 5714-80-7) is a derivative of the amino acid histidine, which has garnered significant attention in the field of chemical biology and pharmaceutical research due to its potential applications in drug development and biochemical studies. Recent studies have focused on its synthesis, characterization, and biological activities, shedding light on its utility as a building block for peptide synthesis and its role in modulating biological pathways.

One of the key advancements in the study of D-Histidine Methyl Ester Dihydrochloride is its improved synthetic methodology. Researchers have developed more efficient and scalable routes for its production, ensuring higher purity and yield. These advancements are critical for its application in large-scale pharmaceutical manufacturing. Additionally, the compound's stability under various physiological conditions has been investigated, providing insights into its potential as a drug candidate or a diagnostic tool.

In terms of biological activity, recent studies have explored the interaction of D-Histidine Methyl Ester Dihydrochloride with various enzymes and receptors. For instance, it has been shown to exhibit inhibitory effects on certain metalloproteinases, which are implicated in inflammatory diseases and cancer progression. These findings suggest its potential as a therapeutic agent for conditions characterized by excessive extracellular matrix degradation.

Furthermore, the compound's role in peptide synthesis has been a focal point of recent research. Its incorporation into peptide sequences has been demonstrated to enhance the stability and bioavailability of the resulting peptides, making it a valuable tool in the development of peptide-based therapeutics. This is particularly relevant in the context of targeted drug delivery systems, where peptide stability is paramount.

Another area of interest is the use of D-Histidine Methyl Ester Dihydrochloride in diagnostic applications. Its unique chemical properties make it suitable for use as a labeling agent in imaging studies, enabling researchers to track biological processes in real-time. This has potential implications for the early detection and monitoring of diseases such as cancer and neurodegenerative disorders.

In conclusion, the recent research on D-Histidine Methyl Ester Dihydrochloride (CAS: 5714-80-7) highlights its multifaceted applications in chemical biology and pharmaceutical sciences. From its role in peptide synthesis to its potential as a therapeutic and diagnostic agent, this compound continues to be a subject of intense investigation. Future studies are expected to further elucidate its mechanisms of action and expand its utility in medical and biochemical applications.

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