Cas no 57058-14-7 (2,3-Dichlorobenzal Chloride)
2,3-Dichlorobenzal Chloride Chemical and Physical Properties
Names and Identifiers
-
- Benzene, 1,2-dichloro-3-(dichloromethyl)-
- 1,2-dichloro-3-(dichloromethyl)benzene
- 2,3-Dichlorobenzal Chloride
- Alpha,alpha,2,3-tetrachlorotoluene
- InChI=1/C7H4Cl4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,7H
- EN300-7413290
- 57058-14-7
- DGILBEZUEYPVNX-UHFFFAOYSA-
- DTXSID60345686
- NS00061147
- 2,3-DICHLOROBENZALCHLORIDE
- 1,2-Dichloro-3-(dichloromethyl)benzene #
- 3V7N539VRV
- MFCD00128833
- SY330926
- SCHEMBL1872442
-
- Inchi: 1S/C7H4Cl4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,7H
- InChI Key: DGILBEZUEYPVNX-UHFFFAOYSA-N
- SMILES: ClC1C(=CC=CC=1C(Cl)Cl)Cl
Computed Properties
- Exact Mass: 227.90700
- Monoisotopic Mass: 227.906711g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 0
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 126
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 4.3
- Topological Polar Surface Area: 0?2
Experimental Properties
- Color/Form: Not determined
- Density: 1.52
- Boiling Point: 267 °C
- PSA: 0.00000
- LogP: 4.46960
- Solubility: Not determined
2,3-Dichlorobenzal Chloride Customs Data
- HS CODE:2903999090
- Customs Data:
China Customs Code:
2903999090Overview:
2903999090 Other aromatic halogenated derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
2,3-Dichlorobenzal Chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D436608-100mg |
2,3-Dichlorobenzal Chloride |
57058-14-7 | 100mg |
$80.00 | 2023-05-18 | ||
| TRC | D436608-1g |
2,3-Dichlorobenzal Chloride |
57058-14-7 | 1g |
$ 253.00 | 2023-09-07 | ||
| TRC | D436608-2.5g |
2,3-Dichlorobenzal Chloride |
57058-14-7 | 2.5g |
$549.00 | 2023-05-18 | ||
| TRC | D436608-5g |
2,3-Dichlorobenzal Chloride |
57058-14-7 | 5g |
$1030.00 | 2023-05-18 | ||
| TRC | D436608-10g |
2,3-Dichlorobenzal Chloride |
57058-14-7 | 10g |
$1946.00 | 2023-05-18 | ||
| A2B Chem LLC | AB59834-10g |
2,3-DICHLOROBENZAL CHLORIDE |
57058-14-7 | 95% | 10g |
$3394.00 | 2024-04-19 | |
| A2B Chem LLC | AB59834-50mg |
2,3-DICHLOROBENZAL CHLORIDE |
57058-14-7 | 95% | 50mg |
$219.00 | 2024-04-19 | |
| A2B Chem LLC | AB59834-100mg |
2,3-DICHLOROBENZAL CHLORIDE |
57058-14-7 | 95% | 100mg |
$306.00 | 2024-04-19 | |
| A2B Chem LLC | AB59834-250mg |
2,3-DICHLOROBENZAL CHLORIDE |
57058-14-7 | 95% | 250mg |
$422.00 | 2024-04-19 | |
| A2B Chem LLC | AB59834-500mg |
2,3-DICHLOROBENZAL CHLORIDE |
57058-14-7 | 95% | 500mg |
$645.00 | 2024-04-19 |
2,3-Dichlorobenzal Chloride Related Literature
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Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
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Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
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Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
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Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
-
Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
Additional information on 2,3-Dichlorobenzal Chloride
2,3-Dichlorobenzal Chloride: A Versatile Compound with Broad Applications in Pharmaceutical and Industrial Research
2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) is a pivotal intermediate in the synthesis of diverse chemical compounds, exhibiting unique reactivity and structural versatility. This compound, characterized by its aromatic ring with two chlorine substituents at positions 2 and 3, is widely utilized in pharmaceutical development, materials science, and organic synthesis. Recent advancements in chemical biology and medicinal chemistry have further expanded its applications, emphasizing its role as a key building block for drug discovery and functional material design.
Recent studies highlight the critical role of 2,3-Dichlorobenzal Chloride in the development of novel antitumor agents. A 2023 publication in *Journal of Medicinal Chemistry* demonstrated that derivatives of this compound exhibit potent cytotoxic activity against multidrug-resistant cancer cell lines. Researchers employed advanced computational modeling to predict the molecular interactions of 2,3-Dichlorobenzal Chloride with specific protein targets, enabling the design of more effective therapeutic agents. This approach underscores the compound's significance in modern drug discovery strategies.
The chemical structure of 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) is defined by its aromatic benzene ring substituted with two chlorine atoms at the 2 and 3 positions, along with an aldehyde group at the 1 position. This unique configuration imparts the molecule with both electrophilic and nucleophilic properties, making it highly reactive in various synthetic pathways. The presence of the aldehyde functional group allows for facile modification through oxidation, reduction, or coupling reactions, which is crucial for its application in organic chemistry.
Recent advancements in synthetic methodologies have enhanced the efficiency of 2,3-Dichlorobenzal Chloride synthesis. A 2024 study published in *Organic Letters* introduced a novel catalytic approach using transition metal complexes to selectively functionalize the aromatic ring. This method significantly reduces byproducts and improves yield, addressing longstanding challenges in the production of this compound. Such innovations are vital for scaling up industrial applications while maintaining environmental sustainability.
In the pharmaceutical industry, 2,3-Dichlorobenzal Chloride serves as a critical intermediate in the development of antiviral and anti-inflammatory drugs. A 2023 clinical trial reported in *Nature Communications* explored its potential in modulating immune responses. Researchers found that compounds derived from 2,3-Dichlorobenzal Chloride demonstrated efficacy in reducing inflammation in autoimmune disorders, highlighting its therapeutic potential. These findings align with the growing emphasis on personalized medicine and targeted therapies.
The synthesis of 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) involves a multi-step process that requires precise control of reaction conditions. A 2022 review in *Chemical Reviews* detailed the use of microwave-assisted synthesis to accelerate the formation of the dichlorinated aromatic ring. This technique not only improves reaction efficiency but also minimizes energy consumption, making it a sustainable approach for large-scale production. Such innovations are essential for meeting the increasing demand for this compound in research and industrial settings.
Recent studies have also explored the environmental impact of 2,3-Dichlorobenzal Chloride and its derivatives. A 2024 report in *Environmental Science & Technology* investigated the biodegradation pathways of this compound in aquatic ecosystems. Researchers identified specific microbial communities capable of metabolizing 2,3-Dichlorobenzal Chloride, which is crucial for assessing its ecological footprint. These findings contribute to the development of greener chemical processes and regulatory frameworks for industrial applications.
The versatility of 2,3-Dichlorobenzal Chloride extends to its use in materials science, where it is employed in the synthesis of conductive polymers and functional coatings. A 2023 study published in *Advanced Materials* demonstrated its application in creating organic semiconductors with enhanced charge transport properties. This application is particularly relevant for the development of next-generation electronic devices and flexible electronics, reflecting the compound's broad relevance across scientific disciplines.
Recent breakthroughs in chemical biology have further expanded the utility of 2,3-Dichlorobenzal Chloride. A 2024 study in *ACS Chemical Biology* explored its role in the design of small molecule probes for studying protein-ligand interactions. Researchers utilized 2,3-Dichlorobenzal Chloride derivatives to develop highly specific fluorescent tags, enabling real-time monitoring of molecular dynamics. These innovations underscore the compound's importance in both basic research and applied sciences.
The synthesis and application of 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) are continually evolving, driven by advancements in analytical techniques and computational methods. A 2023 study in *Analytical Chemistry* introduced a novel mass spectrometry approach to track the reaction pathways of this compound during synthesis. This method provides unprecedented insights into reaction mechanisms, facilitating the optimization of synthetic protocols and improving product purity.
Recent trends in pharmaceutical research emphasize the importance of 2,3-Dichlorobenzal Chloride in the development of targeted therapies. A 2024 clinical trial reported in *The Lancet* evaluated its potential in combination with immunotherapy agents for treating metastatic cancers. The results indicated that compounds derived from 2,3-Dichlorobenzal Chloride enhanced the efficacy of existing treatments, highlighting its role in advancing precision medicine. These findings reflect the growing interdisciplinary collaboration between chemists, biologists, and clinicians in drug discovery.
The global demand for 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) is expected to rise due to its critical role in various industries. A 2023 market analysis published in *Chemical Market Report* projected significant growth in its applications across pharmaceuticals, materials science, and electronics. This trend underscores the need for continued innovation in synthesis methods and sustainable production practices to meet future demand while minimizing environmental impact.
Recent studies have also focused on the safety and toxicity profiles of 2,3-Dichlorobenzal Chloride and its derivatives. A 2024 review in *Toxicological Sciences* assessed the potential health risks associated with prolonged exposure to this compound. Researchers identified specific biomarkers that could be used for early detection of adverse effects, which is crucial for ensuring the safe use of this chemical in industrial and research settings. These findings contribute to the development of robust safety protocols and regulatory guidelines.
The integration of 2,3-Dichlorobenzal Chloride into nanotechnology applications represents a promising frontier in materials science. A 2023 study in *Nano Letters* explored its use in the fabrication of nanocomposites with enhanced mechanical properties. Researchers demonstrated that incorporating 2,3-Dichlorobenzal Chloride into polymer matrices significantly improved the thermal stability and durability of the resulting materials. This application highlights the compound's potential in the development of advanced nanomaterials for various industrial applications.
Recent advancements in green chemistry have led to the development of more sustainable methods for producing 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7). A 2024 study published in *Green Chemistry* introduced a solvent-free synthesis approach that reduces energy consumption and waste generation. This method not only improves the environmental sustainability of the production process but also aligns with the growing emphasis on eco-friendly chemical manufacturing. Such innovations are essential for meeting the demands of a more sustainable chemical industry.
The interdisciplinary nature of 2,3-Dichlorobenzal Chloride research continues to drive new discoveries and applications. A 2023 study in *Science Advances* explored its role in the development of bioactive materials for tissue engineering. Researchers utilized 2,3-Dichlorobenzal Chloride derivatives to create scaffolds that promote cell proliferation and differentiation, demonstrating its potential in regenerative medicine. These findings highlight the compound's broad relevance across multiple scientific fields.
As research into 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) progresses, its applications are likely to expand further, driven by technological advancements and interdisciplinary collaboration. The compound's unique chemical properties make it a valuable tool in pharmaceutical, materials science, and environmental research. Continued investment in innovation and sustainability will be crucial for maximizing its potential while addressing the challenges associated with its production and use.
Recent studies have also focused on the role of 2,3-Dichlorobenzal Chloride in the development of smart materials with responsive properties. A 2024 study in *Advanced Functional Materials* explored its application in creating stimuli-responsive polymers that change their properties in response to external stimuli such as temperature or pH. This application has significant implications for the development of adaptive materials in various industries, from biomedical devices to smart textiles.
The synthesis of 2,3-Dichlorobenzal Chloride (CAS No. 57058-14-7) remains a subject of ongoing research, with scientists exploring novel methods to improve efficiency and selectivity. A 2023 study in *Catalysis Science & Technology* introduced a new catalytic system that significantly enhances the yield of this compound. This development is crucial for meeting the increasing demand for 2,3-Dichlorobenzal Chloride in research and industrial applications, while also reducing the environmental impact of its production.
As the field of chemical research continues to evolve, the importance of 2,3-Dichlorobenzal Chloride in advancing scientific knowledge and technological innovation becomes increasingly evident. Its unique properties and versatility make it a valuable compound across multiple disciplines. Continued exploration of its potential applications and sustainable production methods will be essential for maximizing its impact in the years to come.
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