Cas no 57-57-8 (b-Propiolactone)
b-Propiolactone Chemical and Physical Properties
Names and Identifiers
-
- Propiolactone
- 1,3-Propiolactone
- 2-Oxetanone
- 3-hydroxypropionic acid beta-lactone
- 3-hydroxypropionic acid lactone
- 3-Propiolactone
- beta3-Propiolactone
- BPL
- betaprone
- beta-propionolactone
- beta-Propiolactone
- Beta-PROPIOLACTONE (2-OXETANONE)
- beta-Propiolactone? Hydracrylic Acid beta Lactone
- oxetan-2-one
- Oxetanone
- Propionolactone
- Propanolide
- β-Propiolactone
- b-Propiolactone
- b-Propiolactone Solution
- β-Hydroxypropionic Acid Lactone
- β-Propionolactone
- Hydracrylicacid, b-lactone (6CI)
- 3-Propanolide
- NSC 21626
- Propanoic acid, 3-hydroxy-, b-lactone
- b-Propionolactone
- beta-Propiolakton
- Hydracrylic acid beta-lactone
- Propiolactonum
- Propiolactona
- .beta.-Propiolactone
- beta-Propanoic acid lactone
- beta-Proprolactone
- Caswell No. 709
- Propiolattone [DCIT]
- betapron
- beta-Propiolakton [Czech]
- Propiolactonum [INN-Latin]
- Propiolattone
- BP-31191
- WLN: T4OVTJ
- CHEBI:49073
- CCG-39865
- 2-oxetanona
- Propanoic acid, 3-hydroxy-, .beta.-lactone
- Spectrum2_001982
- NCGC00090802-03
- SBI-0051797.P002
- 2-Oxooxetane
- H0168
- Propiolactona [INN-Spanish]
- beta-lactone hydracrylic acid
- DTXSID8021197
- KBioGR_001888
- .beta.-Proprolactone
- Propiolactone, b-
- Hydracrylic acid ss-lactone
- Spectrum4_001274
- 3-propanolide; 1,3-propiolactone
- 6RC3ZT4HB0
- SPBio_002163
- KBio1_001003
- EINECS 200-340-1
- Tox21_111026
- CCRIS 536
- .beta.-lactone hydracrylic acid
- IDI1_001003
- NSC21626
- AKOS015906936
- beta-Propiolactone, Grade II, >=90%
- HMS1922K19
- Propiolactone .beta.-
- Propiolactone, .beta.-
- SPECTRUM1503234
- NCGC00090802-01
- 5-17-09-00003 (Beilstein Handbook Reference)
- Hydracrylic acid, .beta.-lactone
- EC 200-340-1
- Propionic acid, 3-hydroxy-, beta-lactone
- D0Z8AA
- PROPIOLACTONE [INN]
- FT-0622937
- SR-05000001970-1
- Hydracylic acid, .beta.lactone
- Hydracrylic Acid beta Lactone
- Propionic acid, .beta.-lactone
- KBio2_000696
- Hydracrylic acid .beta.-lactone
- .BETA.-PROPIOLACTONE [MI]
- BETA-PROPIOLACTONE [IARC]
- NINDS_001003
- beta-Propriolactone; see 1910.1013
- KBio2_005832
- NCGC00090802-02
- .beta.-Propiolakton
- MFCD00005169
- PROPIOLACTONE [HSDB]
- LS-230
- .beta.-Propriolactone
- oxetan-2one
- AT19319
- 3-Propiolacetone
- Propiolactone [USAN:INN:BAN]
- HSDB 811
- NSC758422
- EPA Pesticide Chemical Code 010901
- 57-57-8
- Propanoic acid, .beta.-lactone
- SR-05000001970
- 2-Oxacyclobutanone
- Pharmakon1600-01503234
- 3-Hydroxy-beta-lactone
- Propionic acid, 3-hydroxy-, .beta.-lactone
- PLT (CHRIS Code)
- PROPIOLACTONE [MART.]
- PROPIOLACTONE [ORANGE BOOK]
- beta-Hydroxypropionic Acid Lactone
- Q420715
- 25037-58-5
- Z1089877620
- KBioSS_000696
- UNII-6RC3ZT4HB0
- Betaprone (TN)
- 3-Hydroxypropionic acid, lactone
- Spectrum_000216
- NSC-21626
- HMS503I07
- NSC-758422
- CAS-57-57-8
- BCP07366
- Beta-PROPIOLACTONE (2 -OXETANONE)
- Propiolactone, beta-
- DTXCID801197
- DB09348
- .beta.-Propanoic acid lactone
- .beta.-Propionolactone
- AM20020040
- EN300-68177
- KBio2_003264
- A936942
- D05630
- CHEMBL1200627
- InChI=1/C3H4O2/c4-3-1-2-5-3/h1-2H
- Propiolactone (USAN/INN)
- Propanoic acid, 3-hydroxy-, beta-lactone
- BRN 0001360
- HMS2092P12
- DivK1c_001003
- AB00052333_02
- hydroacrylic acid
- C19297
- AI3-24257
- Propiolactone [USAN:BAN:INN]
- PROPIOLACTONE [USAN]
- 3-Hydroxypropionic acid .beta.-lactone
- Propiolactonum (INN-Latin)
- Hydracrylic Acid, b-Lactone
- beta Propiolactone
- HYDRACRYLIC ACID, BETA-LACTONE
- BETRAPRONE
- PROPANOIC ACID, 3-HYDROXY-,BETA-LACTONE
- HYDROACRYLIC ACID, BETA-LACTONE
- HYDRACRYLIC ACID, BETA LACTONE
- NS00005909
- PROPIOLACTONE (MART.)
- HY-107931
- Propanilide
- 3-Hydroxypropionic Acid, b-Lactone
- Propiolactona (INN-Spanish)
- CS-0030919
- 3-HYDROXYPROPIONIC ACID, BETA-LACTONE
- BETA-PROPIOLACTONE (IARC)
- beta-PL
- PROPIONIC ACID 3-HYDROXY-BETA-LACTONE
- PROPIONIC ACID, 3-HYDROXY-,BETA-LACTONE
- HYDRACRYLIC ACID,BETA,LACTONE
- DB-003748
- ? PROPIOLACTONE
- BRD-K76867903-001-03-8
-
- MDL： MFCD00005169
- Inchi： 1S/C3H4O2/c4-3-1-2-5-3/h1-2H2
- InChI Key： VEZXCJBBBCKRPI-UHFFFAOYSA-N
- SMILES： O1C(CC1)=O
Computed Properties
- Exact Mass: 72.02110
- Monoisotopic Mass: 72.021
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 5
- Rotatable Bond Count: 0
- Complexity: 57.9
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 2
- XLogP3: -0.2
- Topological Polar Surface Area: 26.3
Experimental Properties
- Color/Form: Colorless toxic liquid with flammability.
- Density: 1.146
- Melting Point: -33 oC
- Boiling Point: 165°C(lit.)
- Flash Point: 70 oC
- Refractive Index: 1.412-1.414
- Water Partition Coefficient: 37 g/100 mL
- PSA: 26.30000
- LogP: -0.06670
- Solubility: Soluble in most organic solvents, it is often used in CH2Cl2, THF and DMF.
- Merck: 7820
- Sensitiveness: Moisture Sensitive
b-Propiolactone Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H315,H319,H330,H350
- Warning Statement： P201,P260,P284,P305+P351+P338,P310
- Hazardous Material transportation number：UN 3382 6.1/PG 1
- WGK Germany：3
- Hazard Category Code： R26;R36/38;R45
- Safety Instruction： S53-S45
- RTECS：RQ7350000
-
Hazardous Material Identification：
- Packing Group：I
- Hazard Level：6.1
- HazardClass：6.1
- PackingGroup：I
- TSCA：Yes
- Storage Condition：<0°C
- Safety Term：6.1
- Packing Group：I
- Risk Phrases：R26; R36/38; R45
b-Propiolactone Customs Data
- HS CODE：2932209090
- Customs Data：
China Customs Code:
2932209090Overview:
2932209090. Other lactones. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
b-Propiolactone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | H0168-25G |
β-Propiolactone |
57-57-8 | >95.0%(GC)(T) | 25g |
￥3090.00 | 2024-04-16 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BP7736-1ml |
b-Propiolactone |
57-57-8 | ≥98% | 1ml |
￥390元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BP7736-5ml |
b-Propiolactone |
57-57-8 | ≥98% | 5ml |
￥1480元 | 2023-09-15 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R018534-5ml |
b-Propiolactone |
57-57-8 | 95% | 5ml |
￥744 | 2024-05-22 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R018534-1ml |
b-Propiolactone |
57-57-8 | 95% | 1ml |
￥209 | 2024-05-22 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | H0168-5G |
β-Propiolactone |
57-57-8 | >95.0%(GC)(T) | 5g |
￥1055.00 | 2024-04-16 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | P816096-25ml |
β-Propiolactone |
57-57-8 | >95.0%(GC) | 25ml |
3,520.00 | 2021-05-17 | |
| BAI LING WEI Technology Co., Ltd. | 57-57-8-5ml |
beta-Propiolactone |
57-57-8 | 98.50% | 5ml |
￥ 827 | 2022-04-26 | |
| BAI LING WEI Technology Co., Ltd. | 996513-5ML |
β-Propiolactone, 98%, research grade |
57-57-8 | 98% | 5ML |
￥ 752 | 2022-04-26 | |
| BAI LING WEI Technology Co., Ltd. | 57-57-8-25ml |
beta-Propiolactone |
57-57-8 | 98.50% | 25ml |
￥ 2475 | 2022-04-26 |
b-Propiolactone Suppliers
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b-Propiolactone Related Literature
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1. Thermal unimolecular decomposition of β-propiolactone (oxetan-2-one)H. Monty Frey,Ivy M. Pidgeon J. Chem. Soc. Faraday Trans. 1 1985 81 1087
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Aisa Hosseinnejad,Nadine Ludwig,Ann-Katrin Wienkamp,Rahul Rimal,Christian Bleilevens,Rolf Rossaint,Jan Rossaint,Smriti Singh Biomater. Sci. 2022 10 85
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Greta Becker,Frederik R. Wurm Chem. Soc. Rev. 2018 47 7739
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4. Strain effects in acyl transfer reactions. Part 4. Kinetic analysis of the reaction of imidazole buffer solutions with β-propiolactone using a novel graphical method for branched, series reactionsG. Michael Blackburn,David Duce J. Chem. Soc. Perkin Trans. 2 1977 1492
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Xiaobing Zhang,Youai Qiu,Chunling Fu,Shengming Ma Org. Chem. Front. 2014 1 247
Additional information on b-Propiolactone
B-Propiolactone (CAS No. 57-57-8): Properties, Applications, and Industry Insights
B-Propiolactone (CAS No. 57-57-8), also known as beta-propiolactone or 2-oxetanone, is a versatile organic compound with a wide range of industrial and research applications. This four-membered lactone ring structure is characterized by its high reactivity, making it a valuable intermediate in chemical synthesis. The compound's molecular formula, C3H4O2, and unique properties have garnered significant attention in recent years, particularly in pharmaceutical manufacturing and material science.
The growing interest in b-propiolactone uses reflects its importance in modern chemistry. Researchers frequently search for b-propiolactone synthesis methods and b-propiolactone safety data, indicating its relevance across multiple disciplines. Its ability to act as an alkylating agent makes it particularly useful in the production of specialty chemicals, where precise molecular modifications are required. Recent advancements in green chemistry have also explored b-propiolactone derivatives as potential sustainable alternatives in various applications.
One of the most searched topics regarding 57-57-8 compound involves its role in pharmaceutical intermediates. The compound's reactivity allows for efficient modification of biological molecules, making it valuable in drug development. Current research focuses on b-propiolactone in vaccine production, where its properties contribute to inactivation processes while maintaining immunogenicity. This application has become particularly relevant in light of recent global health developments, though the compound's utility extends far beyond this single use case.
From a materials science perspective, beta-propiolactone applications include polymer synthesis and surface modification. The compound's ability to form poly(propiolactone) has attracted attention in biodegradable polymer research, aligning with current sustainability trends. Industry professionals often search for b-propiolactone technical specifications and b-propiolactone storage requirements, reflecting the need for precise handling information in industrial settings.
The analytical characterization of CAS 57-57-8 involves various spectroscopic techniques, with many researchers seeking information about b-propiolactone NMR spectra and b-propiolactone IR peaks. These analytical methods are crucial for quality control in manufacturing processes and for verifying the compound's purity in research applications. Recent publications have highlighted novel detection methods for 2-oxetanone derivatives in complex mixtures, demonstrating ongoing innovation in this field.
Environmental considerations surrounding b-propiolactone degradation have become increasingly important. The scientific community shows growing interest in b-propiolactone environmental fate studies, particularly regarding its breakdown products and persistence. This aligns with broader industry trends toward eco-conscious chemical usage and waste management. Current research explores microbial degradation pathways and advanced oxidation processes for beta-propiolactone removal from industrial effluents.
In the realm of biochemical applications, 57-57-8 chemical has shown promise in protein modification studies. Researchers investigating b-propiolactone protein crosslinking often utilize its bifunctional reactivity. This property has applications in enzyme stabilization and biomaterial development, areas that have gained prominence in biotechnology and medical research. The compound's specific interactions with amino acid residues continue to be an active area of investigation.
The commercial availability of b-propiolactone meets diverse industry needs, with suppliers frequently queried about b-propiolactone purity grades and b-propiolactone packaging options. The global market for this chemical reflects its widespread utility, with quality standards varying based on intended applications. Recent supply chain analyses indicate stable production capacity for CAS 57-57-8, ensuring reliable access for industrial and research users worldwide.
Future perspectives on beta-propiolactone technology suggest expanding applications in nanotechnology and advanced materials. The compound's molecular structure offers unique opportunities for creating functionalized surfaces and nanostructures. Emerging research explores b-propiolactone copolymerization techniques for developing novel materials with tailored properties, potentially opening new markets for this versatile chemical intermediate.
Quality control protocols for b-propiolactone remain a critical concern, with analytical chemists frequently referencing b-propiolactone HPLC methods and b-propiolactone stability studies. These methodologies ensure product consistency across batches and applications. Recent advancements in analytical instrumentation have improved detection limits and selectivity for 2-oxetanone analysis, benefiting both manufacturers and end-users.
The regulatory landscape surrounding CAS 57-57-8 continues to evolve, with professionals regularly consulting b-propiolactone handling guidelines and b-propiolactone regulatory status updates. These considerations are essential for compliant use across different jurisdictions and industries. Current best practices emphasize proper engineering controls and personal protective equipment when working with this reactive compound.
Academic interest in b-propiolactone chemistry persists, with numerous studies investigating its reaction mechanisms and potential novel applications. The compound's versatility ensures its continued relevance in organic synthesis methodologies. Recent literature highlights innovative uses of beta-propiolactone derivatives in asymmetric synthesis and catalyst development, demonstrating the ongoing potential for discovery in this field.
Industrial scale production of b-propiolactone has adapted to meet changing market demands, with process engineers optimizing b-propiolactone manufacturing processes for efficiency and sustainability. Modern production facilities incorporate advanced monitoring systems to ensure consistent quality of CAS 57-57-8 products. These improvements reflect the chemical industry's broader commitment to responsible production practices.
In conclusion, b-propiolactone (CAS No. 57-57-8) remains a compound of significant scientific and industrial importance. Its diverse applications span multiple sectors, from pharmaceuticals to advanced materials, with ongoing research continuing to uncover new potential uses. The compound's unique chemical properties ensure its continued relevance in an evolving technological landscape, while proper handling and application knowledge remain essential for its effective and responsible utilization across all fields.
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