Cas no 5685-36-9 (2-Phenylcyclopropanecarbonyl chloride)
2-Phenylcyclopropanecarbonyl chloride Chemical and Physical Properties
Names and Identifiers
-
- Cyclopropanecarbonyl chloride, 2-phenyl-
- 2-phenylcyclopropane-1-carbonyl chloride
- 2-phenylcyclopropanecarbonyl chloride
- SCHEMBL452299
- SODZBMGDYKEZJG-UHFFFAOYSA-N
- DTXSID90335151
- STR07393
- MFCD00066868
- FT-0741108
- Cyclopropanecarbonyl chloride, 2-phenyl-, trans-
- NS00041922
- 2-phenyl-1-cyclopropanecarboxylic acid chloride
- AKOS030239448
- 2-phenyl-1-cyclopropanecarbonyl chloride
- FT-0633162
- 5685-36-9
- EN300-318573
- DA-04797
- 37107-48-5
- 2-Phenylcyclopropanecarbonyl chloride
-
- MDL: MFCD00066868
- Inchi: 1S/C10H9ClO/c11-10(12)9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6H2
- InChI Key: SODZBMGDYKEZJG-UHFFFAOYSA-N
- SMILES: ClC(C1CC1C1C=CC=CC=1)=O
Computed Properties
- Exact Mass: 180.03427
- Monoisotopic Mass: 180.0341926g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 184
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 2
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.6
- Topological Polar Surface Area: 17.1?2
Experimental Properties
- Color/Form: NA
- Density: 1.3±0.1 g/cm3
- Boiling Point: 278.0±0.0 °C at 760 mmHg
- Flash Point: 175.6±28.4 °C
- PSA: 17.07
2-Phenylcyclopropanecarbonyl chloride Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:Storage at -4 ℃ (6-12weeks), long storage period at -20 ℃ (1-2years), transport at 0 ℃
2-Phenylcyclopropanecarbonyl chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 114591-1g |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 97% | 1g |
9346.0CNY | 2021-07-13 | |
| TRC | P400305-10mg |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 10mg |
$ 50.00 | 2022-06-03 | ||
| TRC | P400305-50mg |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 50mg |
$ 210.00 | 2022-06-03 | ||
| TRC | P400305-100mg |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 100mg |
$ 320.00 | 2022-06-03 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 114591-1g |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 97% | 1g |
9346CNY | 2021-05-07 | |
| abcr | AB540609-1 g |
2-Phenylcyclopropanecarbonyl chloride; . |
5685-36-9 | 1g |
€130.90 | 2023-04-14 | ||
| A2B Chem LLC | AW34092-500mg |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 97% | 500mg |
$490.00 | 2024-04-19 | |
| A2B Chem LLC | AW34092-1g |
2-Phenylcyclopropanecarbonyl chloride |
5685-36-9 | 97% | 1g |
$727.00 | 2024-04-19 | |
| abcr | AB540609-2.52,5g |
2-Phenylcyclopropanecarbonyl chloride; . |
5685-36-9 | 2.52,5g |
€182.50 | 2024-04-17 | ||
| Enamine | EN300-318573-1g |
2-phenylcyclopropane-1-carbonyl chloride |
5685-36-9 | 1g |
$628.0 | 2023-09-05 |
2-Phenylcyclopropanecarbonyl chloride Suppliers
2-Phenylcyclopropanecarbonyl chloride Related Literature
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Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
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Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
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Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
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Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
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Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
Additional information on 2-Phenylcyclopropanecarbonyl chloride
Comprehensive Guide to 2-Phenylcyclopropanecarbonyl chloride (CAS No. 5685-36-9): Properties, Applications, and Industry Insights
2-Phenylcyclopropanecarbonyl chloride (CAS No. 5685-36-9) is a specialized organic compound widely recognized for its unique cyclopropane ring structure and carbonyl chloride functional group. This compound has garnered significant attention in pharmaceutical and agrochemical research due to its versatile reactivity. With the growing demand for fine chemicals and building blocks in synthetic chemistry, understanding its properties and applications is critical for researchers and industry professionals.
The molecular formula of 2-Phenylcyclopropanecarbonyl chloride is C10H9ClO, and it features a phenyl group attached to a strained three-membered cyclopropane ring. This structural configuration contributes to its high reactivity, making it valuable for amide bond formation and peptide coupling reactions. Recent studies highlight its role in developing bioactive molecules, particularly in drug discovery and material science.
In the context of green chemistry, researchers are exploring sustainable synthesis routes for 2-Phenylcyclopropanecarbonyl chloride to minimize environmental impact. Questions like "How is 2-Phenylcyclopropanecarbonyl chloride synthesized?" or "What are the alternatives to traditional acyl chlorides?" are frequently searched in academic databases and AI-driven platforms, reflecting the compound's relevance in modern chemistry.
From an industrial perspective, 2-Phenylcyclopropanecarbonyl chloride is utilized in the production of advanced intermediates for pharmaceuticals and specialty chemicals. Its application in asymmetric synthesis and catalysis has been a focal point for innovation. Companies are increasingly investing in high-purity grades of this compound to meet the stringent requirements of GMP manufacturing.
Safety and handling of 2-Phenylcyclopropanecarbonyl chloride are also critical topics. While it is not classified under restricted categories, proper storage conditions—such as anhydrous environments and temperature control—are essential to maintain stability. Searches like "Is 2-Phenylcyclopropanecarbonyl chloride moisture-sensitive?" underscore user concerns about its practical usage.
Looking ahead, the demand for 2-Phenylcyclopropanecarbonyl chloride is expected to rise, driven by advancements in medicinal chemistry and crop protection formulations. Its compatibility with flow chemistry and continuous processing further positions it as a key player in the future of industrial-scale synthesis.
In summary, 2-Phenylcyclopropanecarbonyl chloride (CAS No. 5685-36-9) represents a pivotal chemical intermediate with broad applications. By addressing common queries and aligning with trends like sustainable synthesis and AI-assisted research, this guide aims to provide a holistic view of its significance in contemporary science.
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