• 1. Evolving better nanoparticles: Genetic algorithms for optimising cluster geometries
  Dalton Trans., 2003, 4193-4207
• 2. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 3. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 4. Excellent humidity sensor based on ultrathin HKUST-1 nanosheets?
  Qiaoe Wang,Meiling Lian,Xiaowen Zhu,Xu Chen RSC Adv., 2021,11, 192-197
• 5. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Methoxybenzoic acids and derivatives

Research Briefing on BENZOIC ACID, 4-AMINO-3,5-DIMETHOXY-, METHYL ESTER (CAS: 56066-25-2)

BENZOIC ACID, 4-AMINO-3,5-DIMETHOXY-, METHYL ESTER (CAS: 56066-25-2) is a chemical compound of significant interest in the field of chemical biology and pharmaceutical research. This ester derivative, characterized by its amino and dimethoxy functional groups, has been investigated for its potential applications in drug development, particularly as an intermediate in the synthesis of bioactive molecules. Recent studies have explored its role in modulating biological pathways, its pharmacokinetic properties, and its utility in medicinal chemistry.

One of the key areas of research involving this compound is its application in the synthesis of novel therapeutic agents. A 2023 study published in the Journal of Medicinal Chemistry highlighted its use as a precursor in the development of kinase inhibitors, which are crucial for targeting cancer-related signaling pathways. The study demonstrated that the compound's structural features, including the methoxy and amino groups, contribute to its binding affinity and selectivity toward specific kinase targets.

Another recent investigation, featured in Bioorganic & Medicinal Chemistry Letters, focused on the compound's potential as a building block for antimicrobial agents. Researchers synthesized a series of derivatives based on BENZOIC ACID, 4-AMINO-3,5-DIMETHOXY-, METHYL ESTER and evaluated their efficacy against drug-resistant bacterial strains. The results indicated that certain derivatives exhibited promising antibacterial activity, suggesting its utility in addressing the growing challenge of antimicrobial resistance.

In addition to its pharmacological applications, the compound has also been studied for its chemical properties. A 2022 paper in the Journal of Organic Chemistry detailed its reactivity in various synthetic transformations, emphasizing its versatility as a synthetic intermediate. The study provided insights into optimizing reaction conditions to enhance yield and purity, which are critical for large-scale pharmaceutical production.

Despite these advancements, challenges remain in fully harnessing the potential of BENZOIC ACID, 4-AMINO-3,5-DIMETHOXY-, METHYL ESTER. Issues such as solubility, stability, and metabolic clearance need to be addressed to improve its drug-like properties. Ongoing research aims to overcome these limitations through structural modifications and formulation strategies.

In conclusion, BENZOIC ACID, 4-AMINO-3,5-DIMETHOXY-, METHYL ESTER (CAS: 56066-25-2) represents a valuable compound in chemical biology and pharmaceutical research. Its diverse applications, from kinase inhibitors to antimicrobial agents, underscore its importance in drug discovery. Future studies will likely focus on optimizing its properties and expanding its therapeutic potential, making it a compound to watch in the coming years.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)