Cas no 56038-13-2 (Sucralose)

Sucralose is a non-nutritive sweetener derived from sucrose, characterized by its high sweetness intensity and low caloric content. It exhibits excellent stability in heat, acidity, and alkalinity, making it suitable for use in various food products, beverages, and pharmaceutical applications where reduced sugar intake is beneficial.
Sucralose structure
Sucralose structure
Product Name:Sucralose
CAS No:56038-13-2
MF:C12H19Cl3O8
MW:397.633462190628
MDL:MFCD03648615
CID:56887
PubChem ID:135726973
Update Time:2025-07-28

Sucralose Chemical and Physical Properties

Names and Identifiers

    • Sucralose
    • (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
    • (2R,3R,4R,5R,6R)-2-{[(2S,3R,4R,5R)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydro furan-2-yl]oxy}-5-chloro-6-(hydroxymet...
    • (2R,3R,4R,5R,6R)-2-{[(2S,3R,4R,5R)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydro furan-2-yl]oxy}-5-chloro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
    • SUCRALOSE(P)
    • 1',4,6'-Trichlorogalactosucrose
    • 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactose
    • 1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl4-chloro-4-deoxy-alpha-d-gala
    • 1,6-DICHLORO-1,6-DIDEOXY-BETA-D-FRUCTOFURANOSYL-4-CHLORO-4-DEOXY-ALPHA-D-GALACOTOPYRANOSIDE
    • E955
    • EINECS 259-952-2
    • Splenda
    • UNII-96K6UQ3ZD4
    • 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside
    • Trichlorosucrose
    • 1-(1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl)-4-chloro-4-deoxy-α-D-galactopyranoside
    • 湖北三氯蔗糖生產(chǎn)廠家
    • Aspasvit
    • Acucar Light
    • Trichlorogalacto-sucrose
    • 96K6UQ3ZD4
    • 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactopyranoside
    • Trichlorogalactosucrose
    • 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside
    • Sucralose [BAN]
    • 4,1',6'-Trichloro-4,1',6'-trideoxy-galacto-sucrose
    • DSSTox_CID_20245
    • DSSTox_RID_7
    • Sucralose Standard
    • Sucralose,98%
    • Pharmakon1600-01505953
    • NSC759272
    • NCGC00249110-03
    • 1',6'-dichloro-1',6-dideoxy-beta-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside
    • (2R,3R,4R,5R,6R)-2-((2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxytetrahydrofuran-2-yloxy)-5-chloro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
    • BRD-K58968598-001-02-8
    • CHEBI:32159
    • SUCRALOSE (USP-RS)
    • SUCRALOSE (II)
    • 1,6-dichloro-1,6-dideoxy-.beta.-d-fructofuranosyl-4-chloro-4-deoxy-.alpha.-d-galactopyranoside
    • BRD-K58968598-001-03-6
    • 1',4',6'-TRICHLORO-GALACTOSUCROSE
    • a-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl4-chloro-4-deoxy-
    • NCGC00249110-01
    • Q410209
    • Sucralose; 1,6-Dichloro-1,6-dideoxy-beta-d-fructofuranosyl 4-chloro-4-deoxy-alpha-d-galactopyranoside
    • Tox21_201752
    • E-955
    • Tox21_303425
    • BDBM50367128
    • Sucralose, >=98.0% (HPLC)
    • 56038-13-2
    • CS-8130
    • MFCD03648615
    • SUCRALOSE [MI]
    • SUCRALOSE [MART.]
    • E955;Trichlorosucrose
    • INS NO.955
    • Sucralose [BAN:NF]
    • 1-(1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl)-4-chloro-4-deoxy-alpha-D-galactopyranoside
    • SR-05000001935-1
    • SUCRALOSE [II]
    • AKOS015962432
    • CCRIS 8449
    • HY-N0614
    • (2R,3R,4R,5R,6R)-2-(((2R,3S,4S,5S)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydrofuran-2-yl)oxy)-5-chloro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
    • Sansweet su 100
    • SUCRALOSE [FCC]
    • DTXCID9020245
    • SUCRALOSE [WHO-DD]
    • AB01563242_02
    • SUCRALOSE (EP MONOGRAPH)
    • NCGC00249110-04
    • 1',4',6'-Trideoxy-trichloro-galactosucrose
    • SBI-0206860.P001
    • alpha-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-
    • 4,1',6'-trichlorogalactosucrose
    • NSC-759272
    • CAS-56038-13-2
    • BAQAVOSOZGMPRM-QBMZZYIRSA-N
    • 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl-4-chloro-4-deoxy-a-D-galactopyranoside
    • Sucrazit
    • Sucralose, European Pharmacopoeia (EP) Reference Standard
    • Sucralose, Pharmaceutical Secondary Standard; Certified Reference Material
    • DTXSID1040245
    • Tox21_113658
    • AB01563242_01
    • BRN 3654410
    • Sucralose, analytical standard
    • NSC 759272
    • SCHEMBL3686
    • Sucralose, United States Pharmacopeia (USP) Reference Standard
    • NCGC00257400-01
    • CCG-213995
    • W-203112
    • (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]oxy-5-chloro-6-(hydroxymethyl)tetrahydropyran-3,4-diol
    • NS00000320
    • SUCRALOSE [USP-RS]
    • INS-955
    • SUCRALOSE [EP MONOGRAPH]
    • San sweet sa 8020
    • NCGC00259301-01
    • SR-05000001935
    • Sucralose 1000 microg/mL in Acetonitrile
    • .alpha.-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-.beta.-D-fructofuranosyl 4-chloro-4-deoxy-
    • CHEMBL3185084
    • HMS2093H16
    • s4214
    • SUCRALOSE (MART.)
    • HSDB 7964
    • 1,6-Dichloro-1,6-dideoxy-b-D-fructofuranosyl-4-chloro-4-deoxy-a-D-galactopyranoside
    • 259-952-2
    • OS04165
    • MDL: MFCD03648615
    • Inchi: 1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
    • InChI Key: BAQAVOSOZGMPRM-QBMZZYIRSA-N
    • SMILES: Cl[C@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@@]1(CCl)[C@H]([C@@H]([C@@H](CCl)O1)O)O
    • BRN: 3654410

Computed Properties

  • Exact Mass: 396.01500
  • Monoisotopic Mass: 396.014551
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 5
  • Hydrogen Bond Acceptor Count: 8
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 5
  • Complexity: 405
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 9
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: -1.5
  • Topological Polar Surface Area: 129

Experimental Properties

  • Color/Form: Powder
  • Density: 1.375 g/cm
  • Melting Point: 130°C(lit.)
  • Boiling Point: 669.4°C at 760 mmHg
  • Flash Point: 358.7±31.5 °C
  • Refractive Index: 1.604
  • Solubility: Do you have solubility information on this product that you would like to share
  • Water Partition Coefficient: Soluble in Water.
  • PSA: 128.84000
  • LogP: -1.65610
  • Merck: 8880
  • Specific Rotation: +84.0 ~ +88.0° (c=1, H2O)
  • Optical Activity: [α]/D 86.0±2.0°, c =?1 in H2O
  • Solubility: It is very soluble in water, ethanol and methanol, and slightly soluble in diethyl ether.
  • Vapor Pressure: 3.25X10-14 mm Hg at 25 °C (est)

Sucralose Security Information

Sucralose Customs Data

  • HS CODE:2932999099
  • Customs Data:

    China Customs Code:

    2932999099

    Overview:

    2932999099. Other heterocyclic compounds containing only oxygen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Sucralose Pricemore >>

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Sucralose Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:56038-13-2)Sucralose
Order Number:sfd21153
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:56038-13-2)Sucralose Standard
Order Number:A22902
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:14
Price ($):175.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:56038-13-2)Sucralose
Order Number:LE9858;LE3297160;LE565
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:02
Price ($):discuss personally

Sucralose Spectrogram

1H NMR 300 MHz DMSO
1H NMR
LC-MS
LC-MS
13C NMR
13C NMR

Additional information on Sucralose

The Comprehensive Guide to Sucralose (CAS No. 56038-13-2): Properties, Applications, and Market Trends

Sucralose (CAS No. 56038-13-2) is one of the most widely used artificial sweeteners in the world. Known for its high-intensity sweetness and zero-calorie properties, it is approximately 600 times sweeter than sucrose (table sugar). This makes it a popular choice for sugar-free products, diet beverages, and low-calorie foods. Its chemical stability under high temperatures also allows it to be used in baking and cooking applications, unlike some other sweeteners.

The molecular structure of Sucralose is derived from sucrose through a selective chlorination process, replacing three hydroxyl groups with chlorine atoms. This modification enhances its sweetness while making it non-caloric and non-cariogenic (does not promote tooth decay). Due to its low glycemic index, it is often recommended for people managing diabetes or those following keto diets.

In recent years, the demand for Sucralose has surged due to increasing health consciousness and the global rise in obesity and diabetes. Consumers are actively searching for "best sugar substitutes", "safe artificial sweeteners", and "Sucralose vs. Stevia" comparisons. Studies have confirmed its safety for human consumption, with regulatory approvals from the FDA, EFSA, and WHO.

Beyond food and beverages, Sucralose is used in pharmaceutical formulations to improve the taste of medicines, particularly in pediatric and geriatric products. It is also found in oral care products like sugar-free chewing gum and toothpaste, thanks to its ability to prevent dental cavities.

The global Sucralose market is projected to grow significantly, driven by trends in clean-label products and sugar reduction initiatives. Manufacturers are innovating with Sucralose blends to improve taste profiles, addressing common consumer complaints about aftertaste in artificial sweeteners. Additionally, the shift toward plant-based and vegan diets has further boosted its adoption.

Environmental concerns related to Sucralose production have also gained attention, with researchers exploring sustainable synthesis methods. Unlike some sweeteners, Sucralose is not metabolized by the body, leading to questions about its environmental impact in wastewater. However, advancements in green chemistry are addressing these challenges.

For consumers wondering "Is Sucralose bad for you?", extensive research supports its safety when consumed within acceptable daily intake (ADI) levels. However, debates continue regarding long-term effects of artificial sweeteners, prompting ongoing studies. Meanwhile, Sucralose remains a key player in the food additive industry, offering a balance between sweetness and health considerations.

In summary, Sucralose (CAS No. 56038-13-2) is a versatile, scientifically backed sweetener with expanding applications in food, pharmaceuticals, and oral care. Its role in weight management and diabetes-friendly diets ensures its relevance in today’s health-focused market. As consumer preferences evolve, Sucralose innovations will continue to shape the future of sugar alternatives.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:56038-13-2)Sucralose
sfd21153
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Amadis Chemical Company Limited
(CAS:56038-13-2)Sucralose Standard
A22902
Purity:99%
Quantity:100g
Price ($):175.0
Email