• 1. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 2. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 3. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 4. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 5. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylpropanes

Professional Introduction to 1-(4-(Benzyloxy)phenyl)propan-2-one (CAS No. 5586-92-5)

1-(4-(Benzyloxy)phenyl)propan-2-one, identified by its Chemical Abstracts Service (CAS) number 5586-92-5, is a significant compound in the field of pharmaceutical chemistry and organic synthesis. This molecule, featuring a benzyloxy-substituted phenyl ring connected to a propan-2-one backbone, has garnered attention due to its structural versatility and potential applications in drug development and material science. The unique arrangement of functional groups in this compound makes it a valuable intermediate for synthesizing more complex molecules, particularly in the design of bioactive agents.

The structural framework of 1-(4-(Benzyloxy)phenyl)propan-2-one combines the aromatic stability of the phenyl ring with the reactivity of the benzyloxy and ketone functionalities. This combination allows for diverse chemical modifications, making it a versatile building block in synthetic chemistry. The benzyloxy group, in particular, is known for its ability to enhance solubility and metabolic stability, which are critical factors in pharmaceutical design. The propan-2-one moiety provides a site for further functionalization, enabling the creation of more intricate molecular structures.

In recent years, research into 1-(4-(Benzyloxy)phenyl)propan-2-one has focused on its role as a precursor in the synthesis of pharmacologically active compounds. Studies have demonstrated its utility in the preparation of derivatives with potential applications in treating neurological disorders, inflammatory conditions, and even oncological diseases. The phenyl ring and its substituents can interact with biological targets in specific ways, influencing receptor binding and signal transduction pathways. This has led to investigations into its derivatives as potential leads for novel therapeutic agents.

The synthesis of 1-(4-(Benzyloxy)phenyl)propan-2-one typically involves multi-step organic reactions, often starting from readily available aromatic precursors. Advanced synthetic methodologies, such as palladium-catalyzed cross-coupling reactions and transition-metal-mediated transformations, have been employed to achieve high yields and purity. These techniques are essential for ensuring that the final product meets the stringent requirements of pharmaceutical applications. The ability to produce this compound efficiently is crucial for both academic research and industrial-scale manufacturing.

One of the most compelling aspects of 1-(4-(Benzyloxy)phenyl)propan-2-one is its potential in medicinal chemistry. Researchers have explored its derivatives as inhibitors of enzymes involved in disease pathways. For instance, modifications to the benzyloxy group have been investigated for their effects on enzyme selectivity and potency. Such studies highlight the importance of this compound as a scaffold for developing new drugs that can target specific biological processes with high precision.

The chemical properties of 1-(4-(Benzyloxy)phenyl)propan-2-one, including its solubility profile and thermal stability, also make it an attractive candidate for material science applications. Its ability to undergo further functionalization allows for the creation of polymers and coatings with tailored properties. These materials could find use in various industries, from electronics to biomedicine, where precise control over molecular structure is essential.

The growing interest in green chemistry has also influenced research on 1-(4-(Benzyloxy)phenyl)propan-2-one. Efforts are being made to develop synthetic routes that minimize waste and reduce environmental impact. Catalytic processes and solvent-free reactions are being explored as alternatives to traditional methods. These advancements not only improve the sustainability of producing this compound but also enhance its overall appeal as a chemical building block.

In conclusion, 1-(4-(Benzyloxy)phenyl)propan-2-one (CAS No. 5586-92-5) represents a fascinating intersection of pharmaceutical chemistry and organic synthesis. Its structural features and reactivity make it a valuable intermediate for developing new drugs and advanced materials. As research continues to uncover new applications for this compound, its significance in both academic and industrial settings is likely to grow further. The ongoing development of efficient synthetic methods ensures that access to this versatile molecule will remain reliable and scalable for future innovations.

• 68486-77-1(3-[4-(benzyloxy)phenyl]propanal)
• 40167-10-0(4-(Phenylmethoxy)-benzeneacetaldehyde)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)