Cas no 5521-56-2 (6-Methylpyrazin-2-amine)
6-Methylpyrazin-2-amine Chemical and Physical Properties
Names and Identifiers
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- 6-Methylpyrazin-2-amine
- 2-Amino-6-methylpyrazine
- 6-Methylpyrazin-2-ylamine
- Pyrazinamine,6-methyl- (9CI)
- Pyrazine, 2-amino-6-methyl- (6CI,7CI,8CI)
- 6-Methyl-2-pyrazinamine
- FT-0649995
- UAOOJJPSCLNTOP-UHFFFAOYSA-N
- CS-W005339
- EN300-82524
- DTXSID80481792
- AM804036
- BCP23344
- AC-24530
- SCHEMBL67170
- Q-103333
- AB43812
- BL002901
- 6-Methyl-pyrazin-2-ylamine
- 2-amino-6-methylpyrazine, AldrichCPR
- 5521-56-2
- pyrazinamine, 6-methyl-
- PS-9272
- SCHEMBL5309165
- A7991
- SY021601
- MFCD08235193
- AKOS005259769
- Z1203578408
- A2992
- DB-031419
-
- MDL： MFCD08235193
- Inchi： 1S/C5H7N3/c1-4-2-7-3-5(6)8-4/h2-3H,1H3,(H2,6,8)
- InChI Key： UAOOJJPSCLNTOP-UHFFFAOYSA-N
- SMILES： N1C(=CN=CC=1C)N
Computed Properties
- Exact Mass: 109.06400
- Monoisotopic Mass: 109.063997236g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 8
- Rotatable Bond Count: 0
- Complexity: 74.1
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.4
- Topological Polar Surface Area: 51.8?2
Experimental Properties
- Density: 1.155
- Melting Point: 122.0 to 126.0 deg-C
- Boiling Point: 246°C at 760 mmHg
- Flash Point: 126°C
- Refractive Index: 1.582
- PSA: 51.80000
- LogP: 0.94840
6-Methylpyrazin-2-amine Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315-H319
- Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazard Category Code： 22
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Hazardous Material Identification：
- Storage Condition：Keep in dark place,Sealed in dry,2-8°C
6-Methylpyrazin-2-amine Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
6-Methylpyrazin-2-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A099001221-5g |
6-Methylpyrazin-2-amine |
5521-56-2 | 95% | 5g |
$210.60 | 2023-09-01 | |
| Alichem | A099001221-10g |
6-Methylpyrazin-2-amine |
5521-56-2 | 95% | 10g |
$396.00 | 2023-09-01 | |
| Alichem | A099001221-25g |
6-Methylpyrazin-2-amine |
5521-56-2 | 95% | 25g |
$780.00 | 2023-09-01 | |
| Fluorochem | 064915-250mg |
6-Methylpyrazin-2-amine |
5521-56-2 | 97% | 250mg |
￡17.00 | 2022-03-01 | |
| Fluorochem | 064915-1g |
6-Methylpyrazin-2-amine |
5521-56-2 | 97% | 1g |
￡40.00 | 2022-03-01 | |
| Fluorochem | 064915-5g |
6-Methylpyrazin-2-amine |
5521-56-2 | 97% | 5g |
￡170.00 | 2022-03-01 | |
| Fluorochem | 064915-10g |
6-Methylpyrazin-2-amine |
5521-56-2 | 97% | 10g |
￡314.00 | 2022-03-01 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | M825850-1g |
6-methylpyrazin-2-amine |
5521-56-2 | ≥95% | 1g |
197.00 | 2021-05-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-DR251-200mg |
2-Amino-6-Methylpyrazine |
5521-56-2 | 97% | 200mg |
110.0CNY | 2021-08-05 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-DR251-1g |
2-Amino-6-Methylpyrazine |
5521-56-2 | 97% | 1g |
340.0CNY | 2021-08-05 |
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6-Methylpyrazin-2-amine Related Literature
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Sankar K. Guchhait,Garima Priyadarshani,Nikhil M. Gulghane RSC Adv. 2016 6 56056
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2. Pteridine studies. Part V. The monosubstituted pteridinesAdrien Albert,D. J. Brown,H. C. S. Wood J. Chem. Soc. 1954 3832
Additional information on 6-Methylpyrazin-2-amine
Comprehensive Overview of 6-Methylpyrazin-2-amine (CAS No. 5521-56-2): Properties, Applications, and Research Insights
6-Methylpyrazin-2-amine (CAS No. 5521-56-2) is a heterocyclic organic compound belonging to the pyrazine family, characterized by a methyl group at the 6-position and an amino group at the 2-position of the pyrazine ring. This structurally unique molecule has garnered significant attention in pharmaceutical and agrochemical research due to its potential as a building block for bioactive molecules. The compound's molecular formula (C5H7N3) and molecular weight (109.13 g/mol) make it a versatile intermediate in synthetic chemistry.
Recent studies highlight the growing interest in 6-Methylpyrazin-2-amine derivatives for their role in drug discovery, particularly in the development of kinase inhibitors and antimicrobial agents. Researchers are exploring its utility in structure-activity relationship (SAR) studies to optimize therapeutic efficacy. The compound's hydrogen bonding capacity and electron-rich aromatic system contribute to its interactions with biological targets, making it a valuable scaffold in medicinal chemistry.
In the context of green chemistry, 5521-56-2 has been investigated for its potential in sustainable synthesis routes. A 2023 study published in the Journal of Organic Chemistry demonstrated its use in catalyzed cross-coupling reactions with reduced environmental impact. This aligns with the industry's shift toward eco-friendly intermediates, addressing frequent search queries like "sustainable heterocyclic compounds" and "green synthesis of pyrazine derivatives."
The physicochemical properties of 6-Methylpyrazin-2-amine include a melting point range of 98-102°C and moderate water solubility, which influence its formulation strategies. Analytical techniques such as HPLC (High-Performance Liquid Chromatography) and LC-MS (Liquid Chromatography-Mass Spectrometry) are commonly employed for its characterization, reflecting laboratory professionals' search trends for "pyrazine amine analysis methods."
Emerging applications in material science have expanded the compound's relevance. Its incorporation into coordination polymers and metal-organic frameworks (MOFs) has shown promise in gas storage and catalysis, topics frequently searched in academic databases. The amino group's nucleophilicity enables post-synthetic modifications, a key advantage for tailored material design.
Quality control protocols for CAS No. 5521-56-2 emphasize spectroscopic purity verification (≥98% by 1H NMR) and residual solvent analysis, addressing regulatory concerns in pharmaceutical manufacturing. These details respond to common queries like "pyrazine amine purity standards" and "GMP-compliant heterocyclic intermediates."
Ongoing research explores the compound's metabolic stability and toxicological profile, critical for preclinical development. Computational modeling studies predict favorable ADME properties (Absorption, Distribution, Metabolism, Excretion), making it a candidate for further optimization in lead compound development.
In summary, 6-Methylpyrazin-2-amine represents a multifaceted chemical entity with expanding applications across drug development, materials engineering, and sustainable chemistry. Its structural modularity and synthetic accessibility continue to drive innovation, positioning it as a compound of enduring scientific interest.
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