• 1. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 2. Fate of single walled carbon nanotubes in wetland ecosystems?
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• 3. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 5. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Comprehensive Overview of 1-(3-Acetyl-2-hydroxy-5-methyl-phenyl)ethanone (CAS No. 55108-28-6): Properties, Applications, and Industry Insights

1-(3-Acetyl-2-hydroxy-5-methyl-phenyl)ethanone, with the CAS number 55108-28-6, is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This acetyl-substituted hydroxy phenyl ketone derivative is known for its unique structural properties, making it a valuable intermediate in synthetic chemistry. Its molecular formula, C₁₁H₁₂O₃, highlights a balance of aromaticity and functional groups, which contribute to its reactivity and versatility.

In recent years, the demand for high-purity ketone derivatives like 1-(3-Acetyl-2-hydroxy-5-methyl-phenyl)ethanone has surged, driven by advancements in drug discovery and material science. Researchers are particularly interested in its potential as a building block for bioactive molecules, especially in designing anti-inflammatory and antioxidant agents. The compound's hydroxy and acetyl groups offer sites for further chemical modifications, enabling the creation of tailored derivatives for specific applications.

The synthesis of CAS 55108-28-6 typically involves Friedel-Crafts acylation or selective oxidation methods, which are widely discussed in academic literature. Optimizing these processes to achieve high yield and minimal byproducts remains a key focus for industrial chemists. Additionally, the compound's solubility in organic solvents (e.g., ethanol, DMSO) and melting point range (often reported between 120–125°C) are critical parameters for its handling and application.

From an environmental perspective, sustainable synthesis routes for 1-(3-Acetyl-2-hydroxy-5-methyl-phenyl)ethanone are gaining traction. Green chemistry initiatives emphasize catalyst recycling and energy-efficient protocols, aligning with global trends toward eco-friendly manufacturing. This aligns with frequent search queries such as "green synthesis of ketone intermediates" and "biodegradable aromatic compounds," reflecting growing consumer and regulatory pressures.

In the pharmaceutical sector, 55108-28-6 is explored for its role in prodrug development and enzyme inhibition studies. Its structural similarity to natural phenolic compounds has sparked interest in nutraceutical formulations, particularly in blends targeting oxidative stress management. These applications resonate with trending topics like "natural-derived therapeutics" and "precision medicine."

Analytical characterization of 1-(3-Acetyl-2-hydroxy-5-methyl-phenyl)ethanone relies heavily on HPLC, NMR spectroscopy, and mass spectrometry. Purity thresholds (>98%) are often required for commercial batches, underscoring the importance of quality control in fine chemicals. Discussions on platforms like ResearchGate frequently address "spectral data interpretation for acetylated phenols" and "scalable purification techniques," highlighting the compound's technical relevance.

Market analysts note steady growth in the global ketone intermediates market, where CAS 55108-28-6 occupies a niche segment. Key drivers include R&D investments in specialty chemicals and the expansion of contract manufacturing organizations (CMOs). Suppliers increasingly emphasize regulatory compliance (e.g., REACH, USP standards) and supply chain transparency to meet buyer expectations.

Future research directions may explore computational modeling of 55108-28-6 derivatives to predict their ADMET properties (Absorption, Distribution, Metabolism, Excretion, Toxicity). Such studies could unlock new applications in personalized medicine or functional materials, areas frequently searched in conjunction with "AI-driven chemical design."

• 699-91-2(2-Acetyl-6-methylphenol)
• 55108-29-7(Benzaldehyde, 3-acetyl-2-hydroxy-)
• 118-93-4(2'-Hydroxyacetophenone)
• 1450-72-2(2'-Hydroxy-5'-methylacetophenone)
• 1198-66-9(1-(2-hydroxy-3,5-dimethylphenyl)ethan-1-one)
• 104809-67-8(Ethanone,1-(2-hydroxyphenyl)-, labeled with carbon-14 (9CI))
• 24539-92-2(5'-Ethyl-2’-hydroxyacetophenone)
• 51366-25-7(Benzenemethanol,3,4-dichloro-2-(trichloromethyl)-, 1-acetate)
• 1189865-36-8(2-Hydroxyacetophenone-d7)
• 19434-30-1((2-hydroxyphenyl)(4-methylphenyl)methanone)