Cas no 5500-21-0 (Cyclopropanecarbonitrile)

Cyclopropanecarbonitrile (CAS 5500-21-0) is a versatile organic compound featuring a cyclopropane ring bonded to a nitrile functional group. Its strained three-membered ring structure imparts unique reactivity, making it valuable in synthetic organic chemistry, particularly in cycloaddition reactions and as a building block for pharmaceuticals and agrochemicals. The nitrile group offers further functionalization potential, enabling conversion to carboxylic acids, amines, or heterocycles. This compound is characterized by its high purity and stability under standard conditions, ensuring consistent performance in research and industrial applications. Its compact structure also facilitates studies in steric and electronic effects in small-ring systems.
Cyclopropanecarbonitrile structure
Cyclopropanecarbonitrile structure
Product Name:Cyclopropanecarbonitrile
CAS No:5500-21-0
MF:C4H5N
MW:67.0892007350922
MDL:MFCD00001269
CID:45967
PubChem ID:79637
Update Time:2025-11-02

Cyclopropanecarbonitrile Chemical and Physical Properties

Names and Identifiers

    • Cyclopropyl cyanide
    • Cyclopropanecarbonitrile
    • Cyanocyclopropane~Cyclopropyl cyanide
    • Cyclopropane Cyanide
    • 1-cyanocyclopropane
    • CPCN
    • CYANOCYCLOPROPANE
    • cyclopropancarbonitril
    • Cyclopropanecarbonit
    • cyclopropanenitrile
    • cyclopropylcarbonitrile
    • CYCLOPROPYLNITRILE
    • Cyclopropane carbonitrile
    • AUQDITHEDVOTCU-UHFFFAOYSA-N
    • Cyclopropyl cyanide, 98%
    • cyclopropylcyanide
    • cyclopropankohlenitrile
    • KSC270K3H
    • Cyclopropanecarbonitrile, 98%
    • Cyclopropanecarboxylic acid nitrile
    • Q5198968
    • NSC 60191
    • MFCD00001269
    • Z247612572
    • FT-0602346
    • AKOS000121165
    • F0001-1444
    • 5500-21-0
    • NS00033219
    • InChI=1/C4H5N/c5-3-4-1-2-4/h4H,1-2H
    • PD065650
    • EINECS 226-836-8
    • AFU99GZS5D
    • NSC-60191
    • DTXSID1063936
    • NSC60191
    • A830440
    • EN300-27822
    • UNII-AFU99GZS5D
    • BP-10177
    • AMY3403
    • CS-D1406
    • AI3-07023
    • Cyclopropanecarbonitrile,98%
    • STK328117
    • DTXCID8041824
    • DB-007375
    • MDL: MFCD00001269
    • Inchi: 1S/C4H5N/c5-3-4-1-2-4/h4H,1-2H2
    • InChI Key: AUQDITHEDVOTCU-UHFFFAOYSA-N
    • SMILES: N#CC1CC1
    • BRN: 635790

Computed Properties

  • Exact Mass: 67.04220
  • Monoisotopic Mass: 67.042199164g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 5
  • Rotatable Bond Count: 0
  • Complexity: 72.9
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.3
  • Topological Polar Surface Area: 23.8

Experimental Properties

  • Color/Form: Not determined
  • Density: 0.911?g/mL?at 25?°C(lit.)
  • Boiling Point: 135°C
  • Flash Point: Fahrenheit: 104 ° f
    Celsius: 40 ° c
  • Refractive Index: n20/D 1.421(lit.)
  • Water Partition Coefficient: Miscible with water.
  • PSA: 23.79000
  • LogP: 0.91998
  • Solubility: Not determined

Cyclopropanecarbonitrile Security Information

Cyclopropanecarbonitrile Customs Data

  • HS CODE:29269095
  • Customs Data:

    China Customs Code:

    2926909090

    Overview:

    2926909090 Other nitrile based compounds. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Cyclopropanecarbonitrile Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:5500-21-0)Cyclopropanecarbonitrile
Order Number:LE2206;LE3457298
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:42
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Suzhou Senfeida Chemical Co., Ltd
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(CAS:5500-21-0)Cyclopropanecarbonitrile
Order Number:sfd20240
Stock Status:in Stock
Quantity:200KG
Purity:99%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally

Additional information on Cyclopropanecarbonitrile

Cyclopropanecarbonitrile (CAS No. 5500-21-0): Properties, Applications, and Market Insights

Cyclopropanecarbonitrile (CAS No. 5500-21-0) is a versatile organic compound with a unique cyclopropane ring structure and a nitrile functional group. This compound has garnered significant attention in recent years due to its applications in pharmaceuticals, agrochemicals, and specialty chemicals. The growing demand for cyclopropane derivatives in drug discovery and material science has made Cyclopropanecarbonitrile a subject of interest for researchers and industry professionals alike.

One of the most frequently asked questions about Cyclopropanecarbonitrile is: "What are the key properties of Cyclopropanecarbonitrile?" This compound is characterized by its high reactivity, which stems from the strained three-membered cyclopropane ring. The nitrile group (-CN) adds to its versatility, making it a valuable building block in organic synthesis. Recent studies have focused on its stereochemical properties and potential as a precursor for more complex molecules.

In the pharmaceutical industry, Cyclopropanecarbonitrile derivatives are increasingly important. Many researchers are investigating "How is Cyclopropanecarbonitrile used in drug development?" The answer lies in its ability to serve as a key intermediate for various bioactive compounds. The cyclopropyl moiety is particularly valuable in medicinal chemistry due to its ability to modify the pharmacokinetic properties of drug candidates. Several studies have demonstrated its utility in creating molecules with improved metabolic stability and target selectivity.

The agrochemical sector has also shown growing interest in Cyclopropanecarbonitrile applications. With the global push for more sustainable crop protection solutions, chemists are exploring cyclopropane-containing compounds as potential active ingredients. The unique structural features of Cyclopropanecarbonitrile offer possibilities for developing novel pesticides with reduced environmental impact. This aligns well with current trends in green chemistry and sustainable agriculture.

From a synthetic chemistry perspective, one common query is: "What are the best methods for preparing Cyclopropanecarbonitrile?" Several synthetic routes have been developed, including the cyclopropanation of acrylonitrile derivatives and the functionalization of pre-formed cyclopropane rings. Recent advancements in catalytic methods have improved the efficiency of these processes, making Cyclopropanecarbonitrile more accessible for research and industrial applications.

The material science field has begun exploring Cyclopropanecarbonitrile-based polymers. The compound's rigid structure and polar nitrile group make it an interesting monomer for creating specialty materials. Researchers are particularly interested in its potential for developing high-performance polymers with unique thermal and mechanical properties. This application area has gained momentum with the increasing demand for advanced materials in electronics and aerospace industries.

Market analysis reveals that the demand for Cyclopropanecarbonitrile is steadily increasing. Industry reports suggest that the compound's market growth is driven by its expanding applications in pharmaceutical intermediates and specialty chemicals. The Asia-Pacific region, particularly China and India, has emerged as a significant producer and consumer of cyclopropane derivatives, reflecting the global shift in chemical manufacturing.

Safety considerations for handling Cyclopropanecarbonitrile are another important topic. While not classified as hazardous under standard conditions, proper laboratory practices should always be followed when working with this compound. Many safety data sheets emphasize the importance of using appropriate personal protective equipment and working in well-ventilated areas when handling nitrile-containing compounds.

Future research directions for Cyclopropanecarbonitrile are likely to focus on developing more efficient synthetic methods and exploring novel applications. The compound's unique combination of a strained ring system and reactive functional group continues to inspire innovation across multiple chemical disciplines. As sustainable chemistry gains prominence, green synthesis approaches for cyclopropane derivatives will probably receive increased attention from both academic and industrial researchers.

In conclusion, Cyclopropanecarbonitrile (CAS No. 5500-21-0) represents a fascinating and valuable chemical building block with diverse applications. Its importance in pharmaceutical research, agrochemical development, and material science underscores the ongoing relevance of small-ring compounds in modern chemistry. As research continues to uncover new possibilities for this versatile molecule, its role in addressing current chemical challenges is expected to grow significantly in the coming years.

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Suzhou Senfeida Chemical Co., Ltd
(CAS:5500-21-0)Cyclopropanecarbonitrile
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