• 1. Excimer–monomer switch: a reaction-based approach for selective detection of fluoride?
  Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
• 2. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 3. Excimer formation effects and trap-assisted charge recombination loss channels in organic solar cells of perylene diimide dimer acceptors?
  Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
• 4. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
• 5. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203

Comprehensive Guide to 4-Cyclopentylbenzenesulfonyl chloride (CAS No. 54997-94-3): Properties, Applications, and Industry Insights

4-Cyclopentylbenzenesulfonyl chloride (CAS No. 54997-94-3) is a specialized sulfonyl chloride derivative widely recognized for its role in organic synthesis and pharmaceutical intermediates. This compound features a cyclopentyl group attached to a benzenesulfonyl chloride core, making it a versatile reagent for amide bond formation, sulfonylation reactions, and peptide coupling. Its unique structure contributes to its reactivity, enabling applications in drug discovery, material science, and agrochemical research.

In recent years, the demand for high-purity sulfonyl chlorides like 4-Cyclopentylbenzenesulfonyl chloride has surged due to advancements in small-molecule therapeutics and bioconjugation techniques. Researchers frequently search for "sulfonyl chloride stability," "benzenesulfonyl chloride derivatives," and "CAS 54997-94-3 suppliers," reflecting its industrial relevance. The compound’s low moisture tolerance and storage conditions are also common topics in technical discussions.

From a synthetic perspective, 4-Cyclopentylbenzenesulfonyl chloride is prized for its ability to introduce the sulfonyl functional group into target molecules. This property is critical in designing enzyme inhibitors and protease-targeting drugs, aligning with trends in precision medicine. Its compatibility with green chemistry principles—such as reduced solvent waste—further enhances its appeal in sustainable research.

The compound’s spectroscopic data (e.g., NMR, IR, and mass spectrometry profiles) is well-documented, aiding in quality control and batch consistency. Analytical chemists often inquire about "54997-94-3 characterization" or "4-Cyclopentylbenzenesulfonyl chloride HPLC methods," underscoring the need for reliable protocols. Proper handling under inert atmospheres and cold storage is recommended to maintain its efficacy.

Emerging applications include its use in photocatalysis and cross-coupling reactions, where its electron-withdrawing nature improves reaction yields. As the pharmaceutical industry shifts toward fragment-based drug design, 4-Cyclopentylbenzenesulfonyl chloride serves as a key building block for scaffold diversification. Its role in biomarker labeling also intersects with diagnostic imaging innovations.

For procurement specialists, factors like "bulk pricing for 54997-94-3" and "custom synthesis options" are critical. The compound’s regulatory compliance (e.g., REACH and GMP standards) ensures its suitability for global markets. Future research may explore its potential in polymeric materials or catalysis, expanding its utility beyond traditional domains.

• 54997-92-1(4-n-butylbenzene-1-sulfonyl chloride)
• 52499-14-6(Benzenesulfonylchloride, 4-dodecyl-)
• 56354-57-5(4-Cyclohexylbenzene-1-sulfonyl chloride)
• 73948-18-2(4-PENTYLBENZENE-1-SULFONYL CHLORIDE)
• 146949-07-7(4-n-Propylbenzenesulfonyl chloride)
• 61551-50-6(Benzenesulfonyl chloride, 4-cyclododecyl-)
• 54997-90-9(4-(propan-2-yl)benzenesulfonyl chloride)
• 339370-45-5(4-Isobutylbenzenesulfonyl Chloride)
• 169677-20-7(4-TERT-AMYLBENZENESULFONYL CHLORIDE)
• 54997-91-0(Benzenesulfonyl chloride, 4-octyl-)