Cas no 54584-24-6 (2-Methylbenzofuran-6-ol)

2-Methylbenzofuran-6-ol is a benzofuran derivative characterized by the presence of a hydroxyl group at the 6-position and a methyl substituent at the 2-position of the benzofuran core. This compound is of interest in organic synthesis and pharmaceutical research due to its structural framework, which serves as a key intermediate in the development of bioactive molecules. Its phenolic functionality allows for further derivatization, enhancing its utility in constructing complex heterocyclic systems. The methyl group contributes to increased lipophilicity, potentially improving membrane permeability in biological applications. The compound is typically handled under controlled conditions to preserve its reactive hydroxyl group.
2-Methylbenzofuran-6-ol structure
2-Methylbenzofuran-6-ol structure
Product Name:2-Methylbenzofuran-6-ol
CAS No:54584-24-6
MF:C9H8O2
MW:148.158622741699
MDL:MFCD09908136
CID:1027808
PubChem ID:12203498
Update Time:2025-10-23

2-Methylbenzofuran-6-ol Chemical and Physical Properties

Names and Identifiers

    • 2-Methylbenzofuran-6-ol
    • 2-Methyl-1-benzofuran-6-ol
    • 6-hydroxy-2-methylbenzofuran
    • AKOS006311470
    • CS-0095467
    • CS-16335
    • 6Hydroxy-2-methylbenzofuran
    • DTXSID10480314
    • 54584-24-6
    • 2-METHYL-BENZOFURAN-6-OL
    • A870414
    • 2 - Methylbenzofuran - 6 - ol
    • AMY23683
    • SCHEMBL2269879
    • F21500
    • ASUDREWVUSTLJP-UHFFFAOYSA-N
    • 6-Hydroxy-2-methyl-benzofuran
    • AC-35347
    • MDL: MFCD09908136
    • Inchi: 1S/C9H8O2/c1-6-4-7-2-3-8(10)5-9(7)11-6/h2-5,10H,1H3
    • InChI Key: ASUDREWVUSTLJP-UHFFFAOYSA-N
    • SMILES: O1C(C)=CC2C=CC(=CC1=2)O

Computed Properties

  • Exact Mass: 148.052429494g/mol
  • Monoisotopic Mass: 148.052429494g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 147
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.4
  • Topological Polar Surface Area: 33.4?2

Experimental Properties

  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 133.2±10.0 °C at 760 mmHg
  • Flash Point: 34.3±19.0 °C
  • Vapor Pressure: 7.0±0.3 mmHg at 25°C

2-Methylbenzofuran-6-ol Security Information

2-Methylbenzofuran-6-ol Pricemore >>

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Additional information on 2-Methylbenzofuran-6-ol

2-Methylbenzofuran-6-ol: A Comprehensive Overview

The compound 2-Methylbenzofuran-6-ol, identified by the CAS number 54584-24-6, is a fascinating organic molecule with significant potential in various fields. This compound belongs to the class of benzofurans, which are aromatic heterocyclic compounds consisting of a benzene ring fused to a furan ring. The presence of a methyl group at the 2-position and a hydroxyl group at the 6-position introduces unique chemical properties that make it an interesting subject of study.

Recent advancements in synthetic chemistry have enabled researchers to explore novel methods for the synthesis of 2-Methylbenzofuran-6-ol. One such approach involves the use of transition metal catalysts, which not only enhance reaction efficiency but also allow for better control over the stereochemistry of the product. These methods have been documented in several high-impact journals, highlighting their importance in organic synthesis.

The structural features of 2-Methylbenzofuran-6-ol contribute significantly to its reactivity and stability. The conjugation between the aromatic ring and the furan moiety results in a resonance-stabilized structure, which is crucial for its participation in various chemical reactions. Moreover, the hydroxyl group at the 6-position imparts hydrophilic properties, making it suitable for applications in pharmaceuticals and materials science.

In terms of applications, 2-Methylbenzofuran-6-ol has shown promise in the development of bioactive compounds. Studies have demonstrated its potential as an antioxidant and anti-inflammatory agent, making it a valuable candidate for drug discovery. Additionally, its ability to form stable complexes with metal ions has opened avenues for its use in catalysis and sensor technology.

The synthesis and characterization of 2-Methylbenzofuran-6-ol have been extensively studied using advanced analytical techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. These studies provide insights into its molecular structure and reactivity, further enhancing our understanding of this compound.

In conclusion, 2-Methylbenzofuran-6-ol is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical properties and potential for further research make it an essential topic for scientists and researchers alike.

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