Cas no 5434-21-9 (4-Aminophthalic acid)

4-Aminophthalic acid (CAS 5466-84-2) is an aromatic compound featuring both amino and carboxylic acid functional groups on a phthalic acid backbone. This structure imparts versatility in organic synthesis, particularly as a precursor for dyes, fluorescent probes, and coordination polymers. Its dual functionality enables participation in condensation, amidation, and complexation reactions, making it valuable in materials science and pharmaceutical intermediates. The compound exhibits moderate solubility in polar solvents, facilitating its use in aqueous or organic reaction systems. Its rigid aromatic core contributes to thermal stability, while the electron-donating amino group enhances reactivity in electrophilic substitutions. Proper handling is advised due to potential sensitivity to light and heat.
4-Aminophthalic acid structure
4-Aminophthalic acid structure
Product Name:4-Aminophthalic acid
CAS No:5434-21-9
MF:C8H7NO4
MW:181.145482301712
MDL:MFCD00013985
CID:45866
PubChem ID:24874438
Update Time:2025-08-02

4-Aminophthalic acid Chemical and Physical Properties

Names and Identifiers

    • 4-Aminophthalic acid
    • Tranexsmic Acid
    • 1-amino-3,4-dicarboxy-benzene
    • 4-Amino-1,2-benzenedicarboxylic acid
    • 4-aminobenzene-1,2-dicarboxylic acid
    • 4-aminobenzene-1,2-dioic acid
    • 4-amino-phthalic acid
    • 4-Amino-phthalsaeure
    • 5-Aminophthalic acid
    • 1,2-Benzenedicarboxylic acid, 4-amino-
    • 1,2 Benzenedicarboxylicacid, 4-amino-
    • 4-AMINO PHTHALIC ACID
    • 4-Aminophthalic Acid(Contains 3-Aminophthalic Acid)
    • PubChem16853
    • KSC270I4N
    • ghl.PD_Mitscher_leg0.1208
    • OXSANYRLJHSQEP-UHFFFAOYSA-N
    • NSC15742
    • CS-0010092
    • EINECS 226-596-4
    • Z276600422
    • 3-AMINO-3-(4-DIETHYLAMINO-PHENYL)-PROPIONICACID
    • 4-Amino-1,2-benzenedicarboxylic acid;1,2-Benzenedicarboxylic acid, 4-amino-
    • W-105641
    • 4-Aminophthalic acid, 97%
    • 5434-21-9
    • NSC-15742
    • AC-23591
    • 4-Aminophthalicacid
    • GS-6117
    • H10264
    • CHEMBL3278349
    • FT-0617601
    • TZ6K337ZYS
    • NSC 15742
    • AKOS000280910
    • MFCD00013985
    • EN300-57011
    • BCP30626
    • GM7
    • NS00033053
    • DTXSID8063880
    • SY013972
    • SCHEMBL231377
    • 4-amino-2-benzenedicarboxylicacid
    • A1512
    • DB-052543
    • MDL: MFCD00013985
    • Inchi: 1S/C8H7NO4/c9-4-1-2-5(7(10)11)6(3-4)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)
    • InChI Key: OXSANYRLJHSQEP-UHFFFAOYSA-N
    • SMILES: OC(C1C=C(C=CC=1C(=O)O)N)=O
    • BRN: 2723405

Computed Properties

  • Exact Mass: 181.03800
  • Monoisotopic Mass: 181.037508
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 2
  • Complexity: 228
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: 0.7
  • Topological Polar Surface Area: 101

Experimental Properties

  • Color/Form: Yellowish powder, dark in light.
  • Density: 1.6±0.1 g/cm3
  • Melting Point: 344?°C (dec.) (lit.)
  • Boiling Point: 465.1℃ at 760 mmHg
  • Flash Point: 235.1℃
  • PSA: 100.62000
  • LogP: 1.24640
  • Solubility: Slightly soluble in ethanol, insoluble in water.
  • Sensitiveness: Sensitive to air
  • Vapor Pressure: 0.0±1.2 mmHg at 25°C

4-Aminophthalic acid Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26-S36
  • Hazardous Material Identification: Xi
  • Safety Term:S26;S36
  • Risk Phrases:R36/37/38
  • TSCA:Yes
  • Storage Condition:Argon filled storage

4-Aminophthalic acid Customs Data

  • HS CODE:2922499990
  • Customs Data:

    China Customs Code:

    2922499990

    Overview:

    2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    P.Imported animals and plants\Quarantine of animal and plant products
    Q.Outbound animals and plants\Quarantine of animal and plant products
    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

4-Aminophthalic acid Pricemore >>

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4-Aminophthalic acid Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5434-21-9)4-Aminophthalic acid
Order Number:A1205298
Stock Status:in Stock
Quantity:500g/1kg
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:57
Price ($):239.0/408.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:5434-21-9)4-氨基鄰苯二甲酸
Order Number:LE26635638;LE6460
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:56
Price ($):discuss personally
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier Audited Supplier
(CAS:5434-21-9)4-Aminophthalic acid
Order Number:AC040
Stock Status:in Stock
Quantity:25kg
Purity:98%
Pricing Information Last Updated:Monday, 18 August 2025 09:27
Price ($):discuss personally
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
Audited Supplier Audited Supplier
(CAS:5434-21-9)4-Aminophthalic acid
Order Number:JOX-046
Stock Status:in Stock
Quantity:25KG
Purity:98%
Pricing Information Last Updated:Tuesday, 15 July 2025 15:40
Price ($):

Additional information on 4-Aminophthalic acid

4-Aminophthalic Acid (CAS No. 5434-21-9): Properties, Applications, and Market Insights

4-Aminophthalic acid (CAS No. 5434-21-9) is an important organic compound widely used in pharmaceuticals, dyes, and advanced material synthesis. This aromatic carboxylic acid derivative is known for its unique chemical properties, making it a valuable intermediate in various industrial and research applications. In this article, we will explore the physical and chemical properties of 4-Aminophthalic acid, its key applications, and the latest market trends.

The molecular formula of 4-Aminophthalic acid is C8H7NO4, and it features both an amino group (–NH2) and two carboxyl groups (–COOH) attached to a benzene ring. This structure grants it excellent reactivity, particularly in condensation and polymerization reactions. Researchers often utilize 4-Aminophthalic acid CAS 5434-21-9 as a building block for synthesizing complex molecules, including fluorescent dyes and pharmaceutical intermediates.

One of the most notable applications of 4-Aminophthalic acid is in the production of high-performance dyes. Due to its ability to form stable chromophores, it is frequently used in textile and ink manufacturing. Additionally, its fluorescence properties make it suitable for optical brighteners and sensor materials. Recent advancements in nanotechnology have also highlighted its role in developing novel organic electronic materials, a trending topic in material science.

In the pharmaceutical industry, 4-Aminophthalic acid derivatives are explored for their potential in drug design. Scientists are investigating its use in creating bioactive molecules with antimicrobial and anti-inflammatory properties. Given the rising demand for new therapeutic agents, this compound has gained attention in medicinal chemistry research.

The market for 4-Aminophthalic acid has seen steady growth, driven by increasing demand from the dye and pharmaceutical sectors. Manufacturers are focusing on sustainable synthesis methods to reduce environmental impact, aligning with the global push toward green chemistry. This shift has made CAS 5434-21-9 a subject of interest in eco-friendly chemical production.

For researchers and industry professionals, understanding the stability and handling of 4-Aminophthalic acid is crucial. While it is not classified as hazardous under standard conditions, proper storage in a cool, dry environment is recommended to maintain its integrity. Analytical techniques such as HPLC and NMR are commonly employed to verify its purity.

In conclusion, 4-Aminophthalic acid (5434-21-9) remains a versatile compound with expanding applications in modern chemistry. Its role in dyes, pharmaceuticals, and advanced materials underscores its industrial significance. As research continues, we can expect further innovations leveraging its unique chemical properties.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:5434-21-9)4-Aminophthalic acid
A1205298
Purity:99%/99%
Quantity:500g/1kg
Price ($):239.0/408.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:5434-21-9)4-氨基鄰苯二甲酸
LE26635638;LE6460
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email