Cas no 5429-01-6 (4-Methylquinolin-6-ol)

4-Methylquinolin-6-ol is a heterocyclic organic compound featuring a quinoline backbone substituted with a methyl group at the 4-position and a hydroxyl group at the 6-position. This structure imparts unique chemical properties, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Its hydroxyl group enhances reactivity for further functionalization, while the methyl group contributes to stability and solubility in organic solvents. The compound is particularly useful in the development of bioactive molecules, including potential antimicrobial and anticancer agents. Its well-defined structure and purity ensure consistent performance in research and industrial applications, supporting advancements in medicinal chemistry and material science.
4-Methylquinolin-6-ol structure
4-Methylquinolin-6-ol structure
Product Name:4-Methylquinolin-6-ol
CAS No:5429-01-6
MF:C10H9NO
MW:159.184562444687
CID:940506
PubChem ID:224664
Update Time:2025-11-02

4-Methylquinolin-6-ol Chemical and Physical Properties

Names and Identifiers

    • 4-Methylquinolin-6-ol
    • AC1L5DGQ; NSC13344; 6-Hydroxy-4-methyl-chinolin; SureCN3272504; 4-methyl-quinolin-6-ol; 6-hydroxy-4-methylquinoline; CTK5A0358; AC1Q7AHF; AR-1G3829; 6-Hydroxy-lepidin; 4-Methyl-chinolin-6-ol;
    • CS-0088087
    • F2147-8681
    • AKOS022183771
    • 6-hydroxylepidine
    • NSC13344
    • DB-154307
    • 4-methyl-quinolin-6-ol
    • NSC-13344
    • SB68371
    • YSCLQXFVKXKSMU-UHFFFAOYSA-N
    • 5429-01-6
    • 6-Hydroxy4-Methylquinoline
    • G74536
    • EN300-1716814
    • DTXSID20279599
    • 6-Hydroxy-4-Methylquinoline
    • 4-methyl-6-quinolinol
    • SCHEMBL3272504
    • Inchi: 1S/C10H9NO/c1-7-4-5-11-10-3-2-8(12)6-9(7)10/h2-6,12H,1H3
    • InChI Key: YSCLQXFVKXKSMU-UHFFFAOYSA-N
    • SMILES: OC1C=CC2C(C=1)=C(C)C=CN=2

Computed Properties

  • Exact Mass: 159.06847
  • Monoisotopic Mass: 159.068
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 160
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.3
  • Topological Polar Surface Area: 33.1?2

Experimental Properties

  • Density: 1.21
  • Boiling Point: 330°C at 760 mmHg
  • Flash Point: 153.4°C
  • Refractive Index: 1.666
  • PSA: 33.12
  • LogP: 2.24880

4-Methylquinolin-6-ol Pricemore >>

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Additional information on 4-Methylquinolin-6-ol

4-Methylquinolin-6-ol (CAS No. 5429-01-6): Properties, Applications, and Market Insights

4-Methylquinolin-6-ol (CAS No. 5429-01-6) is a heterocyclic organic compound belonging to the quinoline family. This compound, also known as 6-hydroxy-4-methylquinoline, has garnered significant attention in recent years due to its versatile applications in pharmaceuticals, agrochemicals, and material science. Researchers and industry professionals frequently search for terms like "4-Methylquinolin-6-ol synthesis", "6-hydroxy-4-methylquinoline applications", and "CAS 5429-01-6 properties", reflecting the growing interest in this compound.

The molecular structure of 4-Methylquinolin-6-ol features a quinoline backbone with a methyl group at the 4-position and a hydroxyl group at the 6-position. This unique arrangement contributes to its distinct chemical properties, including moderate solubility in organic solvents and characteristic fluorescence properties. Recent studies have explored its potential as a fluorescence probe in biochemical assays, addressing the current research trend toward developing novel analytical tools for life sciences.

In the pharmaceutical sector, 4-Methylquinolin-6-ol serves as a valuable intermediate in the synthesis of various bioactive molecules. The compound's quinoline core structure makes it particularly interesting for drug discovery, especially in the development of antimicrobial agents and central nervous system (CNS) drugs. This aligns with the increasing global demand for new therapeutic compounds, as evidenced by frequent searches for "quinoline derivatives in medicine" and "4-Methylquinolin-6-ol biological activity".

The material science applications of 6-hydroxy-4-methylquinoline have gained prominence in recent years. Its ability to coordinate with metal ions makes it useful in the development of organic semiconductors and luminescent materials, topics that are currently trending in advanced materials research. The compound's potential in organic electronics responds to the growing interest in sustainable and efficient electronic components.

From a synthetic chemistry perspective, 4-Methylquinolin-6-ol can be prepared through various routes, including the Skraup synthesis or modified Doebner-Miller reactions. Recent advancements in green chemistry approaches have led to more environmentally friendly synthesis methods, addressing the industry's shift toward sustainable practices. Search queries like "eco-friendly synthesis of 4-Methylquinolin-6-ol" reflect this emerging trend among chemical researchers.

The global market for 4-Methylquinolin-6-ol has shown steady growth, driven by its expanding applications in multiple industries. Market analysis reveals increasing demand from the Asia-Pacific region, particularly from pharmaceutical and specialty chemical manufacturers. Quality specifications for CAS 5429-01-6 typically require high purity levels (≥98%), with strict control over impurities to meet the requirements of end-use applications.

Analytical characterization of 6-hydroxy-4-methylquinoline typically involves techniques such as HPLC, GC-MS, and NMR spectroscopy. These methods ensure product quality and consistency, which are critical factors for industrial users. The compound's stability under various storage conditions is another frequently searched topic, with many users inquiring about "4-Methylquinolin-6-ol storage recommendations" and "shelf life of CAS 5429-01-6".

Recent patent literature indicates growing intellectual property activity surrounding 4-Methylquinolin-6-ol derivatives, particularly in pharmaceutical applications. This innovation trend corresponds with the compound's structural versatility, allowing for diverse modifications to enhance specific properties. The scientific community continues to explore novel derivatives through searches for "4-Methylquinolin-6-ol structure-activity relationships" and "quinoline-based drug design".

Safety considerations for handling 4-Methylquinolin-6-ol follow standard laboratory practices for organic compounds. While not classified as highly hazardous, proper personal protective equipment (PPE) is recommended when working with this chemical. The increasing focus on workplace safety in chemical industries has made "6-hydroxy-4-methylquinoline safety data" a common search term among professionals.

Future research directions for CAS 5429-01-6 may include exploring its potential in emerging fields such as metal-organic frameworks (MOFs) and catalysis. The compound's ability to function as a ligand for various metal ions positions it as an interesting candidate for these applications. These developments align with current scientific trends toward multifunctional materials and sustainable chemical processes.

In conclusion, 4-Methylquinolin-6-ol represents an important building block in modern chemistry with diverse applications across multiple industries. Its continued relevance is evidenced by sustained research interest and market demand. As scientific understanding of this compound deepens, new applications are likely to emerge, further solidifying its position as a valuable chemical entity in both academic and industrial settings.

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