Cas no 54244-76-7 (N-cyclopentyl-N-ethylacetamide)

N-Cyclopentyl-N-ethylacetamide is a specialized organic compound featuring a cyclopentyl and ethyl substituent on the nitrogen atom of an acetamide backbone. This structure imparts unique steric and electronic properties, making it valuable in synthetic chemistry as an intermediate or building block for pharmaceuticals, agrochemicals, and specialty materials. Its amide functionality enhances stability while allowing for further derivatization. The cyclopentyl group contributes to lipophilicity, potentially improving bioavailability in drug design applications. The compound is typically synthesized under controlled conditions to ensure high purity, making it suitable for research and industrial applications requiring precise molecular frameworks. Proper handling and storage are recommended due to its reactivity profile.
N-cyclopentyl-N-ethylacetamide structure
54244-76-7 structure
Product Name:N-cyclopentyl-N-ethylacetamide
CAS No:54244-76-7
MF:C9H17NO
MW:155.237382650375
CID:940209
PubChem ID:558466
Update Time:2025-10-29

N-cyclopentyl-N-ethylacetamide Chemical and Physical Properties

Names and Identifiers

    • N-cyclopentyl-N-ethylacetamide
    • acetamide, n-cyclopentyl-n-ethyl- (7ci,9ci)
    • SCHEMBL9463026
    • Acetamide,N-cyclopentyl-N-ethyl-
    • Acetamide, N-cyclopentyl-N-ethyl-
    • PLNOBEYYTKAQOO-UHFFFAOYSA-N
    • N-Cyclopentyl-N-ethylacetamide #
    • 54244-76-7
    • Inchi: 1S/C9H17NO/c1-3-10(8(2)11)9-6-4-5-7-9/h9H,3-7H2,1-2H3
    • InChI Key: PLNOBEYYTKAQOO-UHFFFAOYSA-N
    • SMILES: O=C(C)N(CC)C1CCCC1

Computed Properties

  • Exact Mass: 155.131014166g/mol
  • Monoisotopic Mass: 155.131014166g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 139
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 20.3?2

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Additional information on N-cyclopentyl-N-ethylacetamide

Professional Introduction to N-cyclopentyl-N-ethylacetamide (CAS No. 54244-76-7)

N-cyclopentyl-N-ethylacetamide, identified by the chemical compound code CAS No. 54244-76-7, is a significant molecule in the field of pharmaceutical chemistry and has garnered considerable attention due to its unique structural and functional properties. This compound, featuring a cyclopentyl group and an ethyl substituent on an acetamide backbone, exhibits a range of potential applications that span from medicinal chemistry to material science. The detailed exploration of this molecule not only sheds light on its synthetic pathways but also highlights its role in contemporary research and development.

The structural configuration of N-cyclopentyl-N-ethylacetamide is characterized by a highly stable cyclopentane ring fused with an amide functional group, which is further modified by an ethyl chain. This specific arrangement imparts distinct physicochemical properties to the compound, making it a versatile candidate for various biochemical interactions. The cyclopentyl moiety, known for its rigidity and lipophilicity, contributes to the molecule's solubility profile and binding affinity, while the ethyl group enhances its metabolic stability.

In recent years, N-cyclopentyl-N-ethylacetamide has been extensively studied for its pharmacological potential. Researchers have been particularly interested in its role as a modulator of enzymatic activity and as a precursor in the synthesis of more complex pharmacophores. The compound's ability to interact with biological targets has led to investigations into its potential as an anti-inflammatory agent, a neuroprotective compound, and even a candidate for treating neurological disorders such as Alzheimer's disease.

One of the most compelling aspects of N-cyclopentyl-N-ethylacetamide is its synthetic accessibility. The presence of well-defined functional groups allows for facile modifications through various chemical reactions, including acetylation, alkylation, and condensation reactions. These synthetic pathways have enabled chemists to explore derivatives of this compound, each with tailored properties for specific applications. For instance, researchers have synthesized analogs of N-cyclopentyl-N-ethylacetamide that exhibit enhanced binding affinity to certain receptors or improved pharmacokinetic profiles.

The investigation into the biological activity of N-cyclopentyl-N-ethylacetamide has been complemented by computational studies that leverage advanced molecular modeling techniques. These studies have provided valuable insights into the molecule's interactions with biological targets at the atomic level. By simulating these interactions, scientists have been able to predict the efficacy and potential side effects of N-cyclopentyl-N-ethylacetamide-based drugs before they enter clinical trials. This approach has significantly accelerated the drug discovery process and reduced the reliance on empirical screening methods.

Moreover, the environmental impact of synthesizing and utilizing N-cyclopentyl-N-ethylacetamide has been a focal point in recent research. Efforts have been made to develop greener synthetic routes that minimize waste and reduce energy consumption. These initiatives align with broader trends in sustainable chemistry, where the goal is to develop processes that are environmentally friendly without compromising on yield or purity. The adoption of biocatalysis and flow chemistry techniques has been particularly promising in this context.

The commercial significance of N-cyclopentyl-N-ethylacetamide cannot be overstated. Its use as an intermediate in the production of fine chemicals and pharmaceuticals has made it a valuable commodity in industrial settings. Companies specializing in specialty chemicals have integrated this compound into their product portfolios due to its versatility and cost-effectiveness. As demand for high-quality intermediates grows, N-cyclopentyl-N-ethylacetamide is expected to remain a key player in the chemical industry.

Looking ahead, the future research directions for N-cyclopentyl-N-ethylacetamide are multifaceted. Continued exploration into its pharmacological properties will likely uncover new therapeutic applications, while advancements in synthetic chemistry may lead to more efficient production methods. Additionally, interdisciplinary approaches combining organic chemistry with bioinformatics could unlock novel insights into how this compound interacts with biological systems. Such collaborative efforts are essential for driving innovation in the field.

In conclusion, N-cyclopentyl-N-ethylacetamide (CAS No. 54244-76-7) stands as a testament to the ingenuity of modern chemical research. Its unique structure and diverse applications make it a cornerstone in both academic laboratories and industrial settings. As scientists continue to unravel its mysteries, we can anticipate further breakthroughs that will enhance our understanding of this remarkable compound and its potential contributions to medicine and beyond.

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