• 1. Always a matter of interpretation: inferring student knowledge and understanding from research data
  Chem. Educ. Res. Pract., 2017,18, 7-12
• 2. An AuNPs-functionalized AlGaN/GaN high electron mobility transistor sensor for ultrasensitive detection of TNT?
  Ying Li,Weirong Yao,Yunfei Xie,Renjun Pei RSC Adv., 2015,5, 98724-98729
• 3. An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon?
  Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
• 4. Agricultural
  Analyst, 1947,72, 170-172
• 5. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
  Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Imidazoles Substituted imidazoles

Comprehensive Overview of 1H-Imidazole-4,5-dicarbohydrazide (CAS No. 5423-20-1): Properties, Applications, and Innovations

1H-Imidazole-4,5-dicarbohydrazide (CAS No. 5423-20-1) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and materials science research. This imidazole derivative features a unique molecular structure with two carbohydrazide functional groups, making it a versatile intermediate for synthesizing high-value compounds. Its chemical stability and reactivity have positioned it as a key player in drug discovery, polymer chemistry, and agrochemical development.

Recent trends in green chemistry and sustainable synthesis have amplified interest in 1H-Imidazole-4,5-dicarbohydrazide. Researchers are exploring its potential as a biocompatible linker for drug-delivery systems, particularly in cancer therapeutics and antimicrobial agents. The compound's ability to form stable coordination complexes with metal ions also makes it valuable for designing functional materials, such as MOFs (Metal-Organic Frameworks) and corrosion inhibitors.

From an industrial perspective, 1H-Imidazole-4,5-dicarbohydrazide is increasingly used in the production of high-performance polymers. Its dual hydrazide groups enable cross-linking reactions that enhance thermal stability and mechanical strength in polyimide resins—a critical requirement for aerospace and electronics applications. Innovations in 3D printing materials and flexible electronics further underscore its relevance in cutting-edge technologies.

The compound's pharmacological potential is another hot topic. Computational studies suggest that 1H-Imidazole-4,5-dicarbohydrazide derivatives may exhibit enzyme inhibitory activity, particularly against targets like tyrosine kinases and PARP enzymes. These findings align with the growing demand for precision medicine and targeted therapies. Additionally, its role in chemo-sensors for detecting heavy metals resonates with environmental monitoring needs.

Quality control and analytical methods for CAS No. 5423-20-1 are frequently discussed in scientific literature. Techniques like HPLC, NMR spectroscopy, and mass spectrometry are essential for verifying purity, given its applications in sensitive domains. Regulatory compliance, especially for GMP-grade synthesis, remains a priority for manufacturers.

In summary, 1H-Imidazole-4,5-dicarbohydrazide exemplifies the convergence of multidisciplinary research. Its adaptability across drug development, advanced materials, and environmental science ensures its continued relevance. As industries prioritize sustainability and innovation, this compound is poised to play a pivotal role in shaping future technologies.

• 392249-81-9(1H-Imidazo[4,5-d]pyridazine-4,7-dione, 5,6-dihydro-5,6-dimethyl-)
• 23584-99-8(1H-Imidazole-5-carboxylicacid, 2-methylhydrazide)
• 13480-40-5(5H,6H,7H,8H-pyrazino[2,3-d]pyridazine-5,8-dione)
• 110475-22-4(1H-Imidazole-5-carboxylicacid, 2-methyl-, hydrazide)
• 26832-08-6(1H-Imidazole-4-carboxamide)
• 104893-68-7(2-Pyrazinecarboxylicacid, 3-methyl-, hydrazide)
• 18329-78-7(1H-imidazole-4-carbohydrazide)
• 71704-67-1(4-methyl-1H-imidazole-5-carbohydrazide)
• 308305-50-2(1H-Imidazole-5-carboxylicacid, 4-methyl-, 2-(1-methylethylidene)hydrazide)
• 124709-80-4(1H-Imidazole-5-carboxamide,2,4-dimethyl-)