Cas no 54229-31-1 (Diethylene glycol monoformate)

Diethylene glycol monoformate is a versatile chemical ester formed by the reaction of diethylene glycol with formic acid. It is characterized by its clear, colorless appearance and moderate viscosity. The compound exhibits excellent solvency properties, making it useful as a coalescing agent, plasticizer, or intermediate in organic synthesis. Its balanced hydrophilicity and lipophilicity enable effective performance in formulations requiring controlled evaporation rates. The ester's stability under typical storage conditions and compatibility with a range of resins and polymers are notable technical advantages. It finds application in coatings, adhesives, and specialty chemical production where a high-boiling, polar solvent with low toxicity is required.
Diethylene glycol monoformate structure
Diethylene glycol monoformate structure
Product Name:Diethylene glycol monoformate
CAS No:54229-31-1
MF:C5H10O4
MW:134.130502223969
CID:940134
PubChem ID:23448310
Update Time:2025-06-13

Diethylene glycol monoformate Chemical and Physical Properties

Names and Identifiers

    • Diethylene glycol monoformate
    • formic acid,2-(2-hydroxyethoxy)ethanol
    • 2-(2-Hydroxyethoxy)ethyl formate
    • ethanol, 2-[2-(formyloxy)ethoxy]-
    • LogP
    • SCHEMBL1010288
    • 54229-31-1
    • diethylene glycol formate
    • HXRBPRAGWPENTP-UHFFFAOYSA-N
    • DB-250569
    • EN300-6494414
    • Inchi: 1S/C5H10O4/c6-1-2-8-3-4-9-5-7/h5-6H,1-4H2
    • InChI Key: HXRBPRAGWPENTP-UHFFFAOYSA-N
    • SMILES: O(CCO)CCOC=O

Computed Properties

  • Exact Mass: 134.0579
  • Monoisotopic Mass: 134.05790880g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 6
  • Complexity: 64
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.7
  • Topological Polar Surface Area: 55.8?2

Experimental Properties

  • PSA: 55.76

Diethylene glycol monoformate Pricemore >>

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Diethylene glycol monoformate Related Literature

Additional information on Diethylene glycol monoformate

Chemical Profile of Diethylene glycol monoformate (CAS No. 54229-31-1)

Diethylene glycol monoformate (CAS No. 54229-31-1) is a versatile organic compound that has garnered significant attention in the field of chemical and pharmaceutical research due to its unique structural and functional properties. This compound, also known as 2-(2-hydroxyethoxy)ethanol, is a derivative of diethylene glycol and formic acid, and it plays a crucial role in various industrial and scientific applications. Its molecular structure, characterized by the presence of two hydroxyl groups and an ether linkage, makes it a valuable intermediate in the synthesis of polymers, solvents, and pharmaceutical intermediates.

The chemical structure of Diethylene glycol monoformate (CAS No. 54229-31-1) consists of a linear chain with two carbon atoms connected by an ether bond, followed by two hydroxyl groups. This configuration imparts excellent solvency properties, making it an effective solvent for a wide range of organic and inorganic compounds. The compound’s ability to dissolve various substances has led to its extensive use in coatings, adhesives, and as a reaction medium in organic synthesis.

In recent years, Diethylene glycol monoformate (CAS No. 54229-31-1) has been explored for its potential applications in the pharmaceutical industry. Its unique chemical properties make it an attractive candidate for use as a solvent in drug formulation and as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Studies have shown that this compound can enhance the solubility and bioavailability of poorly water-soluble drugs, thereby improving their therapeutic efficacy.

One of the most promising areas of research involving Diethylene glycol monoformate (CAS No. 54229-31-1) is its role in polymer chemistry. The compound’s ability to act as a monomer or co-monomer in polymer synthesis has been investigated extensively. Researchers have found that incorporating Diethylene glycol monoformate (CAS No. 54229-31-1) into polymer chains can improve the mechanical strength, thermal stability, and flexibility of the resulting materials. These properties make it particularly useful in the development of advanced materials for applications such as automotive components, aerospace engineering, and biomedical devices.

Furthermore, the chemical behavior of Diethylene glycol monoformate (CAS No. 54229-31-1) has been studied to understand its reactivity under different conditions. Research has demonstrated that this compound can undergo various chemical reactions, including esterification, etherification, and oxidation, depending on the reaction conditions and catalysts used. These findings have opened up new avenues for the development of novel synthetic routes and processes that utilize Diethylene glycol monoformate (CAS No. 54229-31-1) as a key intermediate.

The environmental impact of Diethylene glycol monoformate (CAS No. 54229-31-1) has also been a subject of interest among researchers. Studies have assessed its biodegradability and toxicity to determine its suitability for industrial applications without posing significant environmental risks. The results have shown that while Diethylene glycol monoformate (CAS No. 54229-31-1) is not highly toxic, its persistence in the environment needs to be monitored carefully to ensure sustainable use.

In conclusion, Diethylene glycol monoformate (CAS No. 54229-31-1) is a multifunctional compound with broad applications across various industries. Its unique chemical properties make it an invaluable solvent and intermediate in pharmaceuticals, polymers, and organic synthesis. As research continues to uncover new uses for this compound, its importance in advancing scientific and industrial technologies is likely to grow further.

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