Cas no 5409-15-4 (4-Chloro-1-hydroxynaphthalene-2-carboxylic acid)
4-Chloro-1-hydroxynaphthalene-2-carboxylic acid Chemical and Physical Properties
Names and Identifiers
-
- 4-Chloro-1-hydroxynaphthalene-2-carboxylic acid
- 4-Chloro-1-hydroxy-2-naphthoic acid
- 2-Naphthalenecarboxylic acid,4-chloro-1-hydroxy
- 2-Naphthoic acid,4-chloro-1-hydroxy
- 4-chloro-1-hydroxy-2-naphthalenecarboxylic acid
- 4-chloro-1-hydroxy-naphthalene-2-carboxylic acid
- 2-Naphthoic acid, 4-chloro-1-hydroxy-
- MFCD00458680
- 2-Naphthalenecarboxylic acid, 4-chloro-1-hydroxy-
- Z367679254
- MLS000063913
- UNII-GE4VW55XKG
- XRWGZDGUXYNIOS-UHFFFAOYSA-
- FT-0711905
- AKOS005173951
- REGID_for_CID_79416
- CHEMBL1325367
- HMS2420N18
- DTXSID10202417
- InChI=1/C11H7ClO3/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,13H,(H,14,15)
- NSC-8472
- Oprea1_109497
- NS00032946
- NSC 8472
- GE4VW55XKG
- LS-04304
- SMR000076783
- NSC8472
- CS-0216442
- EN300-43294
- EINECS 226-477-7
- 5409-15-4
- SR-01000277205
- SR-01000277205-1
- 4-Chloro-1-hydroxy-2-naphthoic acid #
- SCHEMBL485443
- STK363124
- G26079
- DTXCID10124908
- DA-17878
- ALBB-013697
- AE-848/32735016
- 4-CHLORO-1-HYDROXY-2-NAPHTHOICACID
-
- MDL： MFCD00458680
- Inchi： 1S/C11H7ClO3/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,13H,(H,14,15)
- InChI Key： XRWGZDGUXYNIOS-UHFFFAOYSA-N
- SMILES： ClC1C=C(C(=O)O)C(=C2C=CC=CC2=1)O
Computed Properties
- Exact Mass: 222.00800
- Monoisotopic Mass: 222.0083718g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 15
- Rotatable Bond Count: 1
- Complexity: 256
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: nothing
- Topological Polar Surface Area: 57.5?2
Experimental Properties
- PSA: 57.53000
- LogP: 2.89700
4-Chloro-1-hydroxynaphthalene-2-carboxylic acid Customs Data
- HS CODE：2918290000
- Customs Data：
China Customs Code:
2918290000Overview:
2918290000 Other carboxylic acids and anhydrides containing phenolic groups but not other oxy groups\Acyl halide\Peroxides and peroxyacids and their derivatives.Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods).VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Regulatory conditions:
A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goodsInspection and quarantine category:
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported foodSummary:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%
4-Chloro-1-hydroxynaphthalene-2-carboxylic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | C612760-25mg |
4-chloro-1-hydroxynaphthalene-2-carboxylic Acid |
5409-15-4 | 25mg |
$ 50.00 | 2022-06-06 | ||
| TRC | C612760-50mg |
4-chloro-1-hydroxynaphthalene-2-carboxylic Acid |
5409-15-4 | 50mg |
$ 70.00 | 2022-06-06 | ||
| TRC | C612760-250mg |
4-chloro-1-hydroxynaphthalene-2-carboxylic Acid |
5409-15-4 | 250mg |
$ 295.00 | 2022-06-06 | ||
| Chemenu | CM141577-5g |
4-Chloro-1-hydroxy-2-naphthoic acid |
5409-15-4 | 97% | 5g |
$711 | 2021-08-05 | |
| Chemenu | CM141577-5g |
4-Chloro-1-hydroxy-2-naphthoic acid |
5409-15-4 | 97% | 5g |
$*** | 2023-05-30 | |
| abcr | AB408562-500 mg |
4-Chloro-1-hydroxy-2-naphthoic acid |
5409-15-4 | 500MG |
€254.60 | 2023-02-03 | ||
| abcr | AB408562-1 g |
4-Chloro-1-hydroxy-2-naphthoic acid |
5409-15-4 | 1g |
€322.50 | 2023-04-25 | ||
| abcr | AB408562-5 g |
4-Chloro-1-hydroxy-2-naphthoic acid |
5409-15-4 | 5g |
€907.00 | 2023-04-25 | ||
| Enamine | EN300-43294-0.05g |
4-chloro-1-hydroxynaphthalene-2-carboxylic acid |
5409-15-4 | 95.0% | 0.05g |
$66.0 | 2025-03-21 | |
| Enamine | EN300-43294-0.1g |
4-chloro-1-hydroxynaphthalene-2-carboxylic acid |
5409-15-4 | 95.0% | 0.1g |
$98.0 | 2025-03-21 |
4-Chloro-1-hydroxynaphthalene-2-carboxylic acid Suppliers
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Additional information on 4-Chloro-1-hydroxynaphthalene-2-carboxylic acid
Introduction to 4-Chloro-1-Hydroxynaphthalene-2-Carboxylic Acid (CAS No: 5409-15-4)
The compound 4-Chloro-1-Hydroxynaphthalene-2-Carboxylic Acid, with the CAS number 5409-15-4, is a significant organic compound that has garnered attention in various fields of research, particularly in pharmaceuticals and materials science. This compound is characterized by its unique structure, which includes a naphthalene ring system substituted with a hydroxyl group at position 1 and a chlorine atom at position 4, along with a carboxylic acid group at position 2. These functional groups impart the compound with distinctive chemical and biological properties, making it a valuable molecule for further exploration.
Recent studies have highlighted the potential of 4-Chloro-1-Hydroxynaphthalene-2-Carboxylic Acid in drug development, particularly in the context of its ability to interact with specific biological targets. Researchers have explored its role as a potential therapeutic agent in treating various diseases, including cancer and inflammatory disorders. The compound's structure allows for interactions with key enzymes and receptors, which could be harnessed to develop novel drugs with improved efficacy and reduced side effects.
The synthesis of 5409-15-4 involves a multi-step process that typically begins with the preparation of the naphthalene derivative followed by functionalization to introduce the hydroxyl and chlorine substituents. Advanced synthetic techniques, such as Suzuki coupling and Friedel-Crafts acylation, have been employed to achieve high yields and purity. These methods not only ensure the quality of the compound but also pave the way for large-scale production, which is essential for its commercial applications.
In terms of physical and chemical properties, 4-Chloro-1-Hydroxynaphthalene-2-Carboxylic Acid exhibits a melting point of approximately 300°C and is sparingly soluble in water but dissolves readily in organic solvents such as dichloromethane and ethanol. Its UV-vis spectrum reveals strong absorption bands in the visible region, indicating potential applications in optoelectronic materials. Additionally, the compound's stability under various conditions has been thoroughly investigated, making it suitable for use in both laboratory and industrial settings.
The biological activity of this compound has been extensively studied using various assays. In vitro experiments have demonstrated its ability to inhibit key enzymes involved in disease pathways, such as cyclooxygenase (COX) and lipoxygenase (LOX), which are implicated in inflammation and cancer progression. Furthermore, preclinical studies using animal models have shown promising results, with the compound exhibiting anti-inflammatory and anti-proliferative effects without significant toxicity to healthy cells.
Recent advancements in computational chemistry have enabled researchers to predict the binding affinity of 5409-15-4 to various protein targets with high accuracy. Molecular docking studies have revealed that the hydroxyl and carboxylic acid groups play a critical role in stabilizing interactions within protein binding pockets, suggesting potential applications in drug design where precise targeting is essential.
In conclusion, 4-Chloro-1-Hydroxynaphthalene-2-Carboxylic Acid (CAS No: 5409-15-4) is a versatile compound with significant potential across multiple disciplines. Its unique structure, coupled with its promising biological activity and stability under various conditions, positions it as a valuable tool for researchers seeking innovative solutions in drug development and materials science.
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