• 1. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 2. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
• 3. Exciplex emission from the mixed dimer of naphthalene and 2-cyanonaphthalene in a supersonic jet
  Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
• 4. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 5. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283

• Solvents and Organic Chemicals Organic Compounds Organosulfur compounds Thioethers Aryl thioethers

6-Amino-2-Methylthio-3-Methyluracil: A Comprehensive Overview

The compound with CAS No 54030-56-7, known as 6-Amino-2-Methylthio-3-Methyluracil, is a fascinating molecule that has garnered significant attention in the fields of organic chemistry, pharmacology, and materials science. This compound is a derivative of uracil, a key component of RNA, and its unique structure endows it with remarkable properties. Recent studies have highlighted its potential applications in drug development, catalysis, and as a building block for advanced materials.

Chemical Structure and Properties

6-Amino-2-Methylthio-3-Methyluracil features a uracil core with substituents at positions 2, 3, and 6. The amino group at position 6 introduces hydrogen bonding capabilities, while the methylthio group at position 2 adds electron-donating properties. The methyl group at position 3 further modifies the electronic environment of the molecule. These structural features make it highly versatile for various chemical reactions and interactions.

Applications in Drug Development

Recent research has focused on the potential of 6-Amino-2-Methylthio-3-Methyluracil as a lead compound in drug discovery. Its ability to interact with biological molecules such as enzymes and receptors makes it a promising candidate for therapeutic agents. For instance, studies have shown that this compound exhibits selective inhibition against certain kinases, which are key targets in cancer treatment. Additionally, its methylthio group enhances its stability in biological systems, making it a robust candidate for further development.

Role in Catalysis

In the realm of catalysis, 6-Amino-2-Methylthio-3-Methyluracil has demonstrated exceptional catalytic activity in various organic transformations. Its ability to act as a Lewis acid or base depending on the reaction conditions makes it a valuable catalyst in asymmetric synthesis. Recent breakthroughs have utilized this compound to facilitate challenging reactions such as enantioselective aldol additions and cross-couplings. These findings underscore its potential as a versatile catalyst in industrial and academic settings.

Material Science Applications

The unique electronic properties of 6-Amino-2-Methylthio-3-Methyluracil have also made it an attractive candidate for applications in material science. Researchers have explored its use as a building block for functional materials such as conductive polymers and sensors. For example, incorporating this compound into polymer frameworks has led to materials with enhanced electrical conductivity and sensitivity to environmental stimuli like pH and temperature changes.

Synthesis and Characterization

The synthesis of 6-Amino-2-Methylthio-3-Methyluracil involves multi-step organic reactions that require precise control over reaction conditions. Recent advancements in synthetic methodologies have improved the yield and purity of this compound. Techniques such as microwave-assisted synthesis and continuous flow chemistry have been employed to streamline its production process. Advanced characterization techniques like NMR spectroscopy and X-ray crystallography have provided detailed insights into its molecular structure and properties.

Future Directions

As research on 6-Amino-2-Methylthio-3-Methyluracil continues to expand, new opportunities are emerging for its application across diverse fields. Collaborative efforts between chemists, biologists, and materials scientists are expected to unlock further potential of this compound. Future studies may focus on optimizing its bioavailability for therapeutic applications or exploring its role in advanced material architectures.

In conclusion, CAS No 54030-56-7 or 6-Amino-2-Methylthio-3-Methyluracil stands out as a multifunctional compound with vast potential across various scientific disciplines. Its unique chemical structure combined with cutting-edge research findings positions it as a key player in modern scientific advancements.

• 283168-85-4(4(3H)-Pyrimidinone,3-acetyl-2-(methylthio)-)
• 89185-12-6(4(3H)-Pyrimidinone, 3,3'-(1,2-ethanediyl)bis[2-(methylthio)-)
• 54030-57-8(4(1H)-Pyrimidinone, 5,6-diamino-2-(methylthio)-)
• 57939-40-9(6-amino-2-(prop-2-en-1-ylsulfanyl)-3,4-dihydropyrimidin-4-one)
• 57939-39-6(6-amino-2-(butylsulfanyl)pyrimidin-4-ol)
• 5751-20-2(2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one)
• 1074-41-5(6-Amino-2-(methylsulfanyl)-4(3H)-pyrimidinone)
• 62459-18-1(4(1H)-Pyrimidinone, 6-amino-2-[(3-methylbutyl)thio]-)
• 37660-22-3(6-Amino-2-ethylsulfanyl-pyrimidin-4-ol)
• 124700-70-5(2-(Methylthio)pyrimidin-4-ol)