Cas no 53943-88-7 (Letosteine)

Letosteine is a mucolytic agent and antioxidant primarily used in respiratory therapy to manage chronic obstructive pulmonary disease (COPD) and bronchitis. Its mechanism involves breaking disulfide bonds in mucus proteins, reducing viscosity and improving clearance. Additionally, Letosteine exhibits free radical scavenging properties, mitigating oxidative stress in pulmonary tissues. The compound is characterized by its dual-action efficacy, combining mucolytic and anti-inflammatory effects with a favorable safety profile. It is often administered orally or via inhalation, demonstrating good bioavailability and low systemic toxicity. Letosteine’s stability and compatibility with standard respiratory therapies make it a reliable option for long-term management of respiratory conditions.
Letosteine structure
Letosteine structure
Product Name:Letosteine
CAS No:53943-88-7
MF:C10H17NO4S2
MW:279.376280546188
CID:56498
PubChem ID:68707
Update Time:2025-08-02

Letosteine Chemical and Physical Properties

Names and Identifiers

    • Letosteine
    • 2-[2-(2-ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid
    • Letosteina
    • Letosteinum
    • Viscotiol
    • 2-(2-((2-Ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
    • Letosteine (INN)
    • 2-(2-((Carboxymethyl)thio)ethyl)-4-thiazolidinecarboxylic acid 2-ethyl ester
    • Letosteine [INN]
    • 2-{2-[(2-ethoxy-2-oxoethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid
    • Q660090
    • UNII-6MVF9U95DW
    • BCP17027
    • DB08939
    • LETOSTEINE [MART.]
    • HY-107355
    • CS-0028204
    • LETOSTEINE [WHO-DD]
    • 4-Thiazolidinecarboxylic acid, 2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)-
    • AKOS015893059
    • A923520
    • CHEBI:88271
    • LETOSTEINE [MI]
    • CHEMBL2105044
    • BRD-A32597168-001-01-0
    • MFCD00867663
    • KS-5194
    • 6MVF9U95DW
    • EINECS 258-879-3
    • SCHEMBL19562
    • DTXSID70866372
    • D07380
    • H10643
    • MLS006010171
    • Viscotiol (TN)
    • 53943-88-7
    • Letosteinum [INN-Latin]
    • NS00057884
    • SMR004701279
    • Letosteina [INN-Spanish]
    • IKOCLISPVJZJEA-UHFFFAOYSA-N
    • BRD-A32597168-001-03-6
    • LETOSTEINE (MART.)
    • 4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-
    • 2-(2-((2-ethoxy-2-oxoethyl)sulfanyl)ethyl)-1,3-thiazolidine-4-carboxylic acid
    • 4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-; 2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid; Letosteine; Viscotiol; Visoctiol
    • Letosteinum (INN-Latin)
    • DTXCID20814661
    • Letosteina (INN-Spanish)
    • MDL: MFCD00867663
    • Inchi: 1S/C10H17NO4S2/c1-2-15-9(12)6-16-4-3-8-11-7(5-17-8)10(13)14/h7-8,11H,2-6H2,1H3,(H,13,14)
    • InChI Key: IKOCLISPVJZJEA-UHFFFAOYSA-N
    • SMILES: S1CC(C(=O)O)NC1CCSCC(=O)OCC

Computed Properties

  • Exact Mass: 279.06000
  • Monoisotopic Mass: 279.06
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 8
  • Complexity: 275
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 126A^2
  • XLogP3: -1

Experimental Properties

  • Color/Form: White crystalline powder
  • Density: 1.3±0.1 g/cm3
  • Melting Point: 136-140°C
  • Boiling Point: 470.0±45.0 °C at 760 mmHg
  • Flash Point: 238.1±28.7 °C
  • Refractive Index: 1.547
  • PSA: 126.23000
  • LogP: 1.11730
  • Vapor Pressure: 0.0±2.5 mmHg at 25°C

Letosteine Customs Data

  • HS CODE:2934999090
  • Customs Data:

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Letosteine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM189486-5g
2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
53943-88-7 97%
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$644 2021-08-05
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$ 58.00 2023-09-07
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$115.00 2023-05-18
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$253.00 2023-05-18
Chemenu
CM189486-250mg
2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
53943-88-7 97%
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Chemenu
CM189486-1g
2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
53943-88-7 97%
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Chemenu
CM189486-5g
2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
53943-88-7 97%
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$*** 2023-05-30
Crysdot LLC
CD11108417-5g
2-(2-((2-Ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
53943-88-7 97%
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$682 2024-07-19
eNovation Chemicals LLC
Y1249985-10mg
4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-
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Additional information on Letosteine

Letosteine: A Comprehensive Overview

Letosteine, also known by its CAS registry number CAS No. 53943-88-7, is a compound that has garnered significant attention in recent years due to its unique properties and potential applications. This compound is a derivative of cysteine, a naturally occurring amino acid, and has been extensively studied for its role in various biochemical processes. The structure of Letosteine includes a sulfur-containing side chain, which contributes to its ability to act as a precursor for glutathione, a critical antioxidant in the human body.

Recent studies have highlighted the importance of Letosteine in maintaining cellular health and protecting against oxidative stress. Oxidative stress is a condition characterized by an imbalance between free radicals and antioxidants in the body, leading to cellular damage and various diseases. By serving as a precursor for glutathione, Letosteine plays a pivotal role in neutralizing free radicals and safeguarding cellular components from oxidative damage. This makes it a promising candidate for applications in nutraceuticals, cosmetics, and pharmaceuticals.

The synthesis of Letosteine involves several steps, including the isolation of cysteine from biological sources or its chemical synthesis. Advanced techniques such as enzymatic catalysis and fermentation processes have been explored to optimize the production of this compound. Researchers have also investigated the use of recombinant bacteria to enhance the yield of Letosteine, making it more accessible for large-scale production.

In terms of applications, Letosteine has found its way into various industries. In the nutraceutical sector, it is often included in dietary supplements aimed at improving antioxidant defense and overall health. Its ability to enhance glutathione levels makes it particularly valuable for individuals with compromised immune systems or those exposed to environmental toxins. In cosmetics, Letosteine-based products are marketed for their anti-aging properties, as they help protect the skin from oxidative damage caused by UV radiation and pollution.

The pharmaceutical industry has also shown interest in Letosteine, particularly in the development of therapies targeting chronic diseases associated with oxidative stress. For instance, studies have explored its potential in mitigating neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. Preclinical trials have demonstrated that administration of Letosteine can reduce oxidative stress markers and improve cognitive function in animal models.

Beyond its direct applications, research into CAS No. 53943-88-7 has led to insights into its metabolic pathways and interactions with other biomolecules. Scientists have identified key enzymes involved in the conversion of Letosteine strong>

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