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  Ghazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
• 2. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
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• 3. Feasibility of polyethylene composites reinforced by distillers dried fibers with solubles (DDFS) after different generations of ethanol fermentation?
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Comprehensive Guide to 1-4-(prop-1-en-2-yl)phenylethan-1-one (CAS No. 5359-04-6): Properties, Applications, and Market Insights

1-4-(prop-1-en-2-yl)phenylethan-1-one (CAS No. 5359-04-6) is a specialized organic compound with a unique molecular structure that makes it valuable in various industrial and research applications. This aromatic ketone, featuring a propenylphenyl backbone, has garnered attention due to its versatile reactivity and potential uses in flavor and fragrance formulations, pharmaceutical intermediates, and organic synthesis. As sustainability and green chemistry become hot topics in the chemical industry, compounds like 1-4-(prop-1-en-2-yl)phenylethan-1-one are being reevaluated for their eco-friendly potential.

The chemical structure of 1-4-(prop-1-en-2-yl)phenylethan-1-one combines an aromatic ring with both carbonyl and alkenyl functional groups, giving it distinctive physical and chemical properties. With a molecular formula of C11H12O, this compound typically appears as a colorless to pale yellow liquid at room temperature, with moderate solubility in common organic solvents. Researchers are particularly interested in its conjugated system, which contributes to its UV absorption characteristics - a property that makes it potentially useful in photochemical applications and material science.

In the flavor and fragrance industry, 1-4-(prop-1-en-2-yl)phenylethan-1-one has shown promise as a building block for creating novel aromatic compounds. Its molecular framework resembles certain natural plant-derived aromatics, making it a candidate for synthetic essential oil components. As consumers increasingly demand natural-identical fragrances and sustainable scent solutions, this compound's role in green chemistry applications is being actively explored. Recent studies have investigated its potential as a precursor for biodegradable fragrance molecules that meet stringent environmental regulations.

The pharmaceutical sector has shown growing interest in 1-4-(prop-1-en-2-yl)phenylethan-1-one as a potential intermediate for drug synthesis. Its unique structure offers opportunities for creating novel therapeutic compounds, particularly in the development of anti-inflammatory agents and central nervous system drugs. Researchers are examining its potential as a scaffold for targeted drug delivery systems, especially in light of current trends toward personalized medicine and precision pharmaceuticals. The compound's structure-activity relationship is being studied to optimize its pharmacological properties.

From a synthetic chemistry perspective, 1-4-(prop-1-en-2-yl)phenylethan-1-one serves as a valuable building block for organic synthesis. Its reactive functional groups allow for various chemical transformations, including condensation reactions, nucleophilic additions, and cyclization processes. These characteristics make it particularly useful in the development of heterocyclic compounds, which are crucial in many areas of medicinal chemistry and material science. Recent advances in catalytic processes have improved the efficiency of reactions involving this compound, aligning with the industry's push toward atom-economical synthesis.

The market for 1-4-(prop-1-en-2-yl)phenylethan-1-one has shown steady growth, driven by increasing demand from specialty chemical manufacturers and research institutions. Current market analysis indicates particular interest from the Asia-Pacific region, where growing pharmaceutical and fragrance industries are creating new opportunities. Suppliers are focusing on improving production scalability and purity standards to meet the evolving needs of industrial and academic users. The compound's pricing trends reflect its status as a specialty intermediate, with costs influenced by raw material availability and synthetic route efficiency.

Quality control and analytical characterization of 1-4-(prop-1-en-2-yl)phenylethan-1-one typically involve advanced techniques such as gas chromatography (GC), high-performance liquid chromatography (HPLC), and spectroscopic methods including NMR and mass spectrometry. These analytical protocols ensure the compound meets the stringent purity requirements for pharmaceutical-grade materials and high-end fragrance applications. Recent advancements in analytical chemistry have enabled more precise detection of structural isomers and trace impurities, further enhancing quality assurance processes.

Storage and handling of 1-4-(prop-1-en-2-yl)phenylethan-1-one require standard chemical safety precautions. The compound should be kept in airtight containers away from direct sunlight and heat sources to maintain stability. While not classified as hazardous under normal conditions, proper laboratory ventilation and personal protective equipment are recommended when working with this material. These handling protocols align with current laboratory safety standards and chemical management best practices that emphasize risk minimization in research and industrial settings.

Future research directions for 1-4-(prop-1-en-2-yl)phenylethan-1-one include exploring its potential in advanced material applications and catalysis. Scientists are investigating its use in organic electronics due to its conjugated π-system, which could contribute to developing next-generation semiconductors. Additionally, its role in asymmetric synthesis and chiral chemistry is being examined, particularly in the context of enantioselective catalysis - a hot topic in modern synthetic methodology development.

For researchers and industry professionals seeking high-purity 1-4-(prop-1-en-2-yl)phenylethan-1-one, it's essential to source the compound from reputable chemical suppliers who provide comprehensive analytical certificates and technical data sheets. The growing emphasis on supply chain transparency and material traceability in the chemical industry makes proper documentation increasingly important. Many suppliers now offer custom synthesis services and scale-up capabilities for this compound, catering to the diverse needs of academic researchers and industrial users alike.

• 389582-37-0(Benzaldehyde, 4-(1-phenylethenyl)-)
• 123926-80-7(Benzaldehyde,3-(1-methylethenyl)-)
• 87324-13-8(Ethanone, 1-[4-(1-phenylethenyl)phenyl]-)
• 63444-57-5(Methanone, (3-ethenylphenyl)phenyl-)
• 10537-63-0(1-(4-Ethenylphenyl)ethan-1-one)
• 87771-42-4(Ethanone,1-[3-(1-methylethenyl)phenyl]-)
• 619326-94-2(Ethanone, 1-[4-(2-phenyl-2-propenyl)phenyl]-)
• 3139-85-3(Methanone, (4-ethenylphenyl)phenyl-)
• 64217-99-8(Ethanone,1-(3-ethenylphenyl)-)
• 10133-50-3(4-(prop-1-en-2-yl)benzaldehyde)