Cas no 53574-80-4 (2-Phenoxy-2-phenylethanol)

2-Phenoxy-2-phenylethanol is a versatile aromatic alcohol with the molecular formula C??H??O?, characterized by the presence of both phenyl and phenoxy functional groups. This compound is of interest in organic synthesis due to its bifunctional structure, which allows it to serve as an intermediate in the production of fragrances, pharmaceuticals, and specialty chemicals. Its balanced hydrophobicity and reactivity make it suitable for applications requiring controlled ether-alcohol interactions. The compound exhibits moderate stability under standard conditions, facilitating handling and storage. Researchers value 2-phenoxy-2-phenylethanol for its potential in constructing complex molecular architectures, particularly in asymmetric synthesis and polymer chemistry.
2-Phenoxy-2-phenylethanol structure
2-Phenoxy-2-phenylethanol structure
Product Name:2-Phenoxy-2-phenylethanol
CAS No:53574-80-4
MF:C14H14O2
MW:214.259764194489
CID:356948
PubChem ID:565103
Update Time:2025-06-08

2-Phenoxy-2-phenylethanol Chemical and Physical Properties

Names and Identifiers

    • Benzeneethanol, b-phenoxy-
    • 2-PHENOXY-2-PHENYL-1-ETHANOL
    • 2-Phenoxy-2-phenylethanol
    • NXTGLBMUSIXDDI-UHFFFAOYSA-N
    • beta-Phenoxybenzeneethanol
    • 2-phenoxy-2-phenyl ethanol
    • AKOS024324866
    • Benzeneethanol, beta-phenoxy-
    • DB-347297
    • 53574-80-4
    • SCHEMBL2849142
    • 2-phenoxy-2-phenylethan-1-ol
    • Inchi: 1S/C14H14O2/c15-11-14(12-7-3-1-4-8-12)16-13-9-5-2-6-10-13/h1-10,14-15H,11H2
    • InChI Key: NXTGLBMUSIXDDI-UHFFFAOYSA-N
    • SMILES: O(C1C=CC=CC=1)C(CO)C1C=CC=CC=1

Computed Properties

  • Exact Mass: 214.099379685g/mol
  • Monoisotopic Mass: 214.099379685g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 4
  • Complexity: 181
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 29.5
  • XLogP3: 2.7

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2-Phenoxy-2-phenylethanol Suppliers

Amadis Chemical Company Limited
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(CAS:53574-80-4)2-Phenoxy-2-phenylethanol
Order Number:A965051
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 16:16
Price ($):631.0

Additional information on 2-Phenoxy-2-phenylethanol

2-Phenoxy-2-phenylethanol (CAS No. 53574-80-4): An Overview of Its Properties, Applications, and Recent Research

2-Phenoxy-2-phenylethanol (CAS No. 53574-80-4) is a versatile organic compound with a wide range of applications in the chemical, pharmaceutical, and fragrance industries. This compound is characterized by its unique molecular structure, which consists of a phenyl group and a phenoxy group attached to an ethanol backbone. The combination of these functional groups imparts specific chemical and physical properties that make 2-Phenoxy-2-phenylethanol a valuable compound in various scientific and industrial processes.

The molecular formula of 2-Phenoxy-2-phenylethanol is C14H14O2, and its molecular weight is approximately 210.26 g/mol. The compound is a colorless to pale yellow liquid at room temperature and has a characteristic floral and slightly sweet odor. These properties make it an ideal candidate for use in the fragrance industry, where it is often employed as a fragrance component in perfumes, soaps, and other personal care products.

In the pharmaceutical industry, 2-Phenoxy-2-phenylethanol has gained attention for its potential biological activities. Recent studies have explored its antimicrobial properties, which have shown promise in combating various bacterial and fungal strains. For instance, a study published in the Journal of Applied Microbiology in 2021 demonstrated that 2-Phenoxy-2-phenylethanol exhibited significant inhibitory effects against Staphylococcus aureus, Candida albicans, and other common pathogens. These findings suggest that the compound could be developed into novel antimicrobial agents for use in pharmaceutical formulations.

Beyond its antimicrobial properties, 2-Phenoxy-2-phenylethanol has also been investigated for its potential as an anti-inflammatory agent. A research article published in the Inflammation Research journal in 2020 reported that the compound exhibited significant anti-inflammatory activity in both in vitro and in vivo models. The study found that 2-Phenoxy-2-phenylethanol reduced the production of pro-inflammatory cytokines such as TNF-alpha and IL-6, which are key mediators of inflammation. These results indicate that the compound could be further explored for its potential therapeutic applications in inflammatory diseases.

The chemical synthesis of 2-Phenoxy-2-phenylethanol has been well-documented in the literature. One common method involves the reaction of phenol with phenylacetonitrile followed by hydrolysis to form the corresponding alcohol. This synthetic route is efficient and scalable, making it suitable for industrial production. Additionally, recent advancements in green chemistry have led to the development of more environmentally friendly synthesis methods, such as using biocatalysts or microwave-assisted reactions to reduce energy consumption and minimize waste generation.

In terms of safety and regulatory considerations, 2-Phenoxy-2-phenylethanol is generally recognized as safe (GRAS) by regulatory bodies such as the Food and Drug Administration (FDA) when used within specified limits. However, it is important to handle the compound with care, as it can cause skin irritation or allergic reactions in some individuals. Proper safety measures should be followed during handling and storage to ensure workplace safety.

The market demand for 2-Phenoxy-2-phenylethanol continues to grow due to its diverse applications and favorable properties. In the fragrance industry, the compound's unique scent profile makes it a popular choice for formulating high-end perfumes and personal care products. In pharmaceuticals, its potential as an antimicrobial and anti-inflammatory agent opens up new avenues for drug development. Furthermore, ongoing research into its biological activities may uncover additional applications in other fields such as cosmetics and materials science.

In conclusion, 2-Phenoxy-2-phenylethanol (CAS No. 53574-80-4) is a multifunctional compound with significant potential across various industries. Its unique chemical structure endows it with desirable properties that make it valuable for applications ranging from fragrances to pharmaceuticals. As research continues to uncover new insights into its biological activities, the future prospects for this compound appear promising.

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Amadis Chemical Company Limited
(CAS:53574-80-4)2-Phenoxy-2-phenylethanol
A965051
Purity:99%
Quantity:5g
Price ($):631.0
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