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• Solvents and Organic Chemicals Organic Compounds Organohalogen compounds Organobromides Organobromides
• Solvents and Organic Chemicals Organic Compounds Organohalogen compounds Organobromides
• Solvents and Organic Chemicals Organic Compounds Organic Halides

Comprehensive Guide to (S)-(+)-1-Bromo-2-methylbutane (CAS No. 534-00-9): Properties, Applications, and Market Insights

(S)-(+)-1-Bromo-2-methylbutane (CAS No. 534-00-9) is a chiral organic compound widely used in pharmaceutical synthesis, agrochemical research, and specialty chemical manufacturing. This optically active alkyl bromide is valued for its role as a building block in asymmetric synthesis, particularly in the production of enantiomerically pure compounds. The (S)-(+)-1-Bromo-2-methylbutane structure features a bromine atom at the primary carbon position and a methyl group at the secondary carbon, creating a versatile intermediate for nucleophilic substitution reactions.

The global demand for chiral building blocks like (S)-(+)-1-Bromo-2-methylbutane has surged in recent years, driven by the pharmaceutical industry's need for enantioselective synthesis. Researchers frequently search for "CAS 534-00-9 applications" or "where to buy (S)-(+)-1-Bromo-2-methylbutane" as this compound gains importance in drug development pipelines. Its high optical purity (typically >98% ee) makes it particularly valuable for creating biologically active molecules with specific stereochemical requirements.

From a chemical perspective, (S)-(+)-1-Bromo-2-methylbutane properties include a molecular weight of 151.04 g/mol, boiling point of approximately 120-122°C, and density of 1.22 g/mL at 25°C. The compound's chiral center at C-2 allows it to serve as a key precursor in the synthesis of various natural products and pharmaceutical intermediates. Recent publications highlight its use in creating flavor and fragrance compounds, as well as in the development of novel catalytic asymmetric reactions.

In the laboratory setting, proper handling of (S)-(+)-1-Bromo-2-methylbutane requires standard organic chemistry safety protocols. While not classified as hazardous under normal conditions, users often search for "534-00-9 safety data" and "storage conditions for chiral bromoalkanes". The compound should be stored in cool, dry conditions away from strong oxidizing agents to maintain its stability and optical purity over time.

The synthesis of (S)-(+)-1-Bromo-2-methylbutane typically involves the optical resolution of racemic mixtures or asymmetric synthesis from chiral pool starting materials. Process chemists frequently investigate "green chemistry approaches to 534-00-9" and "cost-effective production of enantiopure bromoalkanes". Recent advances in biocatalysis and flow chemistry have shown promise for more sustainable production methods of this valuable chiral intermediate.

Market analysis indicates growing interest in (S)-(+)-1-Bromo-2-methylbutane suppliers across North America, Europe, and Asia-Pacific regions. Pharmaceutical companies and contract research organizations are the primary consumers, searching for terms like "high purity CAS 534-00-9" and "bulk quantities of chiral bromo compounds". The compound's price fluctuates based on optical purity levels (typically 97-99%) and order quantities, with current market prices ranging from $50-$200 per gram depending on specifications.

Quality control for (S)-(+)-1-Bromo-2-methylbutane involves rigorous analytical techniques including chiral HPLC, GC-MS, and NMR spectroscopy. Researchers often look for "analytical methods for 534-00-9" and "how to determine enantiomeric excess of bromoalkanes". The compound's characteristic 1H NMR spectrum shows distinct signals for the methyl groups (0.8-1.0 ppm), methylene protons (1.2-1.8 ppm), and the methine proton adjacent to the bromine (4.0-4.2 ppm).

Emerging applications for (S)-(+)-1-Bromo-2-methylbutane include its use in materials science for the synthesis of chiral liquid crystals and in nanotechnology for surface functionalization. The compound's versatility continues to attract research attention, as evidenced by increasing publications containing the keywords "chiral alkylating agents" and "stereoselective synthesis using 534-00-9". These developments position this chiral building block as an important tool in modern organic synthesis.

For researchers working with (S)-(+)-1-Bromo-2-methylbutane, proper documentation of experimental procedures is essential. Common search queries include "reaction conditions with CAS 534-00-9" and "workup procedures for bromoalkane reactions". The compound typically reacts with various nucleophiles under mild conditions, making it suitable for diverse synthetic transformations while maintaining stereochemical integrity.

The future outlook for (S)-(+)-1-Bromo-2-methylbutane appears promising, with anticipated growth in demand from the pharmaceutical and specialty chemicals sectors. Industry analysts predict increased interest in "sustainable chiral intermediates" and "cost-effective routes to 534-00-9" as manufacturers seek to balance economic and environmental considerations. This trend aligns with broader movements toward green chemistry and atom-efficient synthetic methodologies in fine chemical production.

• 15019-28-0(Butane, 1-bromo-2,3-dimethyl-, (R)-)
• 54462-66-7(1,4-dibromo-2-methylbutane)
• 15164-29-1((S)-1-Bromo-2,3-dimethylbutane)
• 59634-99-0(Butane, 1,4-dibromo-2,3-dimethyl-, (2R,3R)-rel-)
• 10422-35-2(1-Bromo-2-methylbutane)
• 40491-78-9(1-bromo-2,2,3,3-tetramethylbutane)
• 30540-31-9(Butane, 1-bromo-2,3-dimethyl-)
• 54462-70-3(1,4-Dibromo-2,3-dimethylbutane)
• 5973-11-5(1-Bromo-2-methylbutane)
• 99032-67-4((2r)-1-bromo-2-methylbutane)