Cas no 53358-21-7 (2-Pentenedioic acid,2-methyl-, (E)- (9CI))

2-Pentenedioic acid, 2-methyl-, (E)- (9CI) is a methyl-substituted unsaturated dicarboxylic acid with a trans (E) configuration. This compound is of interest in organic synthesis and industrial applications due to its reactive diacid structure and conjugated double bond, which facilitate participation in polymerization, esterification, and other addition reactions. The methyl group at the 2-position introduces steric and electronic effects that can influence reactivity and selectivity in chemical transformations. Its well-defined stereochemistry (E-configuration) ensures consistent performance in asymmetric synthesis and material science applications. The compound is typically utilized as an intermediate in pharmaceuticals, specialty polymers, and fine chemicals, where its structural features enable precise molecular design.
2-Pentenedioic acid,2-methyl-, (E)- (9CI) structure
53358-21-7 structure
Product Name:2-Pentenedioic acid,2-methyl-, (E)- (9CI)
CAS No:53358-21-7
MF:C6H8O4
MW:144.125322341919
CID:376880
PubChem ID:6368126
Update Time:2025-05-22

2-Pentenedioic acid,2-methyl-, (E)- (9CI) Chemical and Physical Properties

Names and Identifiers

    • 2-Pentenedioic acid,2-methyl-, (E)- (9CI)
    • (E)-2-methyl-2-Pentenedioic acid
    • 2-methyl-2-pentenedioic acid
    • 2-methylpent-2-enedioic acid
    • (2E)-2-Methyl-2-pentenedioic acid
    • trans-2-Methylglutaconic acid
    • 2-methyl-2E-pentenedioic acid
    • 2E-methyl-glutaconic acid
    • CHEBI:165425
    • 2-Methylglutaconic acid
    • (E)-2-Methylglutaconate
    • AKOS006375405
    • 1-Methyl-1-propene-1,3-dicarboxylic acid
    • LMFA01170079
    • starbld0008162
    • 2-Pentenedioic acid, 2-methyl-, (E)-
    • 53358-21-7
    • 2_methylglutaconic_acid
    • (E)-2-methyl-2-Pentenedioate
    • DTXSID601009869
    • trans-2-Methylglutaconate
    • (E)-2-Methylglutaconic acid
    • (E)-2-methylpent-2-enedioic acid
    • Inchi: 1S/C6H8O4/c1-4(6(9)10)2-3-5(7)8/h2H,3H2,1H3,(H,7,8)(H,9,10)/b4-2+
    • InChI Key: JKGHDBJDBRBRNA-DUXPYHPUSA-N
    • SMILES: OC(C/C=C(/C(=O)O)\C)=O

Computed Properties

  • Exact Mass: 144.04224
  • Monoisotopic Mass: 144.042259
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 3
  • Complexity: 180
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 74.6

Experimental Properties

  • Density: 1.307
  • Melting Point: 141-147?°C
  • Boiling Point: 399.4°Cat760mmHg
  • Flash Point: 209.5°C
  • Refractive Index: 1.508
  • PSA: 74.6

2-Pentenedioic acid,2-methyl-, (E)- (9CI) Security Information

  • Hazardous Material transportation number:NONH for all modes of transport
  • Storage Condition:2-8°C

2-Pentenedioic acid,2-methyl-, (E)- (9CI) Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
XI GE MA AO DE LI QI ( SHANG HAI ) MAO YI Co., Ltd.
74626-10MG
(E)-2-Methylglutaconic acid
53358-21-7 ≥98.0% (HPLC)
10MG
¥767.34 2022-02-23
XI GE MA AO DE LI QI ( SHANG HAI ) MAO YI Co., Ltd.
74626-50MG
(E)-2-Methylglutaconic acid
53358-21-7 ≥98.0% (HPLC)
50MG
¥2689.71 2022-02-23

Additional information on 2-Pentenedioic acid,2-methyl-, (E)- (9CI)

Comprehensive Overview of 2-Pentenedioic acid, 2-methyl-, (E)- (9CI) (CAS No. 53358-21-7)

2-Pentenedioic acid, 2-methyl-, (E)- (9CI), with the CAS number 53358-21-7, is a specialized organic compound that has garnered attention in various industrial and research applications. This unsaturated dicarboxylic acid, characterized by its (E)-configuration and a methyl substituent at the second carbon, plays a significant role in synthetic chemistry, material science, and even biotechnology. Its unique structure makes it a valuable intermediate in the synthesis of polymers, pharmaceuticals, and agrochemicals. Researchers and manufacturers are increasingly exploring its potential due to its reactivity and versatility.

The compound's IUPAC name and CAS registry number are critical identifiers for professionals seeking precise chemical data. In recent years, the demand for sustainable and bio-based chemicals has surged, aligning with global trends toward green chemistry. 2-Pentenedioic acid, 2-methyl-, (E)- (9CI) fits into this narrative as a candidate for eco-friendly synthesis routes. Its potential applications in biodegradable polymers and renewable materials have sparked interest among scientists and engineers aiming to reduce environmental impact.

One of the most searched questions related to this compound is: "What are the industrial uses of 2-Pentenedioic acid derivatives?" The answer lies in its role as a building block for high-performance polymers and specialty coatings. For instance, its incorporation into polyesters and polyamides can enhance thermal stability and mechanical properties. Additionally, its unsaturated backbone allows for further functionalization, making it a favorite in click chemistry and cross-linking reactions.

Another hot topic is the compound's relevance in pharmaceutical research. While not a drug itself, 2-Pentenedioic acid, 2-methyl-, (E)- (9CI) serves as a precursor for active pharmaceutical ingredients (APIs). Its structure is amenable to modifications that can yield bioactive molecules with potential therapeutic effects. This aligns with the growing focus on drug discovery and personalized medicine, where tailored chemical intermediates are in high demand.

From an analytical perspective, the compound's spectroscopic properties (e.g., NMR, IR, and MS data) are well-documented, aiding in its identification and quality control. Laboratories often seek reference standards of CAS 53358-21-7 for calibration and method validation. The rise of AI-driven chemical analysis tools has further streamlined its characterization, enabling faster and more accurate results.

In the context of market trends, the supply chain for 2-Pentenedioic acid derivatives is evolving. Companies are investing in scalable production methods, such as catalytic processes and fermentation technologies, to meet the growing demand. This shift reflects broader industry movements toward cost-effective and sustainable manufacturing practices.

To summarize, 2-Pentenedioic acid, 2-methyl-, (E)- (9CI) (CAS No. 53358-21-7) is a multifaceted compound with applications spanning materials science, pharmaceuticals, and green chemistry. Its significance is underscored by its adaptability and the ongoing research into its potential. As industries continue to prioritize innovation and sustainability, this compound is poised to remain a key player in advanced chemical synthesis.

Recommended suppliers
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Hunan Well Medicine Synthesis Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hunan Well Medicine Synthesis Technology Co., Ltd.
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.