Cas no 53163-97-6 (2-Ethoxy-6-methylpyrazine)

2-Ethoxy-6-methylpyrazine is a pyrazine derivative characterized by its ethoxy and methyl substituents, which impart distinct aromatic properties. This compound is primarily utilized as a flavor and fragrance intermediate due to its potent, nutty, and roasted odor profile, often employed in food and beverage applications to enhance savory notes. Its high stability and low volatility make it suitable for use in thermally processed products. The compound's well-defined structure ensures consistent performance in formulations, while its synthetic purity allows for precise control in flavor and fragrance compositions. Its versatility and reliable sensory characteristics make it a valuable component in industrial and research settings.
2-Ethoxy-6-methylpyrazine structure
2-Ethoxy-6-methylpyrazine structure
Product Name:2-Ethoxy-6-methylpyrazine
CAS No:53163-97-6
MF:C7H10N2O
MW:138.167101383209
CID:373026
PubChem ID:104421
Update Time:2025-06-22

2-Ethoxy-6-methylpyrazine Chemical and Physical Properties

Names and Identifiers

    • 2-Ethoxy-6-methylpyrazine
    • Pyrazine,2-ethoxy-6-methyl-
    • 2-ethoxy-6-methyl-pyrazine
    • 2-METHYL-6-ETHOXYPYRAZINE
    • Pyrazine,2-ethoxy-6-methyl
    • Pyrazine,6-ethoxy-2-methyl
    • Pyrazine, 2-ethoxy-6-methyl-
    • Pyrazine, 6-ethoxy-2-methyl
    • D47RK4A68R
    • XBLZVFYOCZVABA-UHFFFAOYSA-N
    • 7536AB
    • FCH857694
    • 2-Ethoxy-6-methylpyrazine, AldrichCPR
    • AK112910
    • AX8021255
    • A829420
    • UNII-D47RK4A68R
    • NS00032666
    • FEMA NO. 3569, -6-ETHOXY
    • DTXSID8068832
    • SCHEMBL2214251
    • 53163-97-6
    • CS-0186630
    • DS-6061
    • W-105766
    • AKOS006285944
    • EINECS 258-402-9
    • Q27276081
    • C75488
    • CHEBI:193650
    • Inchi: 1S/C7H10N2O/c1-3-10-7-5-8-4-6(2)9-7/h4-5H,3H2,1-2H3
    • InChI Key: XBLZVFYOCZVABA-UHFFFAOYSA-N
    • SMILES: O(C1C=NC=C(C)N=1)CC

Computed Properties

  • Exact Mass: 138.07900
  • Monoisotopic Mass: 138.079312947g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 97.6
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.8
  • Topological Polar Surface Area: 35
  • Surface Charge: 0
  • Tautomer Count: nothing

Experimental Properties

  • PSA: 35.01000
  • LogP: 1.18370

2-Ethoxy-6-methylpyrazine Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-Ethoxy-6-methylpyrazine Pricemore >>

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Additional information on 2-Ethoxy-6-methylpyrazine

2-Ethoxy-6-Methylpyrazine: A Comprehensive Overview

2-Ethoxy-6-Methylpyrazine (CAS No. 53163-97-6) is a versatile organic compound that has garnered significant attention in various fields, including chemistry, pharmacology, and materials science. This compound belongs to the pyrazine family, a class of heterocyclic aromatic compounds with two nitrogen atoms in the six-membered ring. The presence of an ethoxy group at position 2 and a methyl group at position 6 imparts unique chemical and physical properties to 2-Ethoxy-6-Methylpyrazine, making it a valuable molecule for both academic research and industrial applications.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of 2-Ethoxy-6-Methylpyrazine through various routes. One of the most promising methods involves the condensation of aldehydes with amines under specific reaction conditions. This approach not only enhances the yield but also ensures high purity, which is critical for downstream applications. Researchers have also explored the use of microwave-assisted synthesis, which significantly reduces reaction time while maintaining product quality.

The structural uniqueness of 2-Ethoxy-6-Methylpyrazine lies in its ability to act as a building block for more complex molecules. For instance, it serves as an intermediate in the synthesis of pyrazine derivatives with potential pharmacological activities. Recent studies have highlighted its role in drug design, particularly in the development of anti-inflammatory and anti-cancer agents. The compound's ability to form hydrogen bonds and its aromaticity make it an ideal candidate for molecular recognition studies.

In the realm of materials science, 2-Ethoxy-6-Methylpyrazine has been investigated for its potential as a precursor in the synthesis of conductive polymers. These polymers exhibit excellent electrical properties and are being explored for use in flexible electronics and energy storage devices. The compound's ability to undergo polymerization under mild conditions has further cemented its importance in this field.

From an environmental perspective, 2-Ethoxy-6-Methylpyrazine has shown promise as a biodegradable additive in agricultural applications. Its ability to enhance soil fertility without leaving harmful residues aligns with global efforts to promote sustainable agriculture. Recent field trials have demonstrated its effectiveness in improving crop yields while maintaining soil health.

The growing interest in 2-Ethoxy-6-Methylpyrazine can also be attributed to its role in flavor chemistry. The compound contributes to the characteristic aroma of certain food products, making it a valuable ingredient in the food industry. Its application as a flavor enhancer is supported by extensive sensory analysis studies, which have confirmed its positive impact on taste perception.

In conclusion, 2-Ethoxy-6-Methylpyrazine (CAS No. 53163-97-6) is a multifaceted compound with applications spanning diverse domains. Its chemical versatility, combined with recent advancements in synthesis and application techniques, positions it as a key molecule for future innovations. As research continues to uncover new potentials, 2-Ethoxy-6-Methylpyrazine is poised to play an increasingly significant role in both academic and industrial settings.

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