Cas no 53088-69-0 (Methyl 2-(m-tolyl)acetate)

Methyl 2-(m-tolyl)acetate is an organic ester compound characterized by its aromatic methyl-substituted phenyl group and acetate functionality. This compound is commonly employed as an intermediate in organic synthesis, particularly in the production of pharmaceuticals, fragrances, and specialty chemicals. Its structure offers versatility in further functionalization, enabling applications in fine chemical manufacturing. The meta-tolyl group enhances stability while maintaining reactivity for selective transformations. The ester group provides a handle for hydrolysis or transesterification, facilitating downstream modifications. With a well-defined molecular weight (178.23 g/mol) and purity, it is suitable for precise synthetic applications. Proper handling under standard laboratory conditions is recommended due to its organic solvent compatibility and moderate reactivity.
Methyl 2-(m-tolyl)acetate structure
Methyl 2-(m-tolyl)acetate structure
Product Name:Methyl 2-(m-tolyl)acetate
CAS No:53088-69-0
MF:C10H12O2
MW:164.201083183289
MDL:MFCD00968468
CID:937924
PubChem ID:5135288
Update Time:2025-11-07

Methyl 2-(m-tolyl)acetate Chemical and Physical Properties

Names and Identifiers

    • Methyl 2-(m-tolyl)acetate
    • methyl 2-(3-methylphenyl)acetate
    • Methyl 3-methylphenylacetate
    • Methyl m-tolylacetate
    • methyl 2-m-tolylacetate
    • 3-Methylphenylacetic acid methyl ester
    • Benzeneacetic acid, 3-methyl-, methyl ester
    • m-tolylacetic acid methyl ester
    • m-toly-acetic acid methyl ester
    • m-tolyl-acetic acid methyl ester
    • AWTKFTNNPQGGLX-UHFFFAOYSA-N
    • methyl 2-(3-methylphenyl)ethanoate
    • 7522AB
    • 2-(3-m
    • Q63391953
    • SY083835
    • AKOS011674533
    • CS-0088535
    • DTXSID30408656
    • MFCD00968468
    • SCHEMBL1107144
    • 53088-69-0
    • A829396
    • AS-59593
    • MDL: MFCD00968468
    • Inchi: 1S/C10H12O2/c1-8-4-3-5-9(6-8)7-10(11)12-2/h3-6H,7H2,1-2H3
    • InChI Key: AWTKFTNNPQGGLX-UHFFFAOYSA-N
    • SMILES: O(C)C(CC1C=CC=C(C)C=1)=O

Computed Properties

  • Exact Mass: 164.08400
  • Monoisotopic Mass: 164.08373
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 3
  • Complexity: 154
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.3
  • Topological Polar Surface Area: 26.3

Experimental Properties

  • Color/Form: Not available
  • Density: 1.035±0.06 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 226.9±9.0 oC (760 Torr),
  • Flash Point: 99.8±17.1 oC,
  • Refractive Index: 1.5045-1.5065
  • Solubility: Slightly soluble (1.3 g/l) (25 o C),
  • PSA: 26.30000
  • LogP: 1.71050
  • Solubility: Not available

Methyl 2-(m-tolyl)acetate Security Information

Methyl 2-(m-tolyl)acetate Customs Data

  • HS CODE:2916399090
  • Customs Data:

    China Customs Code:

    2916399090

    Overview:

    2916399090 Other aromatic monocarboxylic acids. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, Acrylic acid\Acrylates or esters shall be packaged clearly

    Summary:

    2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Methyl 2-(m-tolyl)acetate Production Method

Methyl 2-(m-tolyl)acetate Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:53088-69-0)Methyl 2-(m-tolyl)acetate
Order Number:A829396
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:11
Price ($):191.0

Additional information on Methyl 2-(m-tolyl)acetate

Introduction to Methyl 2-(m-tolyl)acetate (CAS No. 53088-69-0)

Methyl 2-(m-tolyl)acetate, also known by its CAS registry number CAS No. 53088-69-0, is a versatile organic compound with a wide range of applications in various industries. This compound is a methyl ester of 2-(m-tolyl)acetic acid, characterized by its aromatic ring structure and ester functional group. The compound's chemical formula is C11H14O2, and it exists as a colorless liquid with a pleasant fragrance, making it highly suitable for use in perfumery and flavoring agents.

The synthesis of Methyl 2-(m-tolyl)acetate typically involves the esterification reaction between 2-(m-tolyl)acetic acid and methanol in the presence of an acid catalyst such as sulfuric acid or p-toluenesulfonic acid. This reaction is exothermic and can be efficiently carried out under reflux conditions to ensure complete conversion of the reactants into the desired product. The purity of the final product can be confirmed through various analytical techniques, including gas chromatography (GC), high-performance liquid chromatography (HPLC), and nuclear magnetic resonance (NMR) spectroscopy.

One of the most notable applications of Methyl 2-(m-tolyl)acetate is in the fragrance industry, where it is used as a key ingredient in perfumes, colognes, and other personal care products. Its pleasant floral aroma makes it an ideal component for creating complex fragrance blends that appeal to a wide range of consumers. Additionally, this compound is employed in the food industry as a flavoring agent, particularly in the production of beverages, candies, and baked goods, where it imparts a subtle fruity or floral note.

In recent years, there has been growing interest in exploring the potential of Methyl 2-(m-tolyl)acetate in pharmaceutical applications. Researchers have investigated its ability to act as a precursor for the synthesis of bioactive compounds with potential therapeutic properties. For instance, studies have shown that derivatives of this compound exhibit anti-inflammatory and antioxidant activities, suggesting its potential use in drug development.

The environmental impact of Methyl 2-(m-tolyl)acetate has also been a topic of concern among scientists and regulatory bodies. Due to its volatility and biodegradability, this compound is considered to have low persistence in the environment when properly managed. However, measures must still be taken to minimize its release into water bodies and air during industrial processes to prevent any adverse effects on aquatic life or human health.

From a safety standpoint, handling Methyl 2-(m-tolyl)acetate requires adherence to standard laboratory practices and safety protocols. Although it is not classified as a hazardous substance under most regulations, proper ventilation should be ensured when working with large quantities to avoid inhalation exposure. Additionally, skin contact should be minimized by wearing appropriate protective gear such as gloves and lab coats.

In conclusion, Methyl 2-(m-tolyl)acetate (CAS No. 53088-69-0) is a valuable compound with diverse applications across multiple industries. Its unique chemical properties make it an essential ingredient in fragrance and flavor formulations while also presenting opportunities for innovative uses in pharmaceuticals and other advanced materials science applications.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:53088-69-0)Methyl 2-(m-tolyl)acetate
A829396
Purity:99%
Quantity:25g
Price ($):191.0
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