Cas no 53081-25-7 (2,3,4,6-Tetra-O-benzyl-D-galactopyranose)
2,3,4,6-Tetra-O-benzyl-D-galactopyranose Chemical and Physical Properties
Names and Identifiers
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- 2,3,4,6-Tetra-O-benzyl-D-galactose
- 2,3,4,6-Tetra-O-benzyl-D-galactopyranose
- 2,3,4,6-tetrakis-O-(phenylmethyl)-D-Galactose
- 2,3,4,6-Tetra-O-benz
- 2,3,4,6-Tetra-O-benzyl-Dgalactopyranose
- D-Galactose,2,3,4,6-tetrakis-O-(phenylmethyl)-
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- MDL： MFCD00132927
- Inchi： 1S/C34H36O6/c35-21-32(38-23-28-15-7-2-8-16-28)34(40-25-30-19-11-4-12-20-30)33(39-24-29-17-9-3-10-18-29)31(36)26-37-22-27-13-5-1-6-14-27/h1-21,31-34,36H,22-26H2/t31-,32+,33+,34-/m1/s1
- InChI Key： OUHUDRYCYOSXDI-ALMGMPQLSA-N
- SMILES： O(CC1C=CC=CC=1)[C@@H]([C@@H](COCC1C=CC=CC=1)O)[C@@H]([C@H](C=O)OCC1C=CC=CC=1)OCC1C=CC=CC=1
Computed Properties
- Exact Mass: 540.25100
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 40
- Rotatable Bond Count: 17
- Complexity: 649
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 4
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 2
- XLogP3: 4.7
Experimental Properties
- Color/Form: powder
- Density: 1.179±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 60-63 °C
- Boiling Point: 576.06°C (rough estimate)
- Refractive Index: 1.6000 (estimate)
- Solubility: Insuluble (6.5E-4 g/L) (25 oC),
- Water Partition Coefficient: Insoluble in water.
- Stability/Shelf Life: Store in freezer
- PSA: 66.38000
- LogP: 5.67660
- Solubility: Insoluble in water
2,3,4,6-Tetra-O-benzyl-D-galactopyranose Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | L-DY092-50mg |
2,3,4,6-Tetra-O-benzyl-D-galactopyranose |
53081-25-7 | 98% | 50mg |
￥102.0 | 2022-03-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | L-DY092-250mg |
2,3,4,6-Tetra-O-benzyl-D-galactopyranose |
53081-25-7 | 98% | 250mg |
￥192.0 | 2022-03-01 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R000888-1g |
2,3,4,6-Tetra-O-benzyl-D-galactopyranose |
53081-25-7 | 98% | 1g |
￥81 | 2024-05-23 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R000888-5g |
2,3,4,6-Tetra-O-benzyl-D-galactopyranose |
53081-25-7 | 98% | 5g |
￥191 | 2024-05-23 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R000888-250mg |
2,3,4,6-Tetra-O-benzyl-D-galactopyranose |
53081-25-7 | 98% | 250mg |
￥41 | 2024-05-23 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T19890-250mg |
(2R,3S,4S,5R)-2,3,4,6-Tetrakis(benzyloxy)-5-hydroxyhexanal |
53081-25-7 | 95% | 250mg |
￥31.0 | 2023-09-06 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T19890-5g |
(2R,3S,4S,5R)-2,3,4,6-Tetrakis(benzyloxy)-5-hydroxyhexanal |
53081-25-7 | 95% | 5g |
￥178.0 | 2023-09-06 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T19890-1g |
(2R,3S,4S,5R)-2,3,4,6-Tetrakis(benzyloxy)-5-hydroxyhexanal |
53081-25-7 | 95% | 1g |
￥38.0 | 2023-09-06 | |
| Chemenu | CM100376-25g |
D-Galactose,2,3,4,6-tetrakis-O-(phenylmethyl)- |
53081-25-7 | 95+% | 25g |
$*** | 2023-05-30 | |
| Chemenu | CM100376-100g |
D-Galactose,2,3,4,6-tetrakis-O-(phenylmethyl)- |
53081-25-7 | 95+% | 100g |
$*** | 2023-05-30 |
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2,3,4,6-Tetra-O-benzyl-D-galactopyranose Related Literature
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Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
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Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
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Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
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Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
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Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
Additional information on 2,3,4,6-Tetra-O-benzyl-D-galactopyranose
Recent Advances in the Application of 2,3,4,6-Tetra-O-benzyl-D-galactopyranose (CAS: 53081-25-7) in Chemical and Biomedical Research
2,3,4,6-Tetra-O-benzyl-D-galactopyranose (CAS: 53081-25-7) is a key intermediate in carbohydrate chemistry, widely used in the synthesis of complex oligosaccharides, glycoconjugates, and glycodendrimers. Recent studies have highlighted its significance in drug discovery, vaccine development, and targeted drug delivery systems. This research brief provides an overview of the latest advancements and applications of this compound in the chemical and biomedical fields.
One of the most notable recent applications of 2,3,4,6-Tetra-O-benzyl-D-galactopyranose is in the synthesis of glycan-based vaccines. Researchers have utilized this compound to create structurally defined glycans that mimic pathogen-associated molecular patterns (PAMPs), enhancing the immune response. A 2023 study published in the Journal of Medicinal Chemistry demonstrated its efficacy in developing a novel vaccine candidate against Streptococcus pneumoniae, showcasing improved antigenicity and stability.
In the realm of targeted drug delivery, 2,3,4,6-Tetra-O-benzyl-D-galactopyranose has been employed to functionalize nanoparticles for liver-specific delivery. The compound's galactose moiety interacts with asialoglycoprotein receptors (ASGPRs) on hepatocytes, enabling precise targeting. Recent work in Advanced Drug Delivery Reviews (2024) highlighted its role in improving the bioavailability of antiviral drugs, reducing off-target effects, and minimizing systemic toxicity.
Furthermore, advancements in synthetic methodologies have streamlined the production of 2,3,4,6-Tetra-O-benzyl-D-galactopyranose, making it more accessible for large-scale applications. A 2024 study in Organic Letters introduced a novel catalytic approach that reduces the number of synthetic steps while maintaining high yield and purity. This innovation is expected to lower production costs and facilitate broader use in both academic and industrial settings.
In conclusion, 2,3,4,6-Tetra-O-benzyl-D-galactopyranose (CAS: 53081-25-7) continues to be a versatile and valuable tool in chemical and biomedical research. Its applications in vaccine development, targeted drug delivery, and synthetic chemistry underscore its importance in advancing therapeutic strategies. Future research is likely to explore its potential in other areas, such as diagnostics and personalized medicine, further expanding its impact on the field.
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