• 1. An investigation of surface properties, local elastic modulus and interaction with simulated pulmonary surfactant of surface modified inhalable voriconazole dry powders using atomic force microscopy
  Michael Kappl,Paul M. Young,Daniela Traini,Sanyog Jain RSC Adv., 2016,6, 25789-25798
• 2. An analyte-triggered artificial peroxidase system based on dimanganese complex for a versatile enzyme assay?
  Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
• 3. An insight into the hybridization mechanism of hairpin DNA physically immobilized on chemically modified graphenes
  Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
• 4. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?
  Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
• 5. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylhydrazines
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

5-Chloro-2-fluorophenylhydrazine hydrochloride (CAS No. 529512-80-9)

5-Chloro-2-fluorophenylhydrazine hydrochloride is a versatile compound with significant applications in various fields of chemistry and materials science. This compound, identified by the CAS registry number 529512-80-9, has garnered attention due to its unique chemical properties and potential for use in advanced chemical synthesis. Recent studies have highlighted its role in the development of novel materials and its potential as an intermediate in the synthesis of bioactive compounds.

The molecular structure of 5-chloro-2-fluorophenylhydrazine hydrochloride is characterized by a phenyl ring substituted with chlorine and fluorine atoms at the 5 and 2 positions, respectively. This substitution pattern imparts specific electronic and steric properties to the molecule, making it highly reactive under certain conditions. The presence of the hydrazine group further enhances its reactivity, enabling it to participate in a wide range of chemical transformations.

Recent research has focused on the application of 5-chloro-2-fluorophenylhydrazine hydrochloride in the synthesis of heterocyclic compounds, which are of great importance in drug discovery and materials science. For instance, studies have demonstrated its utility in the formation of pyrazoles, imidazoles, and other nitrogen-containing heterocycles through cyclization reactions. These compounds are known for their biological activity and potential applications in pharmaceuticals.

In addition to its role as a synthetic intermediate, 5-chloro-2-fluorophenylhydrazine hydrochloride has been explored for its ability to act as a reducing agent in certain chemical reactions. Its redox properties have been studied extensively, with recent findings suggesting its potential use in green chemistry applications. This compound has also been employed in the synthesis of metal complexes, which are valuable in catalysis and sensing technologies.

The synthesis of 5-chloro-2-fluorophenylhydrazine hydrochloride typically involves multi-step processes that require precise control over reaction conditions. Recent advancements in synthetic methodologies have enabled higher yields and improved purity levels, making this compound more accessible for large-scale applications. Researchers have also investigated alternative routes to synthesize this compound, including microwave-assisted synthesis and continuous flow processes, which offer advantages in terms of reaction time and energy efficiency.

From an environmental perspective, the handling and storage of 5-chloro-2-fluorophenylhydrazine hydrochloride must adhere to standard laboratory safety protocols. Its stability under various conditions has been thoroughly evaluated, ensuring safe usage in both academic and industrial settings. Furthermore, recent studies have examined its biodegradability and environmental impact, providing valuable insights into sustainable practices for its utilization.

In conclusion, 5-chloro-2-fluorophenylhydrazine hydrochloride (CAS No. 529512-80-9) is a valuable compound with diverse applications across multiple disciplines. Its unique chemical properties, coupled with ongoing research into its synthesis and applications, position it as a key player in modern chemical innovation. As new discoveries emerge, this compound is expected to contribute even more significantly to advancements in chemistry and related fields.

• 517920-75-1((3-chloro-2-fluorophenyl)hydrazine hydrochloride)
• 64548-20-5((4-Chloro-2-fluorophenyl)hydrazine)
• 497959-29-2(2-Chloro-4-fluorophenylhydrazine hydrochloride)
• 2106-05-0(5-Chloro-2-fluoroaniline)
• 2924-15-4((2-fluorophenyl)hydrazine hydrochloride)
• 175135-74-7(3-Chloro-4-fluorophenylhydrazine Hydrochloride)
• 84282-78-0(3-Chloro-4-fluorophenylhydrazine)
• 175276-74-1((2-Chloro-6-fluorophenyl)hydrazine)
• 119452-65-2((2-Chloro-4-fluorophenyl)hydrazine)
• 64172-78-7(4-Chloro-2-fluorophenylhydrazine hydrochloride)