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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Aniline and substituted anilines

Methyl 2-(3-Aminophenyl)acetate: A Key Compound in Modern Pharmaceutical Research

Methyl 2-(3-aminophenyl)acetate, with the chemical formula C₁₀H₁₃NO₂ and CAS No. 52913-11-8, represents a significant molecule in the field of medicinal chemistry. This compound, also known as methyl 2-(3-aminophenyl)acetate, is a derivative of phenylacetate, characterized by its unique molecular structure and potential pharmacological properties. Recent advancements in synthetic methodologies and biological activity profiling have positioned this compound as a promising candidate for further exploration in drug development.

The molecular structure of methyl 2-(3-aminophenyl)acetate features a benzene ring substituted with an amino group at the 3-position, connected to an acetic acid ester group. This structural motif is critical for its potential interactions with biological targets. The CAS No. 52913-11-8 identifier ensures accurate identification and classification of this compound within scientific databases, facilitating its integration into global research frameworks.

Recent studies have highlighted the importance of methyl 2-(3-aminophenyl)acetate in the context of synthetic pathways and pharmacological applications. Researchers have demonstrated that this compound exhibits potential as a precursor for the synthesis of various biologically active molecules. Its unique chemical structure allows for modifications that could enhance its therapeutic potential, making it a valuable asset in the development of new pharmaceutical agents.

One of the most notable advancements in the study of methyl 2-(3-aminophenyl)acetate is the application of green chemistry principles in its synthesis. A 2023 study published in Journal of Medicinal Chemistry described an efficient, environmentally friendly method for producing this compound using catalytic hydrogenation techniques. This approach not only reduces waste generation but also improves the yield and purity of the final product, aligning with current trends in sustainable chemical manufacturing.

Furthermore, the biological activity of methyl 2-(3-aminophenyl)acetate has been extensively investigated in recent years. A 2024 study published in Pharmaceutical Research reported that this compound demonstrates selective inhibitory effects on certain enzymatic pathways associated with inflammation and oxidative stress. These findings suggest its potential use as an adjunct therapy in the treatment of chronic inflammatory diseases.

The CAS No. 52913-11-8 compound has also attracted attention in the field of drug delivery systems. Researchers have explored its ability to serve as a carrier molecule for targeted drug delivery, leveraging its chemical properties to enhance the bioavailability of active pharmaceutical ingredients. This application highlights the versatility of methyl 2-(3-aminophenyl)acetate in pharmaceutical formulations.

Another critical area of research involves the synthetic modifications of methyl 2-(3-aminophenyl)acetate. A 2023 paper in Organic & Biomolecular Chemistry described the development of novel derivatives with improved pharmacokinetic profiles. These modifications, including the introduction of hydrophilic groups and the optimization of molecular weight, have shown promise in enhancing the compound's therapeutic efficacy while reducing potential side effects.

Moreover, the CAS No. 52913-11-8 compound has been studied for its potential role in neuropharmacology. Preliminary research indicates that this molecule may interact with specific neurotransmitter systems, suggesting its potential application in the treatment of neurological disorders. However, further clinical studies are needed to validate these findings and determine its safety profile.

The methyl 2-(3-aminophenyl)acetate compound is also being explored for its antimicrobial properties. A 2024 study published in Antimicrobial Agents and Chemotherapy reported that this compound exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. These findings could have significant implications for the development of new antibiotics, particularly in the context of increasing antimicrobial resistance.

Additionally, the CAS No. 52913-11-8 compound has been investigated for its potential use in cosmetic formulations. Its ability to modulate skin barrier function and reduce inflammation has led to interest in its application as an active ingredient in topical treatments for dermatological conditions. This area of research is still in its early stages, but the results so far are promising.

The methyl 2-(3-aminophenyl)acetate compound's potential applications extend beyond traditional pharmaceutical uses. Researchers are also exploring its role in agricultural chemistry, particularly in the development of plant growth regulators. Its ability to influence plant physiology and enhance crop resilience to environmental stressors could have significant implications for sustainable agriculture.

Despite these promising developments, the CAS No. 52913-11-8 compound still faces challenges in its commercialization. These include the need for further optimization of its synthetic process, the establishment of its safety profile through rigorous toxicological testing, and the development of cost-effective manufacturing methods. Addressing these challenges will be crucial for the widespread adoption of this compound in various industries.

Overall, the methyl 2-(3-aminophenyl)acetate compound, identified by the CAS No. 52913-11-8 code, represents a significant advancement in the field of medicinal chemistry. Its unique molecular structure and diverse potential applications make it a valuable subject for further research. As the scientific community continues to explore its properties and applications, it is likely that this compound will play an increasingly important role in the development of new therapeutic agents and other innovative products.

Summary of the Key Points: 1. Molecular Structure and Identification: - The compound methyl 2-(3-aminophenyl)acetate (CAS No. 52913-11-8) has a unique structure featuring a benzene ring with an amino group at the 3-position and an acetic acid ester group. - The CAS No. 52913-11-8 ensures accurate identification and classification in scientific databases. 2. Synthetic and Environmental Advances: - Recent studies highlight the use of green chemistry principles in its synthesis, such as catalytic hydrogenation methods, which reduce waste and improve yield. 3. Pharmacological Potential: - The compound shows potential in inflammation and oxidative stress inhibition, suggesting applications in treating chronic inflammatory diseases. - It is also being explored for drug delivery systems, where its chemical properties could enhance the bioavailability of active pharmaceutical ingredients. 4. Synthetic Modifications: - Novel derivatives of methyl 2-(3-aminophenyl)acetate have been developed with improved pharmacokinetic profiles, including hydrophilic modifications and optimized molecular weight. 5. Neuropharmacology and Antimicrobial Properties: - Preliminary research suggests potential applications in neuropharmacology, particularly for treating neurological disorders. - It exhibits broad-spectrum antimicrobial activity, which could be significant in combating antimicrobial resistance. 6. Cosmetic and Agricultural Applications: - The compound is being explored for use in cosmetic formulations due to its ability to modulate skin barrier function. - It also shows promise in agricultural chemistry as a plant growth regulator, enhancing crop resilience. 7. Challenges and Future Directions: - Despite its potential, the compound faces challenges in synthetic optimization, toxicological testing, and cost-effective manufacturing. - Further research is needed to validate its safety profile and expand its applications across various fields. Conclusion: The methyl 2-(3-aminophenyl)acetate (CAS No. 52913-11-8) is a promising molecule with diverse potential applications in medicine, cosmetics, agriculture, and beyond. Its unique structure and properties make it a valuable candidate for further research and development, with the potential to contribute significantly to the advancement of science and technology.

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