• 1. An integrated microfluidic platform for sensitive and rapid detection of biological toxins?
  Robert J. Meagher,Anson V. Hatch,Ronald F. Renzi,Anup K. Singh Lab Chip, 2008,8, 2046-2053
• 2. An integrated process of CO2 capture and in situ hydrogenation to formate using a tunable ethoxyl-functionalized amidine and Rh/bisphosphine system?
  Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
• 3. An artificial photosynthetic system for photoaccumulation of two electrons on a fused dipyridophenazine (dppz)–pyridoquinolinone ligand?
  Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
• 4. Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes?
  Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
• 5. An artificial photosynthesis system comprising a covalent triazine framework as an electron relay facilitator for photochemical carbon dioxide reduction?
  Siquan Zhang,Shengyao Wang,Liping Guo,Hao Chen,Bien Tan,Shangbin Jin J. Mater. Chem. C, 2020,8, 192-200

Introduction to 4-(methylsulfanyl)-2-propanamidobutanoic Acid (CAS No. 52811-70-8)

4-(methylsulfanyl)-2-propanamidobutanoic acid, identified by its Chemical Abstracts Service (CAS) number 52811-70-8, is a specialized organic compound that has garnered significant attention in the field of pharmaceutical and biochemical research. This compound belongs to the class of sulfonamides and amides, featuring a unique structural framework that lends itself to diverse applications in drug development and biochemical studies.

The molecular structure of 4-(methylsulfanyl)-2-propanamidobutanoic acid consists of a butanoic acid backbone substituted with an amide group at the second carbon and a methylsulfanyl (dimethyl sulfide) moiety at the fourth carbon. This configuration imparts specific chemical properties that make it a valuable intermediate in synthetic chemistry and a potential candidate for therapeutic applications. The presence of both amide and sulfonamide functionalities enhances its reactivity, allowing for further derivatization and functionalization, which is crucial in medicinal chemistry.

In recent years, there has been growing interest in the development of novel compounds with sulfonamide and amide functionalities due to their broad spectrum of biological activities. 4-(methylsulfanyl)-2-propanamidobutanoic acid has been explored in several preclinical studies for its potential role in modulating biological pathways associated with inflammation, pain, and metabolic disorders. Its structural features suggest that it may interact with enzymes and receptors involved in these pathways, making it a promising candidate for further investigation.

One of the most compelling aspects of 4-(methylsulfanyl)-2-propanamidobutanoic acid is its versatility as a building block in drug discovery. Researchers have utilized this compound to synthesize derivatives with enhanced pharmacological properties. For instance, modifications to the amide or sulfonamide groups can alter the compound's solubility, bioavailability, and target specificity. Such flexibility is essential in developing drugs that can effectively reach their intended biological targets while minimizing side effects.

The pharmaceutical industry has been particularly interested in compounds that exhibit anti-inflammatory and analgesic properties. 4-(methylsulfanyl)-2-propanamidobutanoic acid has shown promise in preliminary studies as a precursor for developing new anti-inflammatory agents. Its ability to inhibit key enzymes involved in the inflammatory cascade, such as cyclooxygenase (COX) and lipoxygenase (LOX), makes it a valuable candidate for further exploration. Additionally, its structural similarity to known therapeutic agents suggests that it may have complementary mechanisms of action.

Beyond its pharmaceutical applications, 4-(methylsulfanyl)-2-propanamidobutanoic acid has found utility in biochemical research. Its unique chemical properties make it an excellent tool for studying enzyme kinetics and substrate specificity. By using this compound as a substrate or inhibitor, researchers can gain insights into the mechanisms of various metabolic pathways. This information is crucial for understanding disease processes and developing targeted therapies.

The synthesis of 4-(methylsulfanyl)-2-propanamidobutanoic acid is another area where this compound has made significant contributions. Advanced synthetic methodologies have been employed to produce this compound with high purity and yield, enabling researchers to conduct more sophisticated experiments without compromising on quality. Techniques such as solid-phase synthesis and catalytic asymmetric hydrogenation have been particularly useful in achieving these goals.

In conclusion, 4-(methylsulfanyl)-2-propanamidobutanoic acid (CAS No. 52811-70-8) is a multifaceted compound with diverse applications in pharmaceutical research and biochemical studies. Its unique structural features make it a valuable intermediate for drug development, while its biological activities suggest potential therapeutic benefits. As research continues to uncover new applications for this compound, it is likely to play an increasingly important role in the discovery and development of novel treatments for various diseases.

• 1999-34-4(Glycylmethionine)
• 65-82-7(N-Acetyl-L-methionine)
• 1115-47-5(N-Acetyl-DL-methionine)
• 1509-92-8(N-Acetyl-D-methionine)
• 1999-43-5(DL-Alanyl-DL-methionine)
• 1109-92-8(N-ACETYL-D-METHIONINE)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)