Cas no 527-75-3 (Erythromycin B (~90%))
Erythromycin B (~90%) is a macrolide antibiotic derived from Saccharopolyspora erythraea, structurally similar to Erythromycin A but with distinct pharmacokinetic properties. This compound exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive and some Gram-negative bacteria by inhibiting protein synthesis via binding to the 50S ribosomal subunit. The ~90% purity ensures reliable performance in research and pharmaceutical applications, offering a well-characterized intermediate for derivative synthesis or mechanistic studies. Its stability under controlled conditions and consistent batch-to-batch quality make it suitable for analytical standards or antimicrobial investigations. Erythromycin B is particularly noted for its role in studying structure-activity relationships within the macrolide class.
Erythromycin B (~90%) structure
Product Name:Erythromycin B (~90%)
CAS No:527-75-3
MF:C37H67NO12
MW:717.927393198013
CID:827617
PubChem ID:9918244
Update Time:2025-05-28
Erythromycin B (~90%) Chemical and Physical Properties
Names and Identifiers
-
- Erythromycin B
- 12-Deoxyerythromycin
- (3R,4S,6R,7R,9R,11R,12S,13R,14R)-6-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
- SCHEMBL193989
- Abbott-24091
- ERYTHROMYCIN, 12-DEOXY-
- BERYTHROMYCIN [INN]
- DTXSID501023765
- Berythromycine [INN-French]
- ERB
- BERYTHROMYCIN [WHO-DD]
- Erythromycin B (~90%)
- AN686JJ1YI
- Berythromycinum
- BDBM85998
- Beritromicina
- ERYTHROMYCIN B (150 MG)
- Abbot 24091
- ERYTHROMYCIN B [USP-RS]
- IDRYSCOQVVUBIJ-PPGFLMPOSA-N
- BRN 5206722
- C06653
- Berythromycin (USAN/INN)
- BERYTHROMYCIN [USAN]
- Q27103559
- (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
- CHEBI:28196
- CHEMBL3220708
- D03098
- 527-75-3
- (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
- ERYTHROMYCIN, 12-DEOXY
- UNII-AN686JJ1YI
- Berythromycin [USAN:INN]
- NS00011669
- Berythromycinum [INN-Latin]
- Berythromycin
- Berythromycine
- Erythromycin-B
- LMPK04000012
- (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-4-(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyloxy)-14-ethyl-7,12-dihydroxy-6-[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyloxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
- Beritromicina [INN-Spanish]
- G91247
-
- Inchi： 1S/C37H67NO12/c1-14-26-20(4)29(40)21(5)28(39)18(2)16-36(9,44)33(50-35-30(41)25(38(11)12)15-19(3)46-35)22(6)31(23(7)34(43)48-26)49-27-17-37(10,45-13)32(42)24(8)47-27/h18-27,29-33,35,40-42,44H,14-17H2,1-13H3/t18-,19-,20+,21+,22+,23-,24+,25+,26-,27+,29+,30-,31+,32+,33-,35+,36-,37-/m1/s1
- InChI Key： IDRYSCOQVVUBIJ-PPGFLMPOSA-N
- SMILES： O([C@H]1[C@@H]([C@H](C[C@@H](C)O1)N(C)C)O)[C@H]1[C@@](C)(C[C@@H](C)C([C@H](C)[C@H]([C@@H](C)[C@@H](CC)OC([C@H](C)[C@H]([C@@H]1C)O[C@H]1C[C@](C)([C@H]([C@H](C)O1)O)OC)=O)O)=O)O
Computed Properties
- Exact Mass: 717.46600
- Monoisotopic Mass: 717.466327
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 4
- Hydrogen Bond Acceptor Count: 13
- Heavy Atom Count: 50
- Rotatable Bond Count: 7
- Complexity: 1130
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 9
- Undefined Atom Stereocenter Count : 9
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.9
- Topological Polar Surface Area: 174
Experimental Properties
- Density: 1.2±0.1 g/cm3
- Melting Point: >187oC (dec.)
- Boiling Point: 807.6±65.0 °C at 760 mmHg
- Flash Point: 442.2℃
- Refractive Index: 1.526?
- Solubility: Chloroform (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly, Heated), Met
- PSA: 173.68000
- LogP: 2.67070
- Vapor Pressure: 0.0±6.5 mmHg at 25°C
Erythromycin B (~90%) Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Hazard Category Code： 36
- Safety Instruction： 26
-
Hazardous Material Identification：
- Storage Condition：-20?°C Freezer
Erythromycin B (~90%) Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | E649975-10mg |
Erythromycin B (~90%) |
527-75-3 | 10mg |
$ 148.00 | 2023-09-07 | ||
| TRC | E649975-25mg |
Erythromycin B (~90%) |
527-75-3 | 25mg |
$ 265.00 | 2023-09-07 | ||
| TRC | E649975-50mg |
Erythromycin B (~90%) |
527-75-3 | 50mg |
$481.00 | 2023-05-18 | ||
| TRC | E649975-100mg |
Erythromycin B (~90%) |
527-75-3 | 100mg |
$ 931.00 | 2023-09-07 | ||
| TRC | E649975-250mg |
Erythromycin B (~90%) |
527-75-3 | 250mg |
$2076.00 | 2023-05-18 | ||
| TRC | E649975-500mg |
Erythromycin B (~90%) |
527-75-3 | 500mg |
$2951.00 | 2023-05-18 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-362735-1 mg |
Erythromycin B, |
527-75-3 | 1mg |
￥707.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-362735A-5 mg |
Erythromycin B, |
527-75-3 | 5mg |
￥3,542.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-362735B-20 mg |
Erythromycin B, |
527-75-3 | 20mg |
￥13,538.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-362735C-50 mg |
Erythromycin B, |
527-75-3 | 50mg |
￥20,141.00 | 2023-07-10 |
Erythromycin B (~90%) Related Literature
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
-
Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
-
Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
-
David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
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