Cas no 52574-82-0 (2-bromo-3-methylbutanoyl chloride)
2-Bromo-3-methylbutanoyl chloride is a halogenated acyl chloride derivative with significant utility in organic synthesis. Its reactive carbonyl and bromine substituents make it a versatile intermediate for nucleophilic substitution and acylation reactions, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty compounds. The branched alkyl chain enhances steric influence, allowing selective reactivity in complex molecular frameworks. The compound’s high electrophilicity facilitates efficient coupling with amines, alcohols, and other nucleophiles. Proper handling under anhydrous conditions is essential due to its moisture sensitivity. This reagent is valued for its ability to introduce both bromo and acyl functionalities in a single step, streamlining synthetic routes.
52574-82-0 structure
Product Name:2-bromo-3-methylbutanoyl chloride
CAS No:52574-82-0
MF:C5H8BrClO
MW:199.473420143127
CID:937139
PubChem ID:12486982
Update Time:2025-06-07
2-bromo-3-methylbutanoyl chloride Chemical and Physical Properties
Names and Identifiers
-
- alpha-Bromoisovalerylchloride
- 2-bromo-3-methylbutanoyl chloride
- 52574-82-0
- DB-364746
- AKOS006275730
- 2-Bromo-3-methyl butyryl chloride
- alpha-bromoisovaleryl chloride
- 2-bromo-3-methylbutanoylchloride
- a-Bromoisovaleroyl chloride
- SCHEMBL1605284
- 2-bromo-3-methylbutyryl chloride
- EN300-113888
- 27109-47-3
- Bromisovalerylchlorid
- alpha-bromo-isovaleryl chloride
- G32389
-
- Inchi： 1S/C5H8BrClO/c1-3(2)4(6)5(7)8/h3-4H,1-2H3
- InChI Key： MVYUMPZRKNBHOP-UHFFFAOYSA-N
- SMILES： BrC(C(=O)Cl)C(C)C
Computed Properties
- Exact Mass: 197.94471g/mol
- Monoisotopic Mass: 197.94471g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 8
- Rotatable Bond Count: 2
- Complexity: 92.4
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.9
- Topological Polar Surface Area: 17.1?2
2-bromo-3-methylbutanoyl chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-113888-0.1g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 0.1g |
$62.0 | 2023-10-26 | |
| Enamine | EN300-113888-0.25g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 0.25g |
$88.0 | 2023-10-26 | |
| Enamine | EN300-113888-0.5g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 0.5g |
$164.0 | 2023-10-26 | |
| Enamine | EN300-113888-1.0g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 1g |
$241.0 | 2023-06-09 | |
| Enamine | EN300-113888-2.5g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 2.5g |
$474.0 | 2023-10-26 | |
| Enamine | EN300-113888-5.0g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 5g |
$701.0 | 2023-06-09 | |
| Enamine | EN300-113888-10.0g |
2-bromo-3-methylbutanoyl chloride |
52574-82-0 | 95% | 10g |
$1040.0 | 2023-06-09 | |
| 1PlusChem | 1P00DNAU-1g |
alpha-Bromoisovalerylchloride |
52574-82-0 | 1g |
$131.00 | 2025-02-26 | ||
| 1PlusChem | 1P00DNAU-5g |
alpha-Bromoisovalerylchloride |
52574-82-0 | 5g |
$494.00 | 2025-02-26 | ||
| 1PlusChem | 1P00DNAU-25g |
alpha-Bromoisovalerylchloride |
52574-82-0 | 25g |
$1533.00 | 2025-02-26 |
2-bromo-3-methylbutanoyl chloride Related Literature
-
Xingjie Wu,Linzhu Zhou,Yue Su,Chang-Ming Dong J. Mater. Chem. B, 2016,4, 2142-2152
-
Tanya Ostapenko,Peter J. Collings,Samuel N. Sprunt,J. T. Gleeson Soft Matter, 2013,9, 9487-9498
-
Ying Li,Weirong Yao,Yunfei Xie,Renjun Pei RSC Adv., 2015,5, 98724-98729
-
Richa Sardessai,Shobhana Krishnaswamy,Mysore S. Shashidhar CrystEngComm, 2012,14, 8010-8016
-
Yingbo Li,Nada Mehio,Huizhou Liu,Sheng Dai Green Chem., 2015,17, 2981-2993
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