• 1. Transition metal-catalyzed deoxydehydration: missing pieces of the puzzle
  Friederike C. Jentoft Catal. Sci. Technol. 2022 12 6308
• 2. Probing the mechanism of benzaldehyde reduction to chiral hydrobenzoin on the CNT surface under near-UV light irradiation
  Yunwei Wang,Pengju Ren,Xianmo Gu,Xiaodong Wen,Yingyong Wang,Xiangyun Guo,Eric R. Waclawik,Huaiyong Zhu,Zhanfeng Zheng Green Chem. 2016 18 1482
• 3. Mechanism and optimisation of the homoboroproline bifunctional catalytic asymmetric aldol reaction: Lewis acid tuning through in situ esterification
  Irene Georgiou,Andrew Whiting Org. Biomol. Chem. 2012 10 2422
• 4. A general approach using spiroborate reversible cross-linked Au nanoparticles for visual high-throughput screening of chiral vicinal diols
  Weili Wei,Li Wu,Can Xu,Jinsong Ren,Xiaogang Qu Chem. Sci. 2013 4 1156
• 5. Preparation of chiral 3-oxocycloalkanecarbonitrile and its derivatives by crystallization-induced diastereomer transformation of ketals with chiral 1,2-diphenylethane-1,2-diol
  Yohei Yamashita,Daisuke Maki,Shiho Sakurai,Takumi Fuse,Shoji Matsumoto,Motohiro Akazome RSC Adv. 2018 8 32601

• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

(1R,2R)-1,2-Diphenylethane-1,2-Diol: A Comprehensive Overview

(1R,2R)-1,2-Diphenylethane-1,2-diol, also known by its CAS number 52340-78-0, is a compound of significant interest in both academic and industrial research. This compound is a diol derivative with a unique structure that combines two phenyl groups attached to a central ethane backbone, each bearing a hydroxyl group. The stereochemistry of the molecule is defined by its (1R,2R) configuration, which plays a crucial role in its chemical reactivity and biological activity.

The synthesis of (1R,2R)-1,2-Diphenylethane-1,2-diol has been extensively studied, with researchers exploring various methodologies to achieve high enantiomeric excess and optimal yields. Recent advancements in asymmetric catalysis have enabled the development of more efficient routes for its preparation. For instance, the use of chiral catalysts such as palladium complexes has been reported to facilitate the enantioselective formation of this compound from its corresponding dihalide precursors.

One of the most intriguing aspects of (1R,2R)-1,2-Diphenylethane-1,2-diol is its versatile reactivity. The compound serves as an excellent substrate for various organic transformations due to the electronic and steric properties of its phenyl groups and hydroxyl functionalities. Recent studies have highlighted its potential as a building block in the construction of complex molecular architectures. For example, researchers have utilized this compound in the synthesis of bioactive molecules with applications in drug discovery.

The physical and chemical properties of (1R,2R)-1,2-Diphenylethane-1,2-diol have been thoroughly characterized using modern analytical techniques. Its melting point and solubility data are well-documented in recent literature, providing valuable insights into its behavior under different conditions. Additionally, spectroscopic studies have revealed detailed information about its molecular structure and intermolecular interactions.

In terms of applications, (1R,2R)-1,2-Diphenylethane-1,2-diol has found utility in diverse fields such as materials science and pharmaceuticals. Its ability to form stable complexes with metal ions has made it a valuable ligand in coordination chemistry studies. Furthermore, recent research has explored its role as an intermediate in the synthesis of advanced materials with tailored properties.

The biological activity of (1R,2R)-1,2-Diphenylethane-1,2-diol has also been a focal point of recent investigations. Studies have demonstrated that this compound exhibits potential anti-inflammatory and antioxidant properties under specific experimental conditions. These findings underscore its potential as a lead compound for further drug development efforts.

In conclusion, (1R,2R)-Diphenylethane- diol continues to be an area of active research due to its unique structure and promising applications across multiple disciplines. As new methodologies and insights emerge from ongoing studies,
this compound is likely to play an increasingly important role in both academic research and industrial applications.

• 579-43-1((R,S)-Dihydrobenzoin)
• 27134-24-3([1,1'-Biphenyl]-ar,ar'-diol,ar,ar'-dimethyl-)
• 655-48-1((+/-)-Hydrobenzoin)
• 1855-09-0(1-Phenyl-1,2-propanediol (Mixture of Diastereomers))
• 492-70-6(HYDROBENZOIN)
• 63180-94-9(EINECS 210-374-9)
• 15242-78-1( )
• 56165-22-1((R,R)-(+)-HYDROBENZOIN 99+%)
• 2325-10-2((S,S)-(-)-Hydrobenzoin)
• 40421-52-1(erythro-1-Phenylpropane-1,2-diol)