• 1. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 2. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 3. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 5. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboximidic acids and derivatives Imidoesters

Comprehensive Overview of Ethyl 2-Methylpropanecarboximidate Hydrochloride (CAS No. 52070-18-5)

Ethyl 2-methylpropanecarboximidate hydrochloride (CAS No. 52070-18-5) is a specialized organic compound widely utilized in pharmaceutical synthesis, agrochemical research, and fine chemical production. This compound, often referred to as a carboximidate derivative, plays a pivotal role in the formation of heterocyclic structures and serves as a key intermediate in the synthesis of bioactive molecules. Its molecular formula, C₆H₁₄ClNO, highlights its unique chemical properties, including reactivity as an imidate ester and stability in hydrochloride salt form.

In recent years, the demand for ethyl 2-methylpropanecarboximidate HCl has surged due to its applications in peptide coupling and prodrug design, aligning with the growing interest in targeted drug delivery systems. Researchers frequently search for "CAS 52070-18-5 solubility" or "ethyl 2-methylpropanecarboximidate hydrochloride synthesis," reflecting its technical relevance. The compound’s compatibility with Green Chemistry principles also makes it a subject of interest, as industries seek sustainable alternatives to traditional reagents.

The compound’s nomenclature includes several long-tail keywords such as "ethyl isobutyrimidate hydrochloride" (a common synonym) and "2-methylpropanecarboximidate derivatives," which are critical for academic literature searches. Analytical techniques like HPLC and NMR spectroscopy are typically employed to verify its purity, a topic frequently queried in scientific forums. Notably, its stability under anhydrous conditions and reactivity with nucleophiles are key discussion points in synthetic chemistry circles.

From an industrial perspective, 52070-18-5 is often explored for scalability in batch processing, with patents highlighting its use in chiral auxiliary preparation. Environmental considerations, such as "biodegradability of imidate salts," are emerging as hot topics, linking this compound to broader discussions on eco-friendly chemical manufacturing. Regulatory compliance, particularly regarding REACH and GMP standards, further underscores its safe handling protocols.

Innovative applications of ethyl 2-methylpropanecarboximidate hydrochloride extend to material science, where it aids in polymer modification. Its role in cross-coupling reactions (e.g., with boronic acids) has been cited in recent publications, addressing the demand for "C–N bond formation strategies." As synthetic methodologies evolve, this compound remains a versatile tool for high-yield transformations, cementing its status in modern organic chemistry.

• 20914-92-5(Ethyl 3-ethoxypropanimidate;hydrochloride)
• 63190-44-3(Ethyl cyclopropanecarboximidoate hydrochloride)
• 58910-26-2(ethyl 2,2-dimethylpropanimidate hydrochloride)
• 66381-67-7(Butyl cyclopropanecarboximidate;hydrochloride)
• 39739-60-1(methyl 2-methylpropanimidoate hydrochloride)
• 52186-79-5(ethyl 2,2-dimethylpropanecarboximidate)
• 52186-76-2(ethyl cyclopropanecarboximidoate)
• 40546-35-8(ethyl propanecarboximidate hydrochloride)
• 1070-17-3(Ethyl propionimidate)
• 1069-52-9(Ethyl 2-methylpropanimidoate)