Cas no 51857-17-1 (NH2-C6-NH-Boc)
NH2-C6-NH-Boc Chemical and Physical Properties
Names and Identifiers
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- N-Boc-1,6-Diaminohexane
- N-(tert-Butoxycarbonyl)-1,6-diaminohexane
- N-Boc-1,6-hexanediamine
- N-BOC-1,6-HEXANEDIAMINE HYDROCHLORIDE
- N-tert-Butoxycarbonyl-1,6-hexanediamine
- tert-Butyl (6-aminohexyl)carbamate
- tert-butyl N-(6-aminohexyl)carbamate
- N-(6-Aminohexyl)carbamic Acid tert-Butyl Ester
- N-(tert-Butoxycarbonyl)-1,6-hexanediamine
- NH2-C6-NH-Boc
- tert-butyl 6-aminohexylcarbamate
- SY030887
- doi:10.14272/RVZPDKXEHIRFPM-UHFFFAOYSA-N
- tert-Butyl-N-(6-aminohexyl)carbamate
- N-tert-butyloxycarbonyl-1,6-diaminohexane
- DTXSID70369777
- RVZPDKXEHIRFPM-UHFFFAOYSA-N
- 2-METHYL-2-PROPANYL (6-AMINOHEXYL)CARBAMATE
- HY-W008296
- 51857-17-1
- Carbamic acid, (6-aminohexyl)-, 1,1-dimethylethyl ester
- FT-0640032
- N-Boc-1,6-diaminohexane;tert-Butyl (6-aminohexyl)carbamate
- SCHEMBL146037
- 6-(Boc-amino)hexylamine
- BP-24324
- Boc hexamethylene diamine
- 10.14272/RVZPDKXEHIRFPM-UHFFFAOYSA-N
- A7634
- N-1-Boc-1,6-diaminohexane HCl
- MFCD00671489
- AKOS015841498
- EN300-204077
- GS-4220
- J-523489
- 6-(t-butoxycarbonylamino)hexylamine
- (6-Amino-hexyl)-carbamic acid tert-butyl ester
- AM20100271
- PHOSPHORICACID2-DIMETHYLAMINO-ETHYLESTER2,2-DIMETHYL-[1,3]DIOXOLAN-4-YLMETHYLESTERMETHYLESTER
- tert-butyl-6-aminohexylcarbamate
- N-mono-tert.butyloxycarbonylhexamethylenediamine
- N-Boc-1,6-hexanediamine, >=98.0% (NT)
- 6-(tert-butoxycarbonylamino)hexylamine
- N-t-Butyloxycarbonyl-1,6-hexamethylenediamine hydrochloride
- t-Boc-N-amido-C6-amine
- N-Boc-1,6-damnohexane
- BCP31219
- N-(t-butoxycarbonyl)-1,6-diaminohexane
- N-(t-butyoxycarbonyl)hexamethylenediamine
- A1375
- CS-W008296
- DB-030129
- BBL102839
- DB-052037
- STL556647
- ALBB-033377
-
- MDL： MFCD00671489
- Inchi： 1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)
- InChI Key： RVZPDKXEHIRFPM-UHFFFAOYSA-N
- SMILES： O(C(NCCCCCCN)=O)C(C)(C)C
- BRN： 2089264
Computed Properties
- Exact Mass: 216.18400
- Monoisotopic Mass: 216.184
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 9
- Complexity: 176
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 2
- XLogP3: 1.4
- Topological Polar Surface Area: 64.4A^2
Experimental Properties
- Color/Form: liquid
- Density: 0.965?g/mL?at 20?°C(lit.)
- Boiling Point: 106-110 oC (0.3 mmHg)
- Flash Point: Fahrenheit: 257 ° f
Celsius: 125 ° c - Refractive Index: n20/D 1.462
- Solubility: Soluble in dichloromethane and ethyl acetate.
- PSA: 64.35000
- LogP: 3.12140
- Solubility: Soluble in water
- Sensitiveness: Air Sensitive
NH2-C6-NH-Boc Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Danger
- Hazard Statement： H314
- Warning Statement： P280,P305+P351+P338,P310
- Hazardous Material transportation number：UN 2735 8/PG 2
- WGK Germany：3
- Hazard Category Code： 34
- Safety Instruction： S26-S36/37/39-S45
- FLUKA BRAND F CODES：10-34
-
Hazardous Material Identification：
- Packing Group：III
- Hazard Level：8
- Safety Term：8
- Packing Group：III
- Risk Phrases：R34
- HazardClass：8
- PackingGroup：II
- Storage Condition：0-10°C
NH2-C6-NH-Boc Customs Data
- HS CODE：2924199090
- Customs Data：
China Customs Code:
2924199090Overview:
2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
NH2-C6-NH-Boc Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 79229-1G |
NH2-C6-NH-Boc |
51857-17-1 | 1g |
￥370.49 | 2023-11-21 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 79229-5G |
NH2-C6-NH-Boc |
51857-17-1 | 5g |
￥1298.03 | 2023-11-21 | ||
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | ARK-09360-100g |
N-TERT-BUTOXYCARBONYL-1,6-HEXANEDIAMINE |
51857-17-1 | 95% | 100g |
$480 | 2023-09-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-BY994-200mg |
NH2-C6-NH-Boc |
51857-17-1 | 97% | 200mg |
￥60.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-BY994-1g |
NH2-C6-NH-Boc |
51857-17-1 | 97% | 1g |
￥104.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-BY994-5g |
NH2-C6-NH-Boc |
51857-17-1 | 97% | 5g |
￥307.0 | 2022-05-30 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | A1375-25G |
N-(tert-Butoxycarbonyl)-1,6-diaminohexane |
51857-17-1 | >98.0%(T) | 25g |
￥790.00 | 2024-04-16 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R014674-1g |
NH2-C6-NH-Boc |
51857-17-1 | 97% | 1g |
￥44 | 2023-06-14 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R014674-5g |
NH2-C6-NH-Boc |
51857-17-1 | 97% | 5g |
￥143 | 2023-06-14 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | N30950-1g |
NH2-C6-NH-Boc |
51857-17-1 | 97% | 1g |
￥38.0 | 2022-04-27 |
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NH2-C6-NH-Boc Related Literature
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Aaron R. Funk,Efram Goldberg,Eddie L. Chang,Scott A. Trammell,D. Andrew Knight Dalton Trans. 2013 42 15617
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Ning Che,Saina Yang,Hongliang Kang,Ruigang Liu,Zhuang Li,Zhijing Liu,Pingping Li,Xiaozhong Qu,Yong Huang Polym. Chem. 2014 5 7109
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Filippo Ronzani,Emmanuel Arzoumanian,Sylvie Blanc,Patrice Bordat,Thierry Pigot,Cyril Cugnet,Esther Oliveros,Mohamed Sarakha,Claire Richard,Sylvie Lacombe Phys. Chem. Chem. Phys. 2013 15 17219
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Mohammad Othman,Didier Desma?le,Patrick Couvreur,Luce Vander Elst,Sophie Laurent,Robert N. Muller,Claudie Bourgaux,Estelle Morvan,Thierry Pouget,Sinda Lepêtre-Mouelhi,Philippe Durand,Ruxandra Gref Org. Biomol. Chem. 2011 9 4367
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Dawanna S. White,Daniel Mongeluzi,Alyson M. Curry,Dickson Donu,Yana Cen RSC Adv. 2022 12 2219
Additional information on NH2-C6-NH-Boc
Comprehensive Overview of NH2-C6-NH-Boc (CAS No. 51857-17-1): Properties, Applications, and Industry Insights
NH2-C6-NH-Boc, with the CAS number 51857-17-1, is a specialized Boc-protected amine derivative widely utilized in organic synthesis, pharmaceutical intermediates, and peptide chemistry. This compound features a hexylamine backbone (C6) linked to a tert-butoxycarbonyl (Boc) protecting group, making it a versatile building block for researchers and industrial applications. Its molecular structure (C11H23NO2) ensures stability under mild conditions while enabling selective deprotection for further functionalization.
In recent years, the demand for NH2-C6-NH-Boc has surged due to its role in peptide drug development, a hotspot in biopharmaceutical research. With the rise of GLP-1 analogs and anticancer peptides, this compound serves as a critical intermediate for N-terminal modification and side-chain protection. Its compatibility with solid-phase peptide synthesis (SPPS) aligns with the industry's shift toward automated, high-yield production methods.
From a synthetic chemistry perspective, 51857-17-1 offers advantages such as high purity (>98%) and low racemization risk, addressing common challenges in chiral molecule synthesis. Researchers frequently search for "Boc-amine solubility" or "NH2-C6-NH-Boc coupling protocols," reflecting its technical relevance. The compound’s solubility in DCM, DMF, and THF further enhances its utility in cross-coupling reactions.
Environmental and regulatory trends also impact its use. As green chemistry gains traction, NH2-C6-NH-Boc is evaluated for biodegradable solvent compatibility and waste reduction in large-scale processes. Analytical techniques like HPLC and LC-MS are commonly employed to monitor its stability, a topic frequently queried in scientific forums.
In summary, CAS 51857-17-1 remains indispensable for drug discovery and material science. Its balance of reactivity and protection-group versatility positions it as a staple in modern laboratories. Future applications may expand into nanotechnology and bioconjugation, driven by ongoing innovations in targeted therapy.
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