Cas no 518057-67-5 (2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride)
2,5-Bis(trifluoromethyl)phenylhydrazine Hydrochloride is a specialized hydrazine derivative used primarily as a key intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds and pharmaceuticals. The presence of two trifluoromethyl groups enhances its electron-withdrawing properties, making it valuable in reactions requiring controlled nucleophilic substitution or cyclization. Its hydrochloride form improves stability and solubility in polar solvents, facilitating handling and storage. This compound is particularly useful in medicinal chemistry for the development of bioactive molecules due to its ability to introduce fluorinated aromatic motifs, which can enhance metabolic stability and binding affinity. High purity and consistent performance make it a reliable choice for research and industrial applications.
518057-67-5 structure
Product Name:2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride
CAS No:518057-67-5
MF:C8H7ClF6N2
MW:280.598001718521
CID:935886
PubChem ID:44717515
Update Time:2025-11-02
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- (2,5-Bis(trifluoromethyl)phenyl)hydrazine hydrochloride
- (2,5-bis(trifluoromethyl)phenyl)hydrazine
- 2,5-bis(trifluoromethyl)-phenyhydrazine(HCl)
- 2,5-BIS(TRIFLUOROMETHYL)PHENYLHYDRAZINE HYDROCHLORIDE
- [2,5-Bis(trifluoromethyl)phenyl]hydrazine monohydrochloride
- 1-(2,5-bis(trifluoroMethyl)phenyl)hydrazine hydrochloride
- Hydrazine,[2,5-bis(trifluoroMethyl)phenyl]-,hydrochloride
- Hydrazine,[2,5-bis(trifluoroMethyl)phenyl]-,hydrochloride (1:1)
- [2,5-bis(trifluoromethyl)phenyl]hydrazine hydrochloride
- DB-328372
- BLAAPLQHIQDNFB-UHFFFAOYSA-N
- 1-(2,5-bis(trifluoromethyl)phenyl)hydrazine HCl
- [2,5-bis-(Trifluoromethyl)phenyl]hydrazine hydrochloride
- MFCD03788549
- 518057-67-5
- [2,5-bis(trifluoromethyl)phenyl]hydrazine;hydrochloride
- SCHEMBL20984701
- 2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride
-
- Inchi： 1S/C8H6F6N2.ClH/c9-7(10,11)4-1-2-5(8(12,13)14)6(3-4)16-15;/h1-3,16H,15H2;1H
- InChI Key： BLAAPLQHIQDNFB-UHFFFAOYSA-N
- SMILES： Cl.FC(C1C=CC(C(F)(F)F)=CC=1NN)(F)F
Computed Properties
- Exact Mass: 280.02000
- Monoisotopic Mass: 280.0201949g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 8
- Heavy Atom Count: 17
- Rotatable Bond Count: 1
- Complexity: 236
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 38?2
Experimental Properties
- PSA: 38.05000
- LogP: 4.58510
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride Customs Data
- HS CODE：2928000090
- Customs Data：
China Customs Code:
2928000090Overview:
2928000090 Other hydrazine(Hydrazine)And chlorhexidine(hydroxylamine)Organic derivatives of.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | T901708-10mg |
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride |
518057-67-5 | 10mg |
$ 50.00 | 2022-06-02 | ||
| TRC | T901708-50mg |
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride |
518057-67-5 | 50mg |
$ 135.00 | 2022-06-02 | ||
| TRC | T901708-100mg |
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride |
518057-67-5 | 100mg |
$ 210.00 | 2022-06-02 |
2,5-Bis(trifluoromethyl)-phenyhydrazine Hydrochloride Related Literature
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Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
-
Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267
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